Sanfilippo syndrome type B (mucopolysaccharidosis III B) is a rare autosomal recessive disease caused by deficiency of alpha-N-acetylglucosaminidase, one of the enzymes required for the lysosomal degradation of heparan sulfate. The gene for this enzyme, NAGLU, recently was isolated, and several mutations were characterized. We have identified, in amplified exons from nine fibroblast cell lines der

This study tests whether the rise of free trade agreements (FTAs) in East Asia since 2000 has been an attempt to manage the growing complexity of trade both between members of that region and each other, as well as between them and the rest of the world. The study uses a measure of dependency based on GDP, as well as a measure of intraindustry trade as indicators. Descriptive statistics showed tha

Det teoretiska ramverket för studie var GLOBE-studien, Hofstedes fyra dimensioner och Sveningssons och Alvessons förhållningssätt till ledarskap. Syftet var att undersöka den personliga upplevelsen hos Svenska ledare. Fokus var på hur kulturella faktorer påverkade ledarskapet när ledarna arbetade med ett utländskt team. Sex svenska ledare som hade arbetat med utländska team i USA, Indien, TysklandThe theoretical framework of the present study was the GLOBE study, Hofstede’s four dimensions and Sveningsson’s and Alvesson’s approach to leadership. The purpose was to examine the personal experience of Swedish leaders. The focus was on the influence of cultural factors on the leadership when the leaders worked with a foreign team. Six Swedish leaders who had been working with foreign teams in

Primary purpose of this thesis is to contribute to the currently rather limited academic literature on Asian expatriates in Turkey since this group has recently been growing in number and is expected to grow in the future. The research aims to see commonalities and derive generalizable inferences on advantages and problems of Asian expatriates in Istanbul. 23 semi-structured and mostly personal in

A game theoretical analysis of international policy is of great interest from an economist’s point of view and game theory has widely been used when analysing international trade, tariffs etc. In this thesis I will use “Cheap-Talk games” to analyse if threats from the U.S. targeting North Korea are having any impact. Cheap talk games are an application of the perfect Bayesian equilibrium of “dynam

During the Edo Period of Japanese history, many loanwords entered the Japanese language through communication with the Dutch. Now, 164 years after the last significant linguistic exchange took place between the Dutch and the Japanese, it is interesting to see what lexical influence still exists in contemporary modern Japanese and which loanwords have fallen out of use. Therefore, the aim of this b

This study aims to broaden the remits of the relatively scant hitherto literature focused on the impact of the changes in macroeconomic indicators on automotive stock returns. Since a considerable fraction of previous empirical research covered multiple industries, historical results may not be directly transferable for the purposes of the analysis of the automotive industry. This article posits t

This thesis unpacks the similarities and dissimilarities between Connecting Europe and Asia – Building blocks for an EU Strategy from 2018 and the Global Gateway from 2021, two Joint Communications from the European Commission and the EEAS on connectivity. The comparison shows that the Global Gateway has followed up on the suggestions for change or creation from the 2018 strategy. It shows that th

This article discusses the role of language skills, mainly with regard to foreign languages, in historical research. Three principal functions of language as a historical method are identified: 1) language skills as a tool for acquiring knowledge of the international state-of-the-art; 2) language skills as a tool for communicating research; and 3) language skills as a tool for interpreting histori

This paper selected two cities in Zhejiang Province, Wenzhou and Yiwu to take a look at the relations between the local government and their private sector since the adoption of the reform and opening policy in the late 1970s, from the angle of the functional transition of the local government's contribution to the development of the private sector. The purpose of this paper was to, through th

Multiple tipping points in the Earth system could be triggered when global warming exceeds specific thresholds. However, the degree of their impact on the East Asian hydroclimate remains uncertain due to the lack of quantitative rainfall records. Here we present an ensemble reconstruction of East Asian summer monsoon (EASM) rainfall since the Last Glacial Maximum (LGM) using nine statistical and m

A successful vaccination program depends on secure vaccine storage as well as safe and effective vaccine delivery. An Internet of Things (IoT) based vaccine distribution and monitoring model, which is used to transport and monitor vaccines to locations where they will be properly kept for eventual use, is developed and tested. Coronavirus (COVID-19) was first identified in December 2019 in Wuhan c

Many species of insects undertake long-range, seasonally reversed migrations, displaying sophisticated orientation behaviors to optimize their migratory trajectories. However, when invasive insects arrive in new biogeographical regions, it is unclear if migrants retain (or how quickly they regain) ancestral migratory traits, such as seasonally preferred flight headings. Here we present behavioral