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File-sharing has become synonym with the “digital economy” where large music conglomerates as well as certain artist voice strong concern over the impact on their bottom line. This research analyzes the music industry, which has been heavily impacted by a major technological shift i.e. the invention, and rollout, of the Internet. We look to the technological shift that has enabled the downloading
This article is a report of the fourth meeting of the Harmonising Outcome Measures for Eczema (HOME) initiative held in Malmö, Sweden on 23–24 April 2015 (HOME IV). The aim of the meeting was to achieve consensus over the preferred outcome instruments for measuring patient-reported symptoms and quality of life for the HOME core outcome set for atopic eczema (AE). Following presentations, which inc
Whole-tree harvesting, i.e. harvesting of stems, branches and tops, has become increasingly common during recent decades due to the increased demand for renewable energy. Whole-tree harvesting leads to an increase in base cation losses from the ecosystem, which can counteract recovery from acidification. An increase in weathering rates due to higher temperatures is sometimes suggested as a process
The X-ray structure of the superantigen staphylococcal enterotoxin H (SEH) has been determined at 1.69 Å resolution. In this paper we present two structures of zinc-free SEH (apoSEH) and one zinc-loaded form of SEH (ZnSEH). SEH exhibits the conventional superantigen (SAg) fold with two characteristic domains. In ZnSEH one zinc ion per SEH molecule is bound to the C-terminal β-sheet in the region i
All three critical points of the evolutionary explanation proposed by Maestripieri et al. may not withstand close scrutiny. Instead, there should be an alternative explanation that has nothing to do with genetic continuity, but stresses the rewarding property of attractiveness that results mainly from sociocultural value assignment and sexual experience pursuit.
We propose a model to consider data dependencies and assess spatial and temporal variability in land use specific floral coverage across landscapes. Data dependence arising from repeated measurements across the flowering season is taken into account using hierarchical Archimedean copulas, where the correlation is assumed to be stronger within seasonal periods than between periods. For each seasona
Our goal was to test a cascade model to identify developmental pathways, or chains of risk, from neighborhood deprivation in childhood to alcohol use disorder (AUD) in young adulthood. Using Swedish general population data, we examined whether exposure to neighborhood deprivation during early and middle childhood was associated with indicators of social functioning in adolescence and emerging adul
Eddy covariance (EC) measurements are often used to validate net ecosystem productivity (NEP) estimated from satellite remote sensing data and biogeochemical models. However, EC measurements represent an integrated flux over their footprint area, which usually differs from respective model grids or remote sensing pixels. Quantifying the uncertainties of scale mismatch associated with gridded flux
Objective: The aim of this investigation was to study differences between male and female patients with stage T1 urinary bladder cancer (UBC) regarding intravesical instillation therapy, second resection and survival. Materials and methods: This study included all patients with non-metastatic primary T1 UBC reported to the Swedish National Register of Urinary Bladder Cancer (SNRUBC) from 1997 to 2
On-line hyphenation of extraction with chromatography has been explored in several different types of combinations. However, monitoring the complete process of a dynamic, continuous-flow extraction is not possible with any hyphenated system reported so far. The current work demonstrates that this challenging task can be effectively fulfilled by using a parallel sampling interface, which mimics the
Repeated administration of monoclonal antibodies (mAb) directed against the CD4 lymphocyte receptor may induce specific, long-lasting unresponsiveness to fully MHC-mismatched cardiac allografts in rats without additional immunosuppression. We assessed the effect of a single dose of murine anti-rat depleting anti-CD4 mAb (OX-38) on allograft survival in high- and low-responder rat strain combinatio
Aims and objectives: To present parents’ lived experience of having a preterm infant cared for at the neonatal unit until discharge from hospital-based neonatal home care (HNHC). Background: Becoming a parent to a preterm infant has been reported as an experience that may influence the parent's lifeworld also after discharge. Interventions have been implemented at the NICUs, for example introducti
Many birds species connected to the agricultural landscape have for several decades fared poorly in Sweden, as well as in Europe as a whole. This is reflected in the decline of the Farmland Bird Index, an official EU indicator for farmland birds specifically, and biodiversity in general. The Swedish Board of Agriculture invited us to propose measures that will improve the conditions for farmland b
Objective. To investigate baseline levels of 12 serum biomarkers that constitute a multibiomarker disease activity test, as predictors of response to methotrexate (MTX) in patients with early rheumatoid arthritis (eRA). Methods. In 298 patients from the Swedish Pharmacotherapy (SWEFOT) clinical trial, baseline serum levels of 12 proteins were analyzed for association with disease activity based on
