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We propose a dynamical model depicting nitrogen (N2) fixation (diazotrophy) in a unicellular cyanobacterium, Crocosphaera watsonii, grown under light limitation and obligate diazotrophy. In this model, intracellular carbon and nitrogen are both divided into a structual pool and a storage pool. An internal pool that explicitly describes the nitrogenase enzyme is also added. The model is successfull
BACKGROUND: It is unclear how diabetes and metformin use is associated with survival of esophageal cancer.METHODS: This population-based cohort study included new cases of esophageal cancer reported in Sweden from 2006 to 2018 with follow-up through 2019. Diabetes status and metformin use were analyzed in relation to all-cause and disease-specific mortality using multivariable Cox regression. The
In recent years, it has been shown that deep eutectic solvents (DES) and similar mixtures solvate and allow for self-assembly of surfactants, serving as potential “green” alternatives as solvents for, for example, templating nanomaterials or drug delivery applications. Which surfactants are soluble and how they self-assemble depends strongly on the mixture components and their molar ratio. He
The frequency modulation transfer property of a backward-wave optical parametric oscillator (BWOPO) is investigated in the context of near-IR pulse compression. The maximum transferrable bandwidth from the pump to the forward wave in a BWOPO is determined by the group dispersion mismatch. In comparison, the third-order phase introduced in a single-grating compressor setup is more detrimental to ac
We report pulse energy scaling enabled by the use of Laguerre-Gaussian single-vortex (LG0,l) beams for spectral broadening in a sub-40 cm long Herriott-type bulk multi-pass cell. Beams with orders l=1−3 are generated by a spatial light modulator, which facilitates rapid and precise reconfiguration of the experimental conditions. 180 fs pulses with 610 uJ pulse energy are post-compressed to 44 fs u
Background and Goal of StudyWe aimed to develop, implement and evaluate a mobile system using off-the-shelf components, torecord and review simulations and debriefings in four separate rooms during standardized simulation courses at multiple centres in Sweden. Ourrequirements were: high quality sound and video; easy to install, use and demount; suitable for transport by courier; no requirement to
Our research aims to develop an intelligent control system for optimizing the operation of lighting systems for a jogging track in the countryside by using adaptive control methods, and optimization of built-in lighting control. Through this, lighting systems will be optimized, energy consumption will be minimized and the lighting system will be adapted to be able to handle a larger amount of loca
The Swedish Research Council is a Swedish government agency and one of the major research financiers in Sweden. As such, its operations are governed by legislation and governmental instructions and policies, which prohibit discrimination and include equal treatment. Consequently, the Swedish Research Council has for a large number of years been working actively against gender bias in their reviews
This study explores the characteristics of individuals affiliated with violent extremist milieus in Sweden, focusing on far-right, far-left, and Islamic extremist milieus. Firstly, by using a compilation of law enforcement and other Swedish population registers, we describe these milieus along a range of demographic, socioeconomic, criminal, mental health, and familial indicators. We then compare
Background & aims: Colorectal cancer (CRC), particularly rectal cancer, often requires neoadjuvant radiotherapy (RT) as part of its treatment plan. Although effective, RT can cause significant gastrointestinal side effects. Because the onset of RT-induced tissue injury can be anticipated, there is an opportunity to apply preventive measures before the damage occurs. This study aimed to assess
Purpose: To compare the performance of targeted temperature management (TTM) at 33 °C using intravascular (IC) vs. surface-cooling (SFC) devices after out-of-hospital cardiac arrest (OHCA). Methods: A post hoc analysis including OHCA patients randomized to hypothermia in the TTM2-trial (NCT02908308) comparing hypothermia with normothermia. The main outcome was cooling performance, defined as the p
High-risk neuroblastomas exhibit a high degree of intratumoral heterogeneity. Single-cell RNA sequencing has greatly improved our understanding of these tumors, but the method lacks cellular tissue context and spatial information about local signaling dynamics. To address this, we profiled untreated and chemotherapy-treated high-risk neuroblastomas from archived, formalin-fixed, paraffin-embedded
This article presents an innovative participatory approach to the ethical aspects of conducting body mapping research. Drawing from experiences from an earlier project with digital sex workers, we examine how body mapping, when integrated with what we term “embodied oscillative ethics,” creates opportunities for meaningful collaboration and knowledge co-creation while addressing complex ethical ch
Electric scooters (e-scooters) have emerged as a fundamental component of urban micro-mobility, particularly in European cities during the Covid-19 pandemic. This study employs the Full Consistency Method (FUCOM) and Kendall rank correlation method to assess the preferences and priorities of university students in Catania, Italy, regarding e-scooter adoption. By analyzing influencing factors, this
This study examines the production of morphosyntax in Swedish-speaking children diagnosed with Developmental Language Disorder (DLD). Data from a Sentence Repetition Task was used to investigate if there is an implicational order according to Processability Theory (PT) in grammatical structures produced by school-age children with DLD. PT is a cognitive theory of language development that assumes
Despite efforts to integrate BIM and BEM, challenges persist, including incomplete data, errors, and the need for manual corrections, all hindering the implementation of sustainable building designs. Professionals in the Swedish architecture, engineering, and construction (AEC) industry have yet to fully adopt standardized practices for exchanging BIM and BEM data. This article explores the challe
The UK Hydrogen Strategy (August 2021) and subsequent Heat and Buildings Strategy (October 2021) affirm that a strategic decision is set to be taken by 2026 on the prospect of residential decarbonisation via ‘hydrogen homes’. As this decision date draws nearer, quantitative insights on consumer perceptions of hydrogen-fuelled heating and cooking appliances remain limited. The existing knowledge de
ObjectiveTo evaluate if adding esketamine and clonidine has positive effects on postoperative pain, postoperative nausea and vomiting, and quality of recovery in patients who are at high risk for postoperative pain.DesignPatient- and assessor-blinded, superiority, randomised controlled trial.SettingSingle centre between 2022 and 2024.Patients125 adult patients, ASA I – II, planned for elective lap
Tau hyperphosphorylation, a key neuropathological feature of tauopathies such as Alzheimer’s disease (AD), also occurs physiologically during mammalian hibernation and is fully reversed upon arousal, offering a unique translational model to study tau metabolism. However, limited data exist on insoluble and soluble tau alterations during hibernation and on patterns of tau fragment concentrations in
