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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 193049 hits

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The changes in submicrometer atmospheric particle size distributions measured with a Differential Mobility Particle Sizer (DMPS) system during a polluted fog experiment during November, 1994 are presented in this study. Results reveal three modes commonly evident in the size distribution (3 < DN < 843 nm) measurements; the ultrafine, Aitken and accumulation with respective geometric diameters, (Dg

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In order for manufacturing companies to remain competitive while also offering a high degree of customization for the customers, flexible robots that can be rapidly reprogrammed to new tasks need to be applied in the factories. In this paper we propose a method for the intuitive programming of an industrial mobile robot by combining robot skills, a graphical user interface and human gesture recogn

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Objectives: Gastrointestinal symptoms are common in endometriosis, but the mechanisms behind these symptoms are yet poorly understood. Associations between endometriosis and irritable bowel syndrome (IBS), celiac disease, and various autoimmune diseases have been reported. These diseases express characteristic autoantibodies. The aim of the current study was to investigate autoantibodies against g

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The association between HLA-DQ haplotypes and insulin-dependent diabetes mellitus (IDDM) was studied in 48 children from 44 families ascertained from the high incidence area around Umea, Sweden. Numerous hypotheses have been proposed to explain associations between HLA and IDDM, but comparisons of statistical models based on these hypotheses have not been attempted. The aim of the present study wa

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PURPOSEAPR-246 (PRIMA-1MET) is a novel drug that restores transcriptional activity of unfolded wild-type or mutant p53. The main aims of this first-in-human trial were to determine maximum-tolerated dose (MTD), safety, dose-limiting toxicities (DLTs), and pharmacokinetics (PK) of APR-246. PATIENTS AND METHODSAPR-246 was administered as a 2-hour intravenous infusion once per day for 4 consecutive d

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ALG1-CDG (formerly CDG-Ik) is a subtype of congenital disorders of glycosylation (CDG) where the genetic defect disrupts the synthesis of the lipid-linked oligosaccharide precursor required for N-glycosylation. The initial step in the investigation for these disorders involves the demonstration of hypoglycosylated serum transferrin (TF). There are no specific biomarkers of this CDG subtype known t

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PURPOSE: To determine if the curve length, curve form, and location of the lower-end vertebra can identify the type of scoliosis. METHODS: Standing posteroanterior and lateral radiographs of 78 women and 27 men with scoliosis aged 8 to 32 years were retrospectively analysed. Parameters measured were (1) the curve length (the number of vertebrae in the main curve), (2) the curve form (C-form, inver

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Popular Abstract in Swedish Svensk sammanfattning av avhandlingen: “Social Insurance, Organization and Hospital Care”. Denna avhandling handlar om incitament och organisation. Det inledande kapitlet sammanfattar avhandlingen samt diskuterar relaterad litteratur. Kapitel 2 är ett bidrag till den teoretiska litteraturen kring socialförsäkringar, kapitel 3 behandlar den optimala organisationen av triThis thesis consists of four chapters where chapter 1 introduces the topics in the following chapters and discusses some related literature. Chapter 2 moves beyond the disability insurance with two types, able and disabled, in Parsons (1996). This is done in two ways: by introducing a third type, the partially disabled, and by allowing for a continuum of types. It is assumed throughout that the i

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Previous research has found that stimulating inattentive people with auditory white noise induces enhancement in cognitive performance. This enhancement is believed to occur due to a statistical phenomenon called stochastic resonance, where noise increases the probability of a signal passing the firing threshold in the neural cells. Here we investigate whether people with low attentiveness benefit

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The author shows that the proofs of \n B. H. Arnold\en [Amer. Math. Monthly 56 (1949), 465--466; MR0031725 (11,195h)] and \n I. Niven\en [ibid. 57 (1950), 246--248; MR0035738 (12,4c)] of the fundamental theorem of algebra, based on the Brouwer fixed point theorem, are incomplete. Both Arnold and Niven recognized that the proofs are invalid, and they remarked that no easy remedy seems to save their

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It is an established notion that the silent movies were more international in their character than sound films. The arrival of talkies set up language barriers that often turned into national boundaries for smaller countries like Sweden. However, before this happened the international interaction between mainly European countries and America was vivid, exchanging directors, actors, and importing a

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Popular Abstract in Swedish Det är en viktig uppgift för samhället att förebygga HIV och STI (sexuellt överförbara infektioner) bland ungdomar. Under de första åren av 1990-talet, när denna studie genomfördes, ökade dessa infektioner på ett oroväckande sätt. Detta gällde särskilt klamydiainfektionerna och nästan 25% av studenterna vid Lunds universitet rapporterade att de hade haft en konstaterad Slowing the incidence of HIV and STI among young people requires that they change their sexual behaviours. There is evidence that community-based interventions that target multiple levels of influence can be effective. In community mobilization different segments and sectors of a population are directly involved in problem identification and in the design and implementation of programs. The proces

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Can we be mistaken or ignorant about the meaning of our own words? This dissertation explores this question. More specifically it investigates to what extent and in what sense, if at all, the semantic meaning of religious and existentially important words – like ‘God’, ‘friendship’, ‘justice’ or ‘life’ – can be recognition-transcendent to the competent user of them. The possibility of words having

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Decentralized Cloud Storage (DCS) is considered to be the future for sustainable data storage within Web 3.0, in which we will move from a single cloud service provider to creating an ecosystem where anybody could be a cloud storage provider. Currently, the cloud storage market is highly dominated by centralized players like Amazon S3, Google Cloud, Box, etc. Decentralized projects like Storj, Fil

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Background: Remaining pain and functional limitations may cause dissatisfaction in patients after total knee arthroplasty (TKA). Furthermore, anxiety and depression are associated with remaining postoperative symptoms and dissatisfaction. We investigated if patient-reported anxiety or depression increased the risk of dissatisfaction 1 year after TKA in patients who improved in pain or function. Me