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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 114882 hits

Experimental studies of sorption and transport of moisture in cement based materials with supplementary cementitious materials

Most deterioration processes in cement based materials are closely related to moisture sorption and moisture transport properties. Therefore, it is important to study these properties, both theoretically and practically. This work is an experimental investigation in this field. Nowadays, the cement industry produces cements with increasing amounts of supplementary cementitious materials (SCMs) to

Key Performance indicators used as measurement parameter for plant-wide feedback loops - work in progress

Feedback is a fundamental concept in automatic control. Feedback loops are used extensively in industrial applications today and there are work-procedures for designing traditional single parameter control loops. In the work procedure it is important to select control-parameters, manipulated parameters and control-strategies. A similar work-procedure could also be used for designing plant-wide con

The solar map as a knowledge base for solar energy use

Our existing urban environment has a significant potential to increase the use of renewable energy, mainly by using solar irradiation for heat and electricity. Quantification of the solar potential by means of a solar map is the first step in the acceleration process for using more solar energy in our urban environments. A solar map is a GIS system providing the annual solar irradiation on buildin

Characterization of molecularly imprinted polymer nanoparticles by photon correlation spectroscopy

We follow template-binding induced aggregation of nanoparticles enantioselectively imprinted against (S)-propranolol, and the non-imprinted ones, using photon correlation spectroscopy (dynamic light scattering). The method requires no separation steps. We have characterized binding of (R,S)-propranolol to the imprinted polymers and determined the degree of non-specificity by comparing the specific

Identification of Late-Onset Hypogonadism in Middle-Aged and Elderly Men

BACKGROUND The association between aging-related testosterone deficiency and late-onset hypogonadism in men remains a controversial concept. We sought evidence-based criteria for identifying late-onset hypogonadism in the general population on the basis of an association between symptoms and a low testosterone level. METHODS We surveyed a random population sample of 3369 men between the ages of 40

No clinical benefits using a new design of pins for external fixation: a randomized study in 50 patients operated on by the hemicallotasis technique.

BACKGROUND: Pin-site infection and pin loosening are complications that can cause discomfort to the patients. The purpose of present study was to evaluate pin-site infection, pain, and the use of medications using the XCaliber pin (Orthofix) with optimized thread and tip design, and the commonly used standard pin (Orthofix) during the procedure of hemicallotasis osteotomy (HCO). MATERIAL AND METHO

Hyperproinsulinemia segregates young adult patients with newly diagnosed autoimmune (type 1) and non-autoimmune (type 2) diabetes

Objective. To investigate whether measurements of proinsulin and/or intermediate proinsulin degradation products could be used to differentiate between autoimmune (type 1) and non-autoimmune (type 2) diabetes in young adults. Material and methods. Total proinsulin, intact proinsulin and 32,33 split proinsulin concentrations were measured in 25 patients aged 15-34 years with type 1 diabetes, as def

To Have and to Hold: Continuity and change in property rights institutions governing water resources among the Meru of Tanzania and the BaKgatla in Botswana; 1925-2000

Allocation, control, and management of natural resources are issues that absorb researchers within both the social and natural sciences. This study deals with such research questions as well as with one of the most fundamental issues in Economic History – namely institutional change. The plot is set around continuity and change of property rights institutions governing water resources. The setting

Distribution and Function of Cannabinoid Receptors 1 and 2 in the Rat, Monkey and Human Bladder

Purpose: We investigated the distribution of cannabinoid receptor subtypes 1 and 2 in the detrusor of different species and studied the effects of cannabinoid receptor 1 and 2 agonists on bladder function. Materials and Methods: Cannabinoid receptor 1 and 2 expression was studied with Western blot and immunohistochemistry in rat, monkey and human detrusors. Co-staining was done for markers of sens

PACAP and orphanin FQ/nociceptin -Distribution, importance and regulation in sensory neurons and spinal cord

Popular Abstract in Swedish Information om vår omvärld förmedlas med hjälp av elektriska och kemiska signaler i kroppens olika nervbanor till hjärnan där vi tolkar signalerna. Dessa s.k. sensoriska signaler förmedlar information om så skilda saker som hur maten smakar till hur varmt det är, hur ett föremål ser ut, känns osv, till smärtinformation som hjälper oss att undvika farliga situationer. I Neuropeptide expression in the nervous system is abundant and plastic, and an altered expression after injury is an example of a functional response, helping the neuron to cope with adverse changes, and involves effects on differentiation, synthesis, repair/regeneration, survival, and modulation of signal transmission. I have investigated the distribution/expression of the neuropeptides, orphanin

Studies on Peripheral Nerve Regeneration: Microdispensing, Neurite Guidance and Galectins

The present thesis describes development of a microdispenser-based technique to create of protein patterns for neurite guidance. The same technique was also developed to allow direct positioning of dissociated cells, including neurons, on cell culture substrates. Finally the role of galectin-3 and 8 during nerve regeneration was investigated. The thesis consists of four papers (I-IV). Microdispen

The Victorian Governess Novel

The governess held a peculiar position in Victorian England: she was a wage-earning, middle-class woman in a society in which middle-class femininity was defined by domesticity and non-participation in the public labour market. This made her a suitable heroine for writers focusing on domestic, educational and social issues. This study investigates the Victorian governess novel as a specific genre

Pipeline break detection using pressure transient monitoring

Sudden pipe breaks occur in water transmission pipelines and distribution mains. The consequences of these breaks can be very expensive because of the service interruption, the cost of repair, and damage to surrounding property and infrastructure. The costs associated with the pipeline breaks can be reduced by minimizing the break detection and location time. This paper presents a new continuous m

Acupuncture and transcutaneous nerve stimulation in stroke rehabilitation: a randomized, controlled trial

BACKGROUND AND PURPOSE: In small trials with control groups that receive no intervention, acupuncture has been reported to improve functional outcome after stroke. We studied effects of acupuncture and transcutaneous electrical nerve stimulation on functional outcome and quality of life after stroke versus a control group that received subliminal electrostimulation. METHODS: In a multicenter rando