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BACKGROUND: Irritable bowel syndrome (IBS) is the major form of functional bowel disorders, where the diagnosis is based on set criteria and characterized by abdominal pain and changes in bowel habits. Epidemiological data, alongside self-reported outcomes, are of interest with regard to IBS, as these factors may need to be addressed to optimize underlying IBS. This study aims to examine the effec
We study the magnetic Laplacian in a two-dimensional exterior domain with Neumann boundary condition and uniform magnetic field. For the exterior of the disk we establish accurate asymptotics of the low-lying eigenvalues in the weak magnetic field limit. For the exterior of a star-shaped domain, we obtain an asymptotic upper bound on the lowest eigenvalue in the weak field limit, involving the 4-m
To Alan Walmsley, at sixty-fiveJarash (also Jerash, Greek Gerasa) ranks among the principal urban centres of Late Antique and Early Islamic Jordan. Despite being one of the most intensively investigated urban sites within the region, the history of Jarash during the Islamic ages, in particular after the massive earthquake of 749, remains a topic of profound disagreement. Drawing on previously unpu
We report on the discovery and spectroscopic confirmation of TOI-2458 b, a transiting mini-Neptune around an F-type star leaving the main-sequence with a mass of M∗ = 1.05 ± 0.03 M⊙, a radius of R∗ = 1.31 ± 0.03 R⊙, an effective temperature of Teff = 6005 ± 50 K, and a metallicity of 0.10 ± 0.05 dex. By combining TESS photometry with high-resolution spectra acquired with the HARPS spectrograph, we
An additional upsurge in bacterial STIs has been observed in Sweden following HIV pre-exposure prophylaxis (PrEP) implementation. From a prevention perspective, it is of relevance to optimize testing strategies within PrEP programmes to identify those most at risk. An open retrospective longitudinal observational cohort study was performed at three STI clinics in Uppsala, Gothenburg, and Malmö. A
This thesis explores the challenges and advancements in high-dimensional Bayesian optimization (HDBO), focusing on understanding, quantifying, and improving optimization techniques in high-dimensional spaces.Bayesian optimization (BO) is a powerful method for optimizing expensive black-box functions, but its effectiveness diminishes as the dimensionality of the search space increases due to the cu
Songbird migration involves frequent migratory flights interrupted by several days of stopover to refuel. For first-year migratory birds, this entails stopping in unfamiliar locations to exploit local resources and maximise fuelling rates. However, stopovers also pose mortality risks due to predator presence. We aimed to determine whether auditory cues from avian predators with differing hunting s
The membranous ER spans the entire cell, creating a network for the biosynthesis of proteins and lipids, cell-wide communication, and nuclear delivery of molecules, including therapeutic agents. Here, we identify a novel ER response triggered by the tumoricidal complex alpha1-oleate, defined by a loss of peripheral ER structure, extensive ER vesiculation. Alpha1-oleate was present in the ER-derive
Albeit costly, flight allows birds to travel great distances in a short time, making it a highly effective mode of locomotion, especially during migration.1,2 Understanding how birds use energy during flight is essential for studying their flight ecology.3 To fly, birds flap their wings, accelerating surrounding air and generating flight forces, where the rate of energy added to the wake represent
Particle exchange heat engines are a novel class of cyclic heat engines that are all-electrical, contain no moving parts and can therefore be scaled down to nanometer size. At the center of their operation is the manipulation of a particle flow between a hot and a cold reservoir through energy filtering mechanisms, where their efficiency depends primarily on the sharpness of the energy filter. In
The maintenance of variation (i.e., different phenotypes) for heritable traits that are under selection, despite expectations of selection eroding variation and favouring only the fittest phenotype, represents an evolutionary paradox. Here, we studied variation in life-history traits in five populations of colour polymorphic tawny owls (Strix aluco) across Europe that have been individually studie
BACKGROUND: The COVID-19 vaccination campaign in several European countries involved collaboration between public health and Primary Health Care (PHC). OBJECTIVE: To highlight the role of PHC professionals in the COVID-19 vaccination rollout, specifically in terms of vaccine administration, communication and contributing to vaccination population coverage. METHODS: A descriptive retrospective stud
Electrodialysis is a water desalination technology that enables selective separation of ions, making it a promising solution for sustainable water reuse. The selectivity of the process is mainly determined by the properties of ion exchange membranes that can vary depending on the composition of ions in water, such as water uptake and charge density. In this work, we studied selective adsorpti
Marketing is an important function and practice in everyday business. It involves getting potential customers interested in a product or service through value-oriented arguments. In this way, marketing plays a pivotal role in driving the consumption of goods and services. Given the increasing consumption of goods and services, decreasing product lifetimes, and increasing levels of waste in all pro
