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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 193054 hits

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This research investigates the daylight regulation compliance of existing multi-family housing developments located primarily in Stockholm (Lat.: 59,33 °N), Sweden. A representative sample of 54 buildings consisting of 10.888 individual rooms was modelled according to archived documentation drawings and evaluated by use of Radiance simulations, to test their compliance with the current Swedish day

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A mononuclear iron(II) complex [FeII(N4PyMe2)(OTf)](OTf)(1), supported by a new pentadentate ligand, bis(6-methylpyridin-2-yl)-N,N-bis((pyridin-2-yl)methyl)methanamine (N4PyMe2), has been isolated and characterized. Introduction of methyl groups in the 6-position of two pyridine rings makes the N4PyMe2 a weaker field ligand compared to the parent N4Py ligand. Complex 1 is high-spin in the solid st

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While the role played by the state in stimulating innovation in the private sector has been a prevalent interest in innovation research, studies analysing the impacts of public interventions have usually focused on individual policies, programs or projects. Public stimulation is hence often studied from a relatively restricted and temporarily confined perspective, leaving a macro-level and longer-

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It is well known that nature offers an abundance of materials and processes that can be adapted in low-tech fashion, to fabricate systems capable of removing pollutants from wastewater. During the last decade, extensive basic and engineering research on such natural treatment systems have led to improvement of the quality of discharged wastewaters. However, the mechanisms of natural treatment and

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Background/Objectives A cascade of gene activations under the control of Notch signalling is required during T-cell specification, when T-cell precursors gradually lose the potential to undertake other fates and become fully committed to the T-cell lineage.We elucidate how the gene/protein dynamics for a core transcriptional module governs this important process by computational means. Methods We

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We consider multistep discretizations, stabilized by β-blocking, for Euler-Lagrange DAEs of index 2. Thus we may use “nonstiff” multistep methods with an appropriate stabilizing difference correction applied to the Lagrangian multiplier term. We show that order p =k + 1 can be achieved for the differential variables with order p =k for the Lagrangian multiplier fork-step difference corrected BDF m

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Anthropologists have generally found it reasonable to understand the Industrial Revolution in Britain as a product of global historical processes including colonialism and the structure of world trade. The extent to which the industrialization of British textile production was contingent on global processes has been illuminated in detail by historians such as Joseph Inikori. Andre Gunder Frank pro

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Plant cells integrate signals from external sources and from organelles to regulate gene expression, referred to as anterograde and retrograde signaling, respectively. Functional characterization of the promoter of ALTERNATIVE OXIDASE1a (AOX1a) from Arabidopsis (Arabidopsis thaliana), a marker for mitochondrial retrograde response, was carried out by testing the ability of the AOX1a promoter to dr

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The cluster of pathologies comprising the metabolic syndrome (MetS) includes increased waist circumference, hyperglycemia, elevated blood pressure and hyperlipidemia. With time, these conditions present a major risk of developing obesity, type 2 diabetes and atherosclerosis. Fecal microbiota transplant (FMT) experiments performed in mice have given an intriguing foundation for a microbial-based th

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This paper discusses the effects of cooled EGR on a turbocharged multi-cylinder HCCI engine. A six-cylinder, 12-liter, Scania D12 truck engine is modified for HCCI operation. It is fitted with port fuel injection of ethanol and n-heptane and cylinder pressure sensors for closed-loop combustion control. The effects of EGR are studied in different operating regimes of the engine. During idle, low sp