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Corynebacterium sp. (ATCC 21245) is reclassified here as Mycobacterium sp. MS1601 based on 16S rRNA gene and complete-genome sequence analysis. It is able to oxidize branched polyols to corresponding hydroxycarboxylic acids. The total size of the genome sequence was 6,829,132 bp, including one circular chromosome of 6,407,860 bp.
Background Little is known about how pharmaceutical companies lobby authorities or experts regarding procurement or the use of vaccines and antivirals. This paper investigates how members of Denmark's pandemic planning committee experienced lobbying efforts by Roche, manufacturer of Tamiflu, the antiviral that was stockpiled before the 2009 A(H1N1) pandemic. Methods Analysis of interviews with six
High blood glucose triggers the release of insulin from pancreatic beta cells, but if chronic, causes cellular stress, partly due to impaired Ca2+ homeostasis. Ca2+ influx is controlled by voltage-gated calcium channels (CaV) and high density of CaV in the plasma membrane could lead to Ca2+ overload. Trafficking of the pore-forming CaVα1 subunit to the plasma membrane is regulated by auxiliary sub
The exact biosynthetic pathways leading to benzoic acid (BA) formation in plants are not known, but labeling experiments indicate the contribution of both beta-oxidative and non-beta-oxidative pathways. In Petunia hybrida BA is a key precursor for the production of volatile benzenoids by its flowers. Using functional genomics, we identified a 3-ketoacyl-CoA thiolase, PhKAT1, which is involved in t
The load capacity of long adhesive lap joints is often governed by stress concentrations at the lap ends. This paper investigates a method to minimize these stress concentrations by using a bond line with low shear stiffness and sufficient strength, here denoted as a resilient bond line. The resilient bond line is intended to increase the load carrying capacity of long lap joints by achieving a mo
Species integrity can be challenged, and even eroded, if closely related species can hybridize and produce fertile offspring of comparable fitness to that of parental species. The maintenance of newly diverged or closely related species therefore hinges on the establishment and effectiveness of pre- and/or post-zygotic reproductive barriers. Ecological selection, including predation, is often pres
PurposePREPL deficiency causes neonatal hypotonia, ptosis, neonatal feeding difficulties, childhood obesity, xerostomia, and growth hormone deficiency. Different recessive contiguous gene deletion syndromes involving PREPL and a variable combination of SLC3A1 (hypotonia-cystinuria syndrome), CAMKMT (atypical hypotonia-cystinuria syndrome), and PPM1B (2p21 deletion syndrome) have been described. In
Obesity is a major health problem, and although caloric restriction and exercise are successful strategies to lose adipose tissue in obese individuals, a simultaneous decrease in skeletal muscle mass, negatively effects metabolism and muscle function. To deeper understand molecular events occurring in muscle during weight-loss, we measured the expressional change in human skeletal muscle following
The purpose of this article is to contribute to the discussion concerning the present position and future directions of strategic communication by look- ing into the past and offering some proposals and a vision of how to develop and advance the field further. Research in strategic communication has mostly focused on communication professionals working in commu- nication departments or agencies as
An account of the Stockholm Film Workshop (1973 - 2001) and how it became a site of film production by immigrant filmworkers, primarily from Latin America and Greece.
Diesel engines are by far the most common means of propulsion aboard ships. It is estimated that around half of their fuel energy consumption is dissipated as low-grade heat. The organic Rankine cycle technology is a well-established solution for the energy conversion of thermal power from biomass combustion, geothermal reservoirs, and waste heat from industrial processes. However, its economic fe
Hybridization is increasingly recognized as a potent evolutionary force. Although additive genetic variation and novel combinations of parental genes theoretically increase the potential for hybrid species to adapt, few empirical studies have investigated the adaptive potential within a hybrid species. Here, we address whether genomic contingencies, adaptation to climate, or diet best explain dive
Analysing the historiography of early to mid 20th century monumental painting in Sweden, the article argue that this historiography is characterised by a recurring interest of unactualised avant-garde proposals for public art (many of them preserved as sketches at Skissernas Museum – Museum of Artistic Process and Public Art in Lund). Sketches for these proposals are set forward as key monuments i
Both research and policy recognize land systems as fundamental to human life and activities. However, these two perspectives approach land from different ends and it can be difficult to see how studied variables contribute to broader policy goals. In this paper, we argue that there is a need to better select variables to study land systems as social-ecological systems, and to align research more w
OBJECTIVE: The Diabetes Prevention Program (DPP) trial investigated rates of progression to diabetes among adults with prediabetes randomized to treatment with placebo, metformin, or intensive lifestyle intervention. Among women in the DPP, diabetes risk reduction with metformin was greater in women with prior gestational diabetes mellitus (GDM) compared with women without GDM but with one or more
Background: The industrially important yeast Blastobotrys (Arxula) adeninivorans is an asexual hemiascomycete phylogenetically very distant from Saccharomyces cerevisiae. Its unusual metabolic flexibility allows it to use a wide range of carbon and nitrogen sources, while being thermotolerant, xerotolerant and osmotolerant. Results: The sequencing of strain LS3 revealed that the nuclear genome of
BACKGROUND: The FORS histo-blood group system was described in 2013 and much remains to be investigated regarding its genetic and immunohematologic characteristics, as well as its clinical importance. While presence of the c.887G>A-mutated GBGT1 gene, which results in FORS1 glycosphingolipid expression on human red blood cells (RBCs), is rare in the populations tested so far, naturally occurring a
