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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 193096 hits

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Social role theory posits that binary gender gaps in agency and communion should be larger in less egalitarian countries, reflecting these countries’ more pronounced sex-based power divisions. Conversely, evolutionary and self-construal theorists suggest that gender gaps in agency and communion should be larger in more egalitarian countries, reflecting the greater autonomy support and flexible sel

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The influence of aeration diffuser system design on electricity usage, effluent water quality, and life-cycle cost in biological wastewater treatment was investigated. A plant-wide model was implemented, and simulations were carried out with different process configurations and aeration systems. Model-aided design of new aeration diffuser systems could significantly decrease electricity usage and

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There is a general consensus that private car ownership is a significant barrier to transport system change, specifically in regard to injuries, space, air pollutants, or greenhouse gas emissions. Observed changes in automobile characteristics also suggest that the system is becoming less sustainable, given trends towards larger cars with greater mass and horsepower. It is thus relevant to underst

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Calculations of two-dimensional unsteady flow around a quadratic two-dimensional cylinder at zero angle of attack are performed. The Reynolds numbers are low (Re = 45 - 250) so that the flow presumably is laminar. At Re > 50 a von Karman vortex street with a well-defined shedding frequency is predicted. An incompressible SIMPLEC finite volume code employing non-staggered grid arrangement is used.

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A novel test method was used to study the concentration and size distribution of airborne wear particles from disc brake materials. A pin-on-disc tribometer equipped with particle counting instruments was used as test equipment. Material from four different non-asbestos organic (NAO) pads and four different low metallic (LM) pads were tested against material from grey cast iron rotors. The results

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H-infinity optimal control and estimation are addressed for a class of systems governed by partial differential equations with bounded input and output operators. Diffusion equations are an important example in this class. Explicit formulas for the optimal state feedback controller as well as the optimal state estimator are given. Unlike traditional methods for H-infinity synthesis, no iteration i

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The purpose of this presentation/paper is to contribute to a deeper understanding of the infinite number of experiences of what it is to learn to play a musical instrument. By providing a theoretical platform to visualise and discuss these experiences, the aim is further to support the posing of questions regarding the future of teaching and learning music across all ages, genres and levels of exp

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This paper presents a numerical model designed to simulate subaqueous cross-shore profile behavior, including response of feeder mounds and barred systems. The present model development builds on the semi-empirical model proposed by Larson et al. (2013), designed to simulate the evolution of longshore bars exposed to incident waves, as well as the exchange of material between the bar and the berm

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BACKGROUND: The overall incidence of colorectal carcinoma is declining in Western populations; however, single country series demonstrate an increase in young-onset (<50 years) colorectal carcinoma. OBJECTIVE: The purpose of this study was to determine whether the pattern of increasing incidence of young-onset colorectal carcinoma is consistent across 3 Western populations. DESIGN: This is a popul

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Background: Currently, hand-held gamma cameras are being developed for 99mTc imaging, mainly for sentinel lymph node detection. These cameras offer advantages, such as mobility and ease of access, and may be useful also for other applications such as biokinetic studies in animals or for imaging of small, superficial structures in patients. In this work, the suitability of a CZT-based hand-held cam

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Monarchy was the dominant form of rule in the pre-modern era and it persists in a handful of countries. We propose a unified theoretical explanation for its rise and decline. Specifically, we argue that monarchy offers an efficient solution to the primordial problem of order where societies are large and citizens isolated from each other and hence have difficulty coordinating. Its efficiency is ch

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Several climate oscillations have been reported from the early Holocene superepoch, the best known of which is the Preboreal oscillation (PBO). It is still unclear how the PBO and the number of climate oscillations observed in Greenland ice cores and European terrestrial records are related to one another. This is mainly due to uncertainties in the chronologies of the records. Here, we present new

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Litigation involving individuals and entities whose financial assets have been frozen and whose names have been blacklisted in the fight against terrorism is on the rise around the world. However, the global ‘securitization’ of terrorism has rendered court performance of judicial review and the provision of remedies in these cases more difficult. What the main judicial challenges are, the need to

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Prediction of the service lifetime of concrete structures with respect to chloride ingress involves a number of parameters that are associated with large uncertainties. Hence, full-scale measurements are strongly in demand. This paper begins by summarizing statistical distributions based on measurements taken from the Gimsøystraumen Bridge in Norway. A large number of chloride profiles are availab

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The damping ratio is a key performance measure in systems that can be modelled as networks of masses and springs. We derive a lower bound on this quantity that applies to such networks when the masses are subject to viscous damping. The result allows the size of the damping ratio to be understood as a function of the system parameters. We use this to derive a decentralised criterion which, if sati

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One feature of global change is that biota must respond not to single, but to multiple environmental drivers. By growing a model photosynthetic microbe in environments containing between one and eight different drivers, including changes in CO 2, temperature, and pH, in different combinations, we show that the number as well as the identities of drivers explain shifts in population growth rates. T

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Context: The changes that are taking place with respect to environmental sensitivity are forcing organizations to adopt a new approach to this problem. Implementing sustainability initiatives has become a priority for the social and environmental awareness of organizations that want to stay ahead of the curve. One of the business areas that has, more than others, proven to be a vital asset and a p