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We present here a family with a clinical phenotype resembling Marfan syndrome (MFS), and displaying joint contracture and episodes of knee joint effusions, but lacking the cardiovascular features of the syndrome. The phenotype of this family represents a unique mixture of connective tissue symptoms, some of which are found in classical MFS and some of which are typical of dominant ectopia lentis.
Background: Speech impairments are an early feature of Alzheimer’s disease (AD) and consequently, analysing speech performance is a promising new digital biomarker for AD screening. Future clinical AD trials on disease modifying drugs will require a shift to very early identification of individuals at risk of dementia. Hence, digital markers of language and speech may offer a method for screening
Background: Techniques for autofluorescence have been introduced to visualize the parathyroid glands during surgery and to reduce hypoparathyroidism after thyroidectomy. Methods: This parallel multicentre RCT investigated the use of Fluobeam® LX to visualize the parathyroid glands by autofluorescence during total thyroidectomy compared with no use. There was no restriction on the indication for su
A search for resonances in events with at least one isolated lepton (e or μ) and two jets is performed using 139 fb −1 of s = 13 TeV proton–proton collision data recorded by the ATLAS detector at the LHC. Deviations from a smoothly falling background hypothesis are tested in three- and four-body invariant mass distributions constructed from leptons and jets, including jets identified as originatin
Gastrointestinal stromal tumors (GISTs) are predominantly initiated by KIT mutations. In this study, we observed that discoidin domain receptors 1 and 2 (DDR1 and DDR2) exhibited high expression in GISTs, were associated with KIT, and enhanced the activation of both wild-type KIT and primary KIT mutants. Inhibition of DDR1/2 led to a reduction in the activation of KIT and its downstream signaling
The relatively new and complex field of cybersecurity policy has introduced significant challenges for the EU. The policy area has not yet developed into a coherent one, and it balances security policy with the internal market policy. This study analyses how the Member States use the Council of the EU to forward their interests and preferences in reaction to the evolving policy area. Member States
Titel: Ny information, samma beslut? - En studie av långivares beslutsprocess, med fokus på implementeringen av IFRS 16. Seminariedatum: 5 juni 2019 Kurs: FEKH69, Examensarbete i redovisning på kandidatnivå, 15 högskolepoäng. Författare: Fredrik Blomqvist, Gustaf Bonde & Patrik Lundin Handledare: Kristina Artsberg Fem nyckelord: Leasing, Informationsanvändning vid kreditbedömning, Brunswi
Abstract Introduction: This paper aims to explore the alignment of managerial competencies in higher education and the labor market by conducting a Case Study on the MSc in Management (MiM) at Lund University School of Economics and Management (LUSEM). Method: Managerial competencies were identified through content analysis in entry-level management job advertisements in the Swedish Öresund regi
The EES, Lisbon and Europe 2020 are the most relevant soft law strategies promoting the improvement of work-family reconciliation-related policies in the EU Member States. In this study, the cases of the German Elterngeld reforms are applied to scrutinise the influences of these three strategies on domestic policy-making. Thus, this research work is based on the theoretical framework of soft Europ
In the summer of 2014, about one million Iraqis were forced into internal displacement in the Kurdistan Region of Iraq (KR-I) following successful incursions of the Islamic State of Iraq and the Levant into bordering areas. To mobilize assistance and respond to the immense humanitarian needs, the UN assigned the situation its highest level of emergency, L3. This thesis investigates the emergency r
Objectives: To study effects of the introduction of pneumococcal conjugate vaccines (PCV) on the interspecies dynamics of Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis in preschool children with respiratory tract infection. Methods: Nasopharyngeal samples from children aged ≤6 years with upper respiratory tract infection (n = 14 473) in South Sweden were analysed durin
BACKGROUND: Although tuberculosis accounts for the highest mortality from a bacterial infection on a global scale, questions persist regarding its origin. One hypothesis based on modern Mycobacterium tuberculosis complex (MTBC) genomes suggests their most recent common ancestor followed human migrations out of Africa approximately 70,000 years before present. However, studies using ancient genomes
The present reasoned bibliography was published in Swedish in 1990 as part of a series of reports issued by Linköping University, Arbetsrapporter från Tema Kommunikation, as number 1990:4 in the series. It gained some diffusion among history of photography specialists in the Nordic countries, but was never printed. In the thirty years that have passed since then, no new and comprehensive reasoned
Atopic dermatitis (AD) is a disease that can have a high impact on quality of life, especially due to itch and skin pain. This paper utilizes expertise from members of the International Society of Atopic Dermatitis (ISAD)/Oriented Patient-Education Network in Dermatology (OPENED) task force to review the epidemiology, pathophysiology and exacerbating factors of itch and pain in atopic dermatitis.
The superhero was created during the great depression. Their adventures captivated their young readers and it was not long until they found their way into other media. I have noticed that during the last ten years there has been an increase of the production of superhero movies. I will during my essay bring up major events that have had an impact on the movie industry and analyze what different
This thesis examines the role of visual media in conveying the Gallic founding myth and constructing national identity in nineteenth-century France. Positioned at the interdisciplinary intersection of nationalism studies and memory research, it investigates how visual representations embed the Gallic founding narrative – despite its association with military defeat – into France’s collective memor
Background: Adrenaline (ADR) is a cornerstone of advanced life support (ALS) in cardiac arrest (CA), although its neurologically favourable survival outcomes remain unclear. ADR increases coronary perfusion pressure (CPP), with levels >15 mmHg associated with successful defibrillation. This study aimed to elucidate the relationship between ADR, myocardial microvascular blood flow, and resuscitatio
Microplastics are increasingly recognized as a pervasive pollutant in both aquatic and terrestrial environments, raising pressing concerns about their ecological impacts and implications for human health. Traditional detection and quantification methods—including manual microscopy and standalone spectroscopic techniques—offer reliable accuracy but are limited by labor-intensive procedures and low
