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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 192207 hits

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This paper contributes to understanding national variations in using low-carbon electricity sources by comparing the evolution of nuclear, wind and solar power in Germany and Japan. It develops and applies a framework for analyzing low-carbon electricity transitions based on interplay of techno-economic, political and socio-technical processes. We explain why in the 1970s–1980s, the energy paths o

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Solar energy is considered to be an alternative sustainable energy source in the urban environment. The potential of using solar energy in urban areas is highly dependent on urban morphology which affects the level of solar irradiance received by individual buildings. Many studies focus on solar energy potential of building form in urban areas but relatively few studies examine how urban morpholog

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During the 1970s, pornographic magazines that envisioned the Finnish man sovereignly enjoying sexual pleasures in Eastern Europe, the Soviet Union, the Middle East, and the Far East became extremely popular in Finland. In this article it is argued that pornographic magazines functioned as geographical as well as sexual maps; through the medium of magazines, Finnish readers were educated to think o

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Objective: To describe the anatomy of uterine lymphatic drainage following cervical or fundal tracer injection to enable standardization of a pelvic sentinel lymph node (SLN) concept in endometrial cancer (EC). Methods: A prospective consecutive study of women with EC was conducted. A fluorescent dye (Indocyanine green) was injected into the cervix (n = 60) or the uterine fundus (n = 30). A system

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We reanalyze the recent multilab preregistered study on ego-depletion by Hagger and Chatzisarantis (2016) as if their data were obtained under the research program-strategy (Witte & Zenker, 2016a, 2016b). This strengthens Hagger and Chatzisarantis’s (2016) main conclusion, because our reanalysis more directly corroborates the absence of a medium-sized, or a small-sized, ego-depletion effect (d

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The entrepreneurial ecosystem (EE) literature has attracted much attention, especially in policy circles. However, the concept suffers from a number of shortcomings: (1) it lacks a clear analytical framework that makes explicit what is cause and what is effect in an EE; (2) while being a systemic concept, the EE has not yet fully exploited insights from network theory, and it is not always clear i

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A swirl stabilized gas turbine burner has been simulated in order to assess the effects of the fuel properties on spray dispersion and fuel-air mixing. The properties under consideration include fuel surface tension, viscosity and density. The turbulence of the gas phase is modeled applying the methodology of large eddy simulation whereas the dispersed liquid phase is described by Lagrangian parti

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Objective: To explore the association between administration-to-birth interval of antenatal corticosteroids (ACS) and survival in extremely preterm infants. Design: Population-based prospective cohort study. Setting: All obstetric and neonatal units in Sweden from 1 April 2004 to 31 March 2007. Population: All live-born infants (n = 707) born at 22-26 completed weeks of gestation. Methods: The rel

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Rare cells in blood, such as circulating tumor cells or fetal cells in the maternal circulation, posses a great prognostic or diagnostic value, or for the development of personalized medicine, where the study of rare cells could provide information to more specifically targeted treatments. When conventional cell separation methods, such as flow cytometry or magnetic activated cell sorting, have fa

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Heavy-metal homeostasis and detoxification is crucial for cell viability. P-type ATPases of the class IB (PIB) are essential in these processes, actively extruding heavy metals from the cytoplasm of cells. Here we present the structure of a PIB-ATPase, a Legionella pneumophila CopA Cu(+)-ATPase, in a copper-free form, as determined by X-ray crystallography at 3.2 Å resolution. The structure indica

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What are the pedagogical impacts of internationalisation on the development of higher education in Europe? How can we proceed in this process and take a pedagogical stance on the issue? This theoretical article is partly based on a series of empirical studies, conducted by the author, investigating students' and teachers' experiences and understanding of an internationalised educational context in

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A detailed analysis of the classic Stern-Gerlach experiment is presented. An analytical simple solution is presented for the quantum description of the translational and spin dynamics of a silver atom in a magnetic field with a gradient along a single z-direction. This description is then used to obtain an approximate quantum description of the more realistic case with a magnetic field gradient al

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In order to explore consumer culture’s potential to change social relations, this investigation immerses into the growing consumer culture of foodies occupying the historically feminine space of domestic cooking. It offers a tentative theory on the entering of subordinate consumption fields in contexts where the entering is sanctioned by cultural authorities.

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Gasoline partially premixed combustion (PPC) has shown potential in terms of high efficiency with low emissions of oxides of nitrogen (NOx) and soot. Despite these benefits, emissions of unburned hydrocarbons (UHC) and carbon monoxide (CO) are the main shortcomings of the concept. These are caused, among other things, by overlean zones near the injector tip and injector dribble. Previous diesel lo