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Your search for "Identification of severity related mutation hotspots in SARS-CoV-2 using a density-based clustering approach" yielded 195742 hits

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The interactions between uncharged polymers, e.g. ethyl(hydroxylethyl)cellulose (EHEC) and some model polymers, and ionic surfactants in aqueous solution has been studied by using isothermal titration and differential scanning calorimetry. We found that titration calorimetry could give quite detailed information about polymer - surfactant interactions. Values for the critical aggregation concentra

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It is easy when studying the literature on the current development toward closer more integrated business to business relationships to get the impression that a close integrated relationship is desired for all circumstances. Instead, this thesis shows that the nature of business relationship is very strongly correlated to product supplied. The focus of this thesis has been a case study between a s

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The focus of this article has been to analyse the machinability, with focus on surface integrity, of oxygen-free copper (OFC) and niobium during turning operations. The results from machining OFC proved that all of the tools that was tested can be used to achieve a surface roughness below Ra = 0.8 µm with the correct cutting data. From the results when machining niobium it showed that only the cem

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Who can pick a winner? Since 1974, various types of targeted support have at different times been directed at the development of the heat pump market in Sweden – which in the following decades oscillated violently between soaring sales and collapse. Eventually, however, small heat pumps for space heating of residential buildings have in recent years securely established themselves as a mature and

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This paper verified the macro-to-mini-scale criterion BoRe10.5=200 because data points where BoRe10.5≤200 and BoRe10.5>200 show very different trends for the entire database (1672 data points). Boiling number at critical heat flux (Blchf) decreases greatly with heated length-to-diameter ratio (Lh/dhe) when Lh/dhe is small while a relatively smooth trend occurs with large Lh/dhe values. The paper p

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A single-nucleotide polymorphism (SNP) at the IL12RB2 locus showed a suggestive association signal in a previously published genome-wide association study (GWAS) in systemic sclerosis (SSc). Aiming to reveal the possible implication of the IL12RB2 gene in SSc, we conducted a follow-up study of this locus in different Caucasian cohorts. We analyzed 10 GWAS-genotyped SNPs in the IL12RB2 region (2309

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To investigate the effectiveness of powered mobility device (i.e. powered wheelchair and scooter) interventions over a one year period in the Nordic context.

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During the last few decades, ideas of empowerment, person-centred care (PCC) and shared decision-making (SDM) have informed western health care. An increasing interest in conversational styles aligned with these ideas is visible e.g. in the work to make motivational interviewing (MI) an evidence-based communicative practice. But linguistic competence is needed to identify the subtle nuances of the

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A review is presented for two-phase modeling approaches to study various transport processes and reactions in polymer electrolyte membrane (PEM) fuel cells along with some experimental work. It has been noted that water management is still one of the least accurate modeled phenomena. The lackness in complete descriptive models for water management inside PEM fuel cells can be attributed to the com

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Human tumors xenografted in immunodeficient mice are crucial models in nuclear medicine to evaluate the effectiveness of candidate diagnostic and therapeutic compounds. However, little attention has been focused on the biological profile of the host model and its potential effects on the bio-distribution and tumor targeting of the tracer compound under study. We specifically investigated the dissi

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The theory of island biogeography is most often studied in the context of oceanic islands where all island inhabitants are descendants from founding events involving migration from mainland source populations. Far fewer studies have considered predictions of island biogeography in the case of continental islands, where island formation typically splits continuous populations and thus vicariance al

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Germ layer formation and primary axis development rely on Fibroblast growth factors (FGFs). In Xenopus, the secreted serine protease HtrA1 induces mesoderm and posterior trunk/tail structures by facilitating the spread of FGF signals. Here, we show that the serpin Protease nexin-1 (PN1) is transcriptionally activated by FGF signals, suppresses mesoderm and promotes head development in mRNA-injecte

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Birds have sophisticated colour vision mediated by four cone types that cover a wide visual spectrum including ultraviolet (UV) wavelengths. Many birds have modest UV sensitivity provided by violet-sensitive (VS) cones with sensitivity maxima between 400 and 425 nm. However, some birds have evolved higher UV sensitivity and a larger visual spectrum given by UV-sensitive (UVS) cones maximally sensi

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Bullous pemphigoid (BP) and epidermolysis bullosa acquisita are subepidermal autoimmune blistering diseases mediated by autoantibodies against type XVII collagen (Col17) and Col7, respectively. For blister formation, Fc-mediated events, such as infiltration of inflammatory cells in the skin, complement activation, and release of proteases at the dermal-epidermal junction, are essential. Although i

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Background: A growing number of individuals are diagnosed with hereditary cancer. Though increased levels of anxiety and depression have been demonstrated around the time of genetic counselling, most individuals handle life at increased risk well. Data have, however, been collected on individual basis, which led us to focus on family perspectives of hereditary cancer. Methods: Lynch syndrome repre

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MicroRNAs (miRNAs) have been implicated in regulating multiple processes during brain development in various species. However, the function of miRNAs in human brain development remains largely unexplored. Here, we provide a comprehensive analysis of miRNA expression of regionalized neural progenitor cells derived from human embryonic stem cells and human foetal brain. We found miR-92b-3p and miR-1

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Measurements of differential production cross-sections of a Z boson in association with b-jets in pp collisions at root s = 7 TeV are reported. The data analysed correspond to an integrated luminosity of 4.6 fb(-1) recorded with the ATLAS detector at the Large Hadron Collider. Particle-level cross-sections are determined for events with a Z boson decaying into an electron or muon pair, and contain