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Mixed Micelles of a PEO-PPO-PEO Triblock Copolymer (P123) and a Nonionic Surfactant (C12EO6) in Water. A Dynamic and Static Light Scattering Study

The present article reports on static and dynamic light scattering (SLS and DLS) studies of aqueous solutions of the nonionic surfactant C12EO6 and the poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) triblock copolymer EO20PO68EO20 (P123) at temperatures between 25 and 45 degrees C. In water, P123 self-assembles into spherical micelles with a hydrodynamic radius of 10 nm, and at 40

Distinct Effects of Ligand-Induced PDGFR alpha and PDGFR beta Signaling in the Human Rhabdomyosarcoma Tumor Cell and Stroma Cell Compartments

Platelet-derived growth factor receptors (PDGFR) alpha and beta have been suggested as potential targets for treatment of rhabdomyosarcoma, the most common soft tissue sarcoma in children. This study identifies biologic activities linked to PDGF signaling in rhabdomyosarcoma models and human sample collections. Analysis of gene expression profiles of 101 primary human rhabdomyosarcomas revealed el

Considering rigor and relevance when evaluating test driven development: A systematic review

Context: Test driven development (TDD) has been extensively researched and compared to traditional approaches (test last development, TLD). Existing literature reviews show varying results for TDD. Objective: This study investigates how the conclusions of existing literature reviews change when taking two study quality dimension into account, namely rigor and relevance. Method: In this study a sys

Control and Communication with Signal-to-Noise Ratio Constraints

Popular Abstract in Swedish Reglering och kommunikation med störande brus Hur kan man på bästa möjliga sätt skicka data, till exempel en ljudsignal, när kommunikationen störs av brus och ändå måste ske snabbt? Och hur kan man på bästa sätt styra en process när styrsystemet begränsas av dålig kommunikation? Dessa frågor har undersökts i avhandlingen Control and Communication with Signalto-Noise This thesis is about two problems in the intersection of communication and control theory. Their common feature is that they involve communication over an additive white noise channel with a signal-to-noise ratio (SNR) constraint. The first problem concerns the transmission of a real-valued signal from a partially observed Markov source. The distortion criterion is the mean squared error and the

Woody biomass-based transportation fuels – A comparative techno-economic study

Production of synthetic vehicle fuels from biomass is a hot topic. There are several alternative fuels to consider when evaluating properties such as cost of production and energy efficiency to both product and final use in a road vehicle. Thermochemical conversion via gasification and downstream synthesis of fuels as well as biochemical conversion of woody biomass to ethanol is considered in this

Three-dimensional ultrasound assessment of the cervix for predicting time to spontaneous onset of labor and time to delivery in prolonged pregnancy

Objectives To determine whether three-dimensional (3D) ultrasound including power Doppler examination of the cervix is useful for predicting time to spontaneous onset of labor or time to delivery in prolonged pregnancy. Methods A prospective study was conducted in 60 women who went into spontaneous labor. All underwent transvaginal 3D power Doppler ultrasound examination of the cervix immediately

Supermacroporous cryogel matrix for integrated protein isolation - Immobilized metal affinity chromatographic purification of urokinase from cell culture broth of a human kidney cell line

A new type of supermacroporous, monolithic, cryogel affinity adsorbent was developed, allowing the specific capture of urokinase from conditioned media of human fibrosarcoma cell line HT1080. The affinity adsorbent was designed with the objective of using it as a capture column in an integrated perfusion/protein separation bioreactor setup. A comparative study between the utility of this novel cry

Upscaling of methane exchange in a boreal forest using soil chamber measurements and high-resolution LiDAR elevation data

Forest soils are generally considered to be net sinks of methane (CH4), but CH4 fluxes vary spatially depending on soil conditions. Measuring CH4 exchange with chambers, which are commonly used for this purpose, might not result in representative fluxes at site scale. Appropriate methods for upscaling CH4 fluxes from point measurements to site scale are therefore needed. At the boreal forest resea

Better Prognosis of Patients with Glioma Expressing FGF2-Dependent PDGFRA Irrespective of Morphological Diagnosis.

Signaling of platelet derived growth factor receptor alpha (PDGFRA) is critically involved in the development of gliomas. However, the clinical relevance of PDGFRA expression in glioma subtypes and the mechanisms of PDGFRA expression in gliomas have been controversial. Under the supervision of morphological diagnosis, analysis of the GSE16011 and the Repository of Molecular Brain Neoplasia Data (R

Immune function in a free-living bird varies over the annual cycle, but seasonal patterns differ between years

A central hypothesis of eco-immunology proposes trade-offs between immune defences and competing physiological and behavioural processes, leading to immunological variation within and among annual-cycle stages, as has been revealed for some species. However, few studies have simultaneously investigated patterns of multiple immune indices over the entire annual cycle in free-living birds, and none

Nocturia and Quality of Life: Results from the Boston Area Community Health Survey

Background: Nocturia, a common complaint in aging men and women, is frequently cited as the cause of nocturnal awakenings leading to sleep loss, daytime fatigue, and reduced quality of life (QOL). Objective: Investigate the association of nocturia with QOL and depressive symptoms among men and women. Design, setting, and participants: A population-based epidemiologic survey of urologic symptoms am

Energy Efficiency in the Residential Sector in the Ukraine: Achieving the Potential

Ensuring energy security, eradicating energy poverty, and reducing GHG emissions from the energy sector are some of the key reasons why energy efficiency will be addressed in the Ukraine. The residential sector, being among the major energy consumers in the national economy, has a large energy saving potential. Multi-storey residential buildings currently require general refurbishment, and this fa

Statistical power considerations in genotype-based recall randomized controlled trials

Validation of gene × environment interaction results from epidemiological studies in randomized clinical trials (RCTs) is usually hampered by insufficient statistical power. Genotype-based recall (GBR) refers to the design of studies in which subgroups of the population are selected based on their genotypes. In this thesis we test if a GBR approach of recruiting two groups of participants with dis

Land cover change and its influence on soil erosion in the Mara region, Tanzania : using satellite remote sensing and the Revised Universal Soil Loss Equation (RUSLE) to map land degradation between 1986 and 2013

En stor del av Östafrikas landsbygdsbefolkning är självförsörjande jordbrukare som på grund av begränsade markytor och förändrade klimatförhållanden riskerar misslyckade skördar och ökad fattigdom. I takt med att befolkningen växer blir miljöproblem som avskogning, erosion och urlakade jordar, samt övergödning av vattendrag och sjöar alltmer påtagliga. Syftet med den här studien är att kartläggaSub-Saharan Africa suffers from land degradation, depletion of natural resources and rural poverty. In the Lake Victoria Basin, where large parts of the population are small scale farmers, people are facing such issues coupled with altered climatic conditions. The focus area of this study is the Mara region in northern Tanzania, situated on the eastern lakeshore. Mara has experienced a doubling of

Socialchefer inom socialvården på Åland - Varför söka sig till socialchefsarbetet och varför bli kvar eller sluta?

Author: Jonna Granberg Title: Social directors in social work at the Aaland Islands – why become a social director and why stay or leave? Supervisor: Karin Kullberg Assessor: Håkan Jönson The purpose of this article was to examine which factors that influence the choise to become a social director and which factors that influence the desire to stay or leave the profession. To obtain the purpose,

Pinion bearing preload fluctuation with temperature

Minskade friktionsförluster har blivit föremål för omfattande forskning och utveckling inom bilindustrin. Som ett led i detta har förspänning av pinjonglager i relation till driftstempertur studerats i ett examensarbete på uppdrag av BorgWarner TorqTransfer Systems. Resultatet är anmärkningsvärt och motiverar fortsatt konstruktionsarbete. Alla känner nog till att bilen är en riktig miljöbov men fThis report is the written result of a Master Thesis conducted at the Division of Machine Design at the Faculty of Engineering at Lund University. The project has been carried out in collaboration with BorgWarner TorqTransfer Systems (TTS) AB in Landskrona. The car industry is growing vastly and thereby the associated levels of CO2 emissions. Extensive and sharpened regulations are continuously b

Optimization of a search for doubly-charged Higgs bosons in same-sign di-muon final states at a center of mass energy of 8 TeV with the ATLAS detector.

Standardmodellen inom partikefysik är den modell som för nuvarande bäst beskriver universums minsta beståndsdelar, och de fundamentala krafterna som verkar mellan dessa. De fyra fundamentala krafterna är den elektromagnetiska, den starka, den svaga och gravitationen (som dessvärre inte kan beskrivas med hjälp av Standardmodellen). Dessa krafter kan ses som kraftförmedlarpartiklar som växelverkar mIn this thesis an optimization of a previously performed inclusive search for beyond Standard Model Physics in same-sign di-lepton final states is performed, but tuned for a doubly-charged Higgs boson decaying to same-sign di-muons. The doubly-charged Higgs boson is a proposed fundamental particle whose existence would provide evidence for theoretical extensions of the Standard Model (SM) of parti

Helicobacter pylori catalase (KatA) and KatA-associated protein (KapA) interaction

Catalase transport in Helicobacter pylori Helicobacter pylori is a bacterium that lives in the human stomach of 50% of the world’s population. Its presence in the stomach induces a strong immune response in all these cases and the body’s response to fight off the infection causes an irritation of the stomach that may be symptomatic or asymptomatic. A persistent infection may lead to ulcers or in

Let it Flood - Housing Against Flooding in Kävlinge

Global warming and climate change is getting a serious issue and a great environmental threat that affects many aspects of life and our ways of living on this planet. The negative effects of climate change are endangering our communities, health and economy. Global warming can be considered as a main reason for sea rising levels, extreme heat which is responsible for many forests’ fires, severe dr