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Translational control of the spliceosome under oncogenic stress

Splicing in cancer Proteins are functional molecules responsible for every biochemical process that sustain living organisms. However, how genetic information is expanded to generate amazing diversity of proteins during development and in cancer remains still mostly unresolved. The mechanism we have to account for this diversity is known as splicing. Information-containing RNA molecules, copies

Uniformiteten och landgillet - en rättshistorisk studie om försvenskningen av Skåne

Genom freden i Roskilde 1658 kunde Sverige tillskansa sig det tidigare danska Skåne. Fredsavtalet garanterade skåningarna rätten till, bland annat, dansk lag och tidigare danska privilegier. Statens arbete mot uniformitet i provinsen, genom att försvenska området, tog dock sakta men säkert vid, och 1683 var arbetet utfört och uniformiteten införd. Huvudsyftet med uppsatsen har varit att klargöra vIn 1658, the former Danish region of Scania was ceded to Sweden due to the Treaty of Roskilde. The treaty also guaranteed the Scanian population its right to maintain their Danish law and retain their former Danish privileges. Despite this, the state soon started to work towards uniformity between Scania and Sweden by a process known as Swedification, a process which was completed in 1683. The mai

Development of Wet Electrostatic Precipitator for Generation of Nanoparticle-Protein Solution

För att undersöka nanopartiklars toxicitet finns behov av att producera väldefinierade nanopartiklar dispergerade i en kolloid suspension. Men även för andra områden så som nanomedicin finns ett behov av denna typ av lösningar. För att dispergera partiklarna i vätska används ofta ytaktiva ämnen. När dessa ämnen tillsätts adderas de på ytan av partikeln och förändrar partiklarnas yta. Då forskning To examine nanoparticle toxicity there is a need to produce defined nanoparticles dispersed in a colloidal suspension. Such a solution could also be interesting for other fields such as nano-medicine. In order to disperse the particles in the liquid there are often surfactant added to the process that alternates the surface of the particles. As the research shows that the surface of a nanoparticle

Hysterins undantag - En rättslig studie av häxprocessernas tidiga skede

Denna uppsats har till syfte att utreda det rättsliga klimatet och se på vilka faktorer som påverkade rättstillämpningen under de svenska häxprocessernas tidiga skede. Den ska även se hur detta tillsammans med myndigheternas agerande påverkade processernas fortsatta spridning. För att uppnå detta inleds uppsatsen med att ge en överblick över samhället och den gällande rätten vid häxprocessernas This paper aims to investigate the legal environment during period of 1667-1672 and to see which factors influenced the application of law during the Swedish witch trials in their early stages. It will also investigate how these factors, along with the actions of the authorities, affected how the early witch trials spread over the country. To achieve this, the essay begins by giving an overview of

Paint without strain

Workers within the painting and decorating trade are exposed to stresses and strains to a considerable large extent. Statistics from 2012 indicate that one out of four Swedish male painters and decorators suffer from work-related disorders. The objective of this thesis was to thoroughly examine the stresses and strains that professional painters and decorators are exposed to throughout an average

Skyddet mot barn- och tvångsäktenskap i Sverige ur ett civilrättsligt perspektiv

Syftet med den här uppsatsen är att ur ett civilrättsligt perspektiv undersöka hur de svenska civilrättsliga reglerna skyddar någon som riskerar att utsättas för barn- och tvångsäktenskap, samt olika myndigheters agerande och förhållningssätt när de möter någon som befinner sig i riskzonen för påtvingade äktenskap. En stor del av de äktenskap som ingås mot någons vilja berör parter som bor i oliThe purpose of this paper is to examine from a civil law perspective how the Swedish legislation protect anyone at risk for child and forced marriages, as well as how various government agencies intervene and approach situations when they meet someone who is at risk of forced marriage. A large part of the marriage entered against someone's will affect parties who live in different countries.

Application of an energy sensitivity analysis when refurbishing buildings in Sweden

The European commission have set targets regarding the reduction of emission of greenhouse gases, the improvement of the energy efficiency and the use of renewable resources of energy respectively by 20 % by the year of 2020. Swedish targets are even more ambitious compared to the European Commission that aims to reduce the greenhouse gas emissions by 40 %, improve the energy efficiency by 20 % an

Att vara eller inte vara native

Examensarbetets titel: Att vara eller inte vara native - en kvantitativ studie om native advertising på Instagram, och dess inverkan på konsumentattityd och beteende. Seminariedatum: 2019-01-17 Kursnamn: FEKH29 - Examensarbete i Marknadsföring på kandidatnivå, 15 högskolepoäng Författare: Isabelle Edenborg, Anna Frick, Emma Truvé Handledare: Oskar Christensson Nyckelord: Persuasion Knowledge ModelTitle: To Be or Not To Be Native - a Quantitative Study of Native Advertising on Instagram, and Its Effect on Consumer Behavior and Attitude. Seminar date: 2019-01-17 Course name: FEKH29, Degree project in Marketing Undergraduate Level, 15 University Credits. Authors: Isabelle Edenborg, Anna Frick, Emma Truvé Advisor: Oskar Christensson Key Words: Persuasion Knowledge Model, Marketing, Native Adve

Förädling av hamnområde

Bakgrund: I flera havsnära kommuner finns attraktiv mark med vattennära och central lokalisering som utnyttjas ineffektivt. Hur kan man ta tillvara på denna mark och hur har tidigare exploateringar genomförts? Utgångspunkten för studien var att hitta en bättre användning för mark i hamnområden vilket födde exjobbsidén. Svårigheter i exploateringsprojekt inom hamnområden har tidigare varit förknippBackground: In several seaside municipalities, there are attractive pieces of land with central location, near the water, that are inefficiently used. How is the land utilized and how has previous exploitation projects been carried out? The starting point for the study was to find a better use for ground areas in harbours, which gave birth to the idea for this master thesis. Difficulties in earlie

Evolutionary history of Zygaenidae: first comprehensive higher-level phylogeny and the estimated timing of lineage divergence

The 83 million year old family tree of burnet moths To classify the living world around them, early on humans started naming plants and animals in order to distinguish food from non-food, predator from prey, etc. In 1800s a practice of a more formal way of classifying the living world was started, in which using Latin names made the classification universal. The unique appearances were used to di

Påverkanstaktiker - mer än enbart en fråga om resistens

Syfte: Arbetets syfte var att undersöka hur medarbetare upplever deras chefers ledarskap och användning av olika grupper av påverkanstaktiker. Vidare var vi intresserade om detta påverkades eller modulerades något av chefernas egen ålder eller kön. Vidare ville vi även få en fördjupad förståelse hur denna relation mellan medarbetare, chef och påverkanstaktik påverkar medarbetarnas egenupplevda motPurpose: The purpose of this study was to generate an understanding of how followers experience their boss’s leadership as well as their use of different groups of influence tactics. Furthermore, we were interested in researching if this was affected or modulated by either the boss’s gender or age. We further wanted to generate a deeper understanding how the relation between follower and boss and

Synthesis of sialic acid 4-C derivatives in development of new antibacterial drugs

Kolhydrater kan användas som en energikälla i kroppen, men de kan även användas för mycket mer än så. I alla organismer finns celler vars ytor är täckta av olika sockermolekyler vilka är avgörande för cellernas överlevnad samt kommunikation med andra celler. Ett exempel på ett sådant socker är sialinsyra; en syrlig kolhydrat med en nio kol lång kolkedja. Patogener, exempelvis en del bakterier, kanSialic acids are a large family of acidic sugars. One of the most abundant is N-acetylneuraminic acid. Sialic acids are found at the terminal position of glycan chains of all cell types. Their wide distribution makes them have a broad set of biological functions, for example cell to cell interaction and communication. Bacteria can utilize sialic acid for two purposes; 1) as a source of carbon, nit

Telomere Shortening After Induced Premature Senescence by Ionizing Radiation

Induced Cell Aging by Radiation Aging is a natural phenomenon that affects almost all living organisms and brings with it an array of disease. In humans, aging is in part due to shortening of one’s telomeres. Telomeres are sequences of DNA at the end of our chromosomes that do not code for any genetic information. Thus, they can serve as protection, non-coding DNA taking damage that would otherwi

Miljöns betydelse för musikelevers musikintresse - en studie av uppfattningar hos musikklasselever och deras föräldrar

Title: The impact of environment on music students' commitment to music - a study of attitudes among music students and their parents. The purpose of this essay is to illustrate the importance of environmental influence on childrens' musical interests and factors inspiring children to play instruments and sing. The parents' opinions, regarding the extent of the effect of the environmen

Geografiska informationssystem för studier av polyaromatiska kolväten (PAH) : undersökning av djupvariation i BO01-området, Västra hamnen, Malmö, samt utveckling av en matematisk formel för beräkning av PAH-koncentrationer från ett kontinuerligt utsläpp

At the end of August 1999, the local government council of Malmö city decided that the area known as Kvarteret Bilen would be made available for the European Housing Exhibition 2001 (Bo01-mässan). Kvarteret Bilen extends over approximately 80 hectars and includes the western parts of the Western Harbour area (Västra hamnen) of Malmö. Kvarteret Bilen as a whole, but especially the western sections

Systemic Lupus Erythematosus, with focus on vascular wall changes, cardiac risk-factor awareness and cardiovascular events

Popular Abstract in Swedish SAMMANFATTNING PÅ SVENSKA Systemisk Lupus Erytematosus (SLE) är en kronisk inflammatorisk system sjukdom. Sjukdomen yttrar sig med stor variation, både avseende vilka organ områden och med vilken intensitet olika organ kan bli engagerade. Genom åren har prognosen för sjukdomen i sig dramatiskt förbättrats, genom att alla typer av organ manifestationer kan behandlas. SeSystemic Lupus Erythematosus is an autoimmune disease with a wide range of disease manifestations with respect to severity and magnitude of organ involvement. An increased risk of cardiovascular disease (CVD) compared with the general population causes both morbidity and mortality in SLE patients. Consequently prevention, early detection and treatment of arteriosclerotic manifestations are of high

Motion in Language and Experience : Actual and Non-actual motion in Swedish, French and Thai

This thesis deals with motion in language and non-linguistic experience, distinguishing between actual motion (AM) and non-actual motion (NAM). AM is the experience of continuous change in an object’s position, expressed in sentences such as 'The man runs through the forest' and 'The woman is walking'. NAM refers to dynamic qualities involved in conceiving or perceiving static situations and is ex

Long-term organic farming fosters below and aboveground biota: Implications for soil quality, biological control and productivity

Organic farming may contribute substantially to future agricultural production worldwide by improving soil quality and pest control, thereby reducing environmental impacts of conventional farming. We investigated in a comprehensive way soil chemical, as well as below and aboveground biological parameters of two organic and two conventional wheat farming systems that primarily differed in fertiliza

Potential Fit to the Department Outweighs Professional Criteria in the Hiring Process in Academic Libraries

Objective – To identify key factors affecting the probability of obtaining an interview and being hired for an academic library position. Design – An online survey was distributed via the following electronic mail lists: ACRL, LITA, COLLIB, METRO, ACQNET, COLLDV, ULS, EQUILIBR, and ALF. The questionnaire was posted via StudentVoice, an assessment survey provider. Setting – Academic libraries in