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Background: Well-managed warfarin treatment with a high time in therapeutic range (TTR) corresponds to fewer bleedings or thromboembolic complications. Many small centres manage their warfarin dosing manually, with little or no knowledge of their treatment quality as measured by TTR. AuriculA is a Swedish National web-based anticoagulation dosing system. Our hypothesis was that the web based dosin
The resurgence in developed countries of the common bed bug, Cimex lectularius, has led to a search for new sustainable methods to monitor and control this human ectoparasite. Because of increased resistance to insecticides, traps baited with attractive cues are considered a promising method to be developed into efficient monitoring tools for bed bugs. Despite their potential as attractants, only
Standard techniques for computed tomography imaging are not directly applicable to a carbonate rock because of the geometric complexity of its pore space. In this study, we first characterized the pore structure in Majella limestone with 30 per cent porosity. Microtomography data acquired on this rock was partitioned into three distinct domains: macropores, solid grains, and an intermediate domain
Synaptic degeneration and accumulation of the neurotoxic amyloid β-peptide (Aβ) in the brain are hallmarks of Alzheimer disease. Aβ is produced by sequential cleavage of its precursor protein, APP, by the β-secretase BACE1 and γ-secretase. However, Aβ generation is precluded if APP is cleaved by the α-secretase ADAM10 instead of BACE1. We have previously shown that Aβ can be produced locally at th
The mushroom Coprinopsis cinerea is a classic experimental model for multicellular development in fungi because it grows on defined media, completes its life cycle in 2 weeks, produces some 10(8) synchronized meiocytes, and can be manipulated at all stages in development by mutation and transformation. The 37-megabase genome of C. cinerea was sequenced and assembled into 13 chromosomes. Meiotic re
The Triassic-Jurassic boundary (c. 200Ma) marks one of the five largest Phanerozoic mass extinction events and is characterized by a major turnover in biotas. A palynological study of sedimentary rock slabs bearing dinosaur footprints from Rhaeto-Hettangian strata of Skane, Sweden was carried out. The theropod dinosaur footprints (Kayentapus soltykovensis) derive from the southern part of the aban
The adhesion molecule laminin α2 chain interacts with the dystrophin-glycoprotein complex, contributes to normal muscle function, and protects skeletal muscles from damage. Complete loss of the laminin α2 chain in mice results in a severe muscular dystrophy phenotype and death at approximately 3 weeks of age. However, it is not clear if the remaining members of the dystrophin-glycoprotein complex
It has been suggested that time selection and precedence in arrival order are more important during spring than autumn migration. Migrating birds are expected to fly at faster airspeeds if they minimize duration rather than energy costs of migration, and they are furthermore expected to complete their journeys by final sprint flights if it is particularly important to arrive at the destination bef
The intestinal microbiota is important for tolerance induction through mucosal immunological responses. The composition of the gut microbiota of an infant is affected by environmental factors like diet, disease and antibiotic treatment. However, already in utero these environmental factors can affect the immunological development of the fetus and influence the future gut microbiota of the infant.
Organic farming is promoted as a sustainable alternative to conventional farming, with positive effects on the diversity of plants and selected animal taxa. Here, we used a literature survey to collect presence/absence data on the composition of farmland bird, ground beetle, spider as well as butterfly and moth communities from 28 independent studies to identify genera and (sub-)families that had
Context:Genome-wide association studies (GWASs) of differentiated thyroid cancer (DTC) have identified associations with polymorphisms at 2q35 (DIRC3), 8p12 (NRG1), 9q22.33 (FOXE1) and 14q13.2 (NKX2-1). However, most of the inherited genetic risk factors of DTC remain to be discovered.Objective:Our objective was to identify additional common DTC susceptibility loci.Design:We conducted a GWAS in a
The plant respiratory chain contains several pathways which bypass the energy-conserving electron transport complexes I, III, and IV. These energy-bypasses, including type II NAD(P)H dehydrogenases and the alternative oxidase (AOX), may have a role in redox-stabilisation and regulation, but current evidence is inconclusive. Using RNA interference, we generated Arabidopsis thaliana plants simultane
The purpose of this qualitative study was to research how people's experience of having a sibling with an autism spectrum disorder affected their upbringing. We held six semi-structured interviews where we examined three different aspects of the participants’ lives in regard to their upbringing and sibling. 1: Their relationship with their sibling. 2: Their role in the family. 3: What kind of
Detta examensarbete handlar om PLC-programmering av en pelletspanna till ett nytt fjärrvärmeverk som byggs i Landskronas stadsdel Örja i samarbete med Deterministic Control AB, för en slutkund Landskrona Energi AB. Material som P&I-schema, funktionsbeskrivning, I/O-lista levererades av ett annat företag, AKJ. All programmering görs i ett ABB 800xA-system. De viktiga begrepp som examensarbetet
This thesis aims to explore the possibility of using deep learning techniques to mine opinions on Twitter, with the objective to predict the political opinion distribution in Sweden. Different methods of gathering and annotating training data are evaluated to achieve accurate and reliable predictions. The models are quite successful at predicting test data, achieving F1-scores in the range of 70 %
Despite a global increase in gender equality, intimate partner violence (IPV) still plagues all nations. Moreover, IPV is still a heavily stereotyped crime where women are victims and men are perpetrators. Due to the gendered nature of IPV, information that either conforms or deviates from gender expectations can change the perceptions of perpetrators and victims of IPV. The present study investig
Syftet med studien var att närma oss hur psykodynamiskt inriktade terapeuter som arbetar med barn med traumatiska erfarenheter, upplever sin kliniska verklighet och att få en inblick i på vilket sätt psykodynamisk barnterapi kan göra skillnad för dessa barn. Studien är uppbyggd på en kvalitativ grund och utgår från tolkande fenomenologisk anlays, IPA, (Interpretative Phenomenological Analysis). DaThe aim of the study was to approach how psychodynamically oriented therapists who work with children with traumatic experiences, experience their clinical reality and to gain an insight into how psychodynamic child therapy can make a difference for these children. The study is based on a qualitative basis and is based on interpretive phenomenological analysis, IPA, (Interpretative Phenomenologica
Bakgrund: Personer med autism har annorlunda sensorisk bearbetning vilket påverkar vardagsaktiviteter i hemmet och samhället. Omfattande forskning om barn med autism speglar hur sensoriska problem påverkar skolaktiviteter och fritidsaktiviteter som bidrar till stress, sämre deltagande i sociala umgängen och arbetsuppgifter. Även om vuxna personer med autism har sensoriska svårigheter belyser forskBackground: People with autism have a different sensory processing which affects daily occupations at home and in society. Extensive research about children with autism reflects how sensory difficulties affect school and leisure activities which contribute to stress, poorer participation in social gatherings and tasks. Although adults with autism experience sensory difficulties, research rarely hi
Soil temperature fluctuations are typical at high latitudes in early spring or late autumn. Freeze-thaw cycles (FTCs) occur when the soil temperature fluctuates around 0°C, causing a change in the state of the soil solution. Due to climate change, FTCs are predicted to become more frequent and intense, especially in the Arctic, Antarctic, and cold temperate regions. In this study, two experiments
Det finns till dags dato inget entydigt svar på vad som ger ett bra utfall i psykoterapeutisk behandling, faktorer som anses gemensamma för alla sorters terapi, så kallade Common Factors (CF) eller den specifika terapimetoden. Definitionen av CF varierar och kan härledas till alla delar av terapi såsom patientfaktorer, förändringsprocess och terapeutfaktorer. Som en del av POSE-projektet undersöktUnderstanding what constitutes a positive outcome in psychotherapeutic treatment remains a challenge, whether attributed to Common Factors (CF) shared across therapies or specific therapeutic methods. The definition of CF varies and can be traced to all aspects of therapy, including patient and therapist factors and the process of change. This study, as part of the POSE-project, examined the psych
