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Agricultural intensification and associated loss of high-quality habitats are key drivers of insect pollinator declines. With the aim of decreasing the environmental impact of agriculture, the 2014 EU Common Agricultural Policy (CAP) defined a set of habitat and landscape features (Ecological Focus Areas: EFAs) farmers could select from as a requirement to receive basic farm payments. To inform th

Background: Prediction of neurological outcome in unconscious patients after cardiac arrest (CA) forms the basis for decisions on further level-of-care based on results from clinical neurological examinations, neuroimaging (CT or MRI), neurophysiology (EEG or SSEP) and blood biomarkers of brain injury. Methods must be highly specific to avoid misclassifying patients with possibilities of a good ou

Johannes Magnus (1488–1544) was the last Catholic archbishop of Uppsala to hold residence in Sweden. He was also a historian and wrote a work in Latin about Swedish history that was to gain an unparalleled importance. The work is entitled Historia de omnibus Gothorum Sueonumque regibus, the ‘History of all the Kings of the Goths and the Swedes’. It is arranged as a series of biographies of over 20

Periampullary adenocarcinoma, including pancreatic cancer, has a poor prognosis that has not improved in the last decades. Therefore, in order to find more effective treatment regimens, it is necessary to gain more insight into the biology and clinical behaviour of these tumours. This thesis entails a thorough histopathological characterization of retrospectively collected tumours from a consecuti

The overall aim of this thesis is to examine how walking as a transport mode is constructed in the planning realm, affected by the built environment and perceived by the individual. This aim is related to the following research questions: (1) How are pedestrians and walking understood, constructed and perceived in the planning context? (2) How does individual traits and the built environment affec

This thesis focuses on processing and electro-optical investigations of two- and three-terminal photodetectors based on large arrays of around three million n+-i-n+ InP nanowires with embedded InAsP quantum heterostructures for broadband detection. First, we investigated the optoelectronic behavior of two-terminal photodetectors under selective 980 nm excitation of the 20 axially embedded InAsP qu

The built environment is important to achieve a sustainable society. From a sustainability perspective, refurbishment can be preferable to building anew. A significant proportion of the built environment needs to be refurbished. Refurbishment projects also provide the opportunity to proactively upgrade the working environment for users during operation and use.Research concerning the working envir

Background: Chromosomal translocations t(11;22) (q24;q12) are characteristic of about 80-90% of Ewing's sarcoma family of tumors [bone and soft tissue Ewing's sarcoma and peripheral neuroectodermal tumors (PNET)]. They generate ews/fli1 rearrangements showing great diversity in breakpoint exon combination. In about 5% of Ewing's tumors, ews is fused to the erg gene at 21q22. The various chimeric p

Background: Pesticide exposure may affect young children's neurodevelopment, but only few cohort studies have addressed possible effects of non-organophosphate pesticides. Objective: We evaluated associations between prenatal current-use pesticide exposure and neurodevelopmental outcomes among 1-year-old children from the Infants’ Environmental Health (ISA) birth cohort. Methods: To determine pren

Background: To identify subjects with rupture-prone atherosclerotic plaques before thrombotic events occur is an unmet clinical need. Thus, this proof-of-concept study aims to determine which rupture-prone plaque features can be detected using clinically available photon-counting computed tomography (PCCT). Methods: In this retrospective study, advanced atherosclerotic plaques (ex vivo, paraffin-e

The success of social movements is highly dependent on their sustainability, as in their efforts to produce meaningful change, they inevitably encounter oppressive dominant forces. With the advent of the social media era, scholarly research on collective action has acquired an additional dimension, bringing the role of their communicative constitution to the forefront of discussions. However, a de

Background: Glomerular filtration rate (GFR) is a key indicator of kidney function, typically estimated using creatinine or cystatin C. When cystatin-C-based eGFR is markedly lower than creatinine-based eGFR, this discrepancy may reflect a selective impairment in the filtration of medium-sized molecules, referred to as Shrunken Pore Syndrome (SPS), or more broadly, Selective Glomerular Hypofiltrat

The ever increasing demand for faster and more energy-efficient electricalcomputation and communication presents severe challenges for the semiconductor industry and particularly for the metal-oxidesemiconductorfield-effect transistor (MOSFET), which is the workhorse of modern electronics. III-V materials exhibit higher carrier mobilities than the most commonly used MOSFET material Si so that the

The unsustainable human impact on ecology and ensuing climate change necessitates the reduction of greenhouse gas emissions. The largest contributing industrial sector is the chemical industry, due to its petrochemical dependency. For this reason, and for the finite nature of fossil fuels, the chemical industry is forced to shift to sustainable sources, such as biorefinery products. The biorefiner

AbstractEndocarditis, or heart valve infection, can be caused by a number of pathogens, many of which are Gram-positive bacteria. The diagnosis is based on imaging techniques such as echocardiography and on blood culture. The implementation of fast and accurate species identification methods, such as the matrix-assisted laser desorption/ionisation-time of flight mass spectrometry (MALDI-TOF MS) in

Visst vore det fint om vi kunde producera nödvändiga kemikalier mer effektivt, förse alla människor med de läkemedel de behöver till en lägre kostnad än vad som är möjligt idag, och förhindra översvämningar i stadsmiljö? Men vad har dessa tre ting gemensamt, egentligen? Jo, att man kan optimera de olika processer som ligger bakom alla tre! Processer finns i princip överallt i världen, komplexa som eComplex processes can be seen as a series of actions, changes, and/or events that are related in different temporospatial manners, and thus are potentially difficult to understand. Optimizing such a process is therefore not necessarily a simple feat, and doing it experimentally may become both time-consuming and expensive. Computer-aided optimization therefore lends itself as a viable alternative,

The purpose of this dissertation is to contribute to a better understanding of the relations between music technology and girls and transgender persons (aged 13–21) in music making. The research subject is leisure time music making in music technology learning environments, where issues of gender equality are emphasized. A further aim is to discuss the music technology learning environment from th

Coastal flooding and erosion are worldwide problems that are further aggravated by rising sea levels and increasing population densities in coastal areas. In many of those areas, sandy beaches and dunes protect thehinterland from waves and extreme water levels during storms, while providing natural and recreational values. Sandy coasts are dynamic systems. Thus, risk assessments and coastal manage

Doctoral education in medicine, engineering, technology and science (METS) is in many ways different from doctoral education in the humanities or social sciences. In the METS disciplines, typically, students and supervisors work and publish together within the supervisors’ research projects. The projects are usually financed by the supervisors’ research grants and their success, in terms of high q

Background: High reproducibility and low intra- and interobserver variability are important strengths of cardiac magnetic resonance (CMR). In clinical practice a significant learning curve may however be observed. Basic CMR courses offer an average of 1.4 h dedicated to lecturing and demonstrating left ventricular (LV) function analysis. The purpose of this study was to evaluate the effect of init