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Associations between per- and polyfluoroalkyl substances (PFAS) and diabetes in two population-based cohort studies from Sweden

Background: Per- and polyfluoroalkyl substances (PFAS) have been suggested to contribute to the development of metabolic diseases such as obesity, diabetes and non-alcoholic fatty liver disease (NAFLD). However, evidence from epidemiological studies remain divergent. The aim of the present study was to evaluate associations between PFAS exposure and prevalent diabetes in a cross-sectional analysis

Standardization of serum creatinine is essential for accurate use of unbiased estimated GFR equations : Evidence from three cohorts matched on renal function

Background: Differences in the performance of estimated glomerular filtration rate (eGFR) equations have been attributed to the mathematical form of the equations and to differences between patient demographics and measurement methods. We evaluated differences in serum creatinine (SCr) and eGFR in cohorts matched for age, sex, body mass index (BMI) and measured GFR (mGFR). Methods: White North Ame

Longitudinal changes in hippocampal texture from healthy aging to Alzheimer's disease

Early detection of Alzheimer's disease is essential to develop preventive treatment strategies. Detectible change in brain volume emerges relatively late in the pathogenic progression of disease, but microstructural changes caused by early neuropathology may cause subtle changes in the MR signal, quantifiable using texture analysis. Texture analysis quantifies spatial patterns in an image, such as

Dietary fatty acids and endometrial cancer risk within the European Prospective Investigation into Cancer and Nutrition

Background: Diet may impact important risk factors for endometrial cancer such as obesity and inflammation. However, evidence on the role of specific dietary factors is limited. We investigated associations between dietary fatty acids and endometrial cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC). Methods: This analysis includes 1,886 incident endometrial ca

Autumn fueling behavior in passerines in relation to migratory distance and daylength

Songbirds have evolved diverse strategies to cope with seasonality, including long-, medium-, and short-distance migration. There is some evidence that birds with a longer migration distance deposit fuel faster. However, most studies focus on long-distance migrants. Comparisons between species with different migration distances are necessary to broaden our understanding of fueling capacity in migr

Temperature and age effects on latitudinal growth dynamics of the commercially valuable gadoid Northeast Arctic saithe (Pollachius virens)

It is well known that marine fish dynamics relate with climate variability, and predicting future population developments have become increasingly urgent with on-going climate change. One approach in widespread populations is to study how individuals from different parts of the distribution area respond to climate, thereby testing for potential resilience in terms of local adaptions against enviro

Linking multiscale deformation to microstructure in cortical bone using in situ loading, digital image correlation and synchrotron X-ray scattering

The incidence of fragility fractures is expected to increase in the near future due to an aging population. Therefore, improved tools for fracture prediction are required to treat and prevent these injuries efficiently. For such tools to succeed, a better understanding of the deformation mechanisms in bone over different length scales is needed. In this study, an experimental setup including mecha

Organic management and cover crop species steer soil microbial community structure and functionality along with soil organic matter properties

It is well recognized that organic soil management stimulates bacterial biomass and activity and that including cover crops in the rotation increases soil organic matter (SOM). Yet, to date the relative impact of different cover crop species and organic vs. non-organic soil management on soil bacteria and fungi and on SOM quantity and quality remains to be tested. We used a long-term (10 years) fu

Validation of standardized creatinine and cystatin C GFR estimating equations in a large multicentre European cohort of children

Background: Most validations of paediatric glomerular filtration rate (GFR) estimating equations using standardized creatinine (CR) and cystatin C (CYS) assays have comprised relatively small cohorts, which makes accuracy across subgroups of GFR, age, body mass index (BMI) and gender uncertain. To overcome this, a large cohort of children referred for GFR determination has been established from se

Altered biventricular hemodynamic forces in patients with repaired tetralogy of Fallot and right ventricular volume overload because of pulmonary regurgitation

Intracardiac hemodynamic forces have been proposed to influence remodeling and be a marker of ventricular dysfunction. We aimed to quantify the hemodynamic forces in repaired tetralogy of Fallot (rToF) patients to further understand the pathophysiological mechanisms as this could be a potential marker for pulmonary valve replacement (PVR) in these patients. Patients with rToF and PR>20% (n=18) and

Ungdomars spel om pengar : Spelmarknaden, situationen och karriären

Popular Abstract in Swedish Spel om pengar har blivit ett utbrett fenomen i Sverige under 1990-talet, med spelbutiker, spelhörnor i varuhusen, spelmaskiner och spel med kort och på roulette på pubar, pizzerior och restauranger, samt spel på Bingo-Lotto hemma i vardagsrummet. Förutom den ökade tillgången till legala spelformer blir det allt vanligare med spel i miljöer och sammanhang där det inte fGambling has become widely accepted in Sweden during the 1990s, with betting shops, gambling machines and casino-like gambling in pubs and restaurants, as well as Bingo-Lotto in our living rooms. Beyond the expansion in availability of legal gambling opportunities, the most notable change is the shift from gambling in specific venues to gambling in a much wider range of social settings. The conseq

Chemical signaling and insect attraction is a conserved trait in yeasts

Yeast volatiles attract insects, which apparently is of mutual benefit, for both yeasts and insects. However, it is unknown whether biosynthesis of metabolites that attract insects is a basic and general trait, or if it is specific for yeasts that live in close association with insects. Our goal was to study chemical insect attractants produced by yeasts that span more than 250 million years of ev

Hemodynamic forces using four-dimensional flow MRI : An independent biomarker of cardiac function in heart failure with left ventricular dyssynchrony?

Patients with heart failure with left ventricular (LV) dyssynchrony often do not respond to cardiac resynchronization therapy (CRT), indicating that the pathophysiology is insufficiently understood. Intracardiac hemodynamic forces computed from four-dimensional (4-D) flow MRI have been proposed as a new measure of cardiac function. We therefore aimed to investigate how hemodynamic forces are alter

Non-Visual Haptic Interaction Design - Guidelines and Applications

This dissertation has three cornerstones: * Haptics * Human-Computer Interaction (HCI) * Blind Users Haptics deals with controlling human movements and getting feedback through the sense of touch. A haptic interface transmits forces to a person’s hand or fingers in a way that mimics the sensation of touching real objects. Virtual haptic touch can be particularly useful for people with visual i

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https://www.saco.se/globalassets/lokala-akademikerforeningar/statlig/slu/nyhetsbrev/nyhetsbrev_2019-1.pdf - 2026-05-03

Meningserbjudanden och val: En studie om musicerande i musikundervisning på högstadiet

The purpose of this study is to elucidate affordances and meaning-making processes where students in Compulsory lower secondary education learn to play music together in music class. The data consists of a series of observed music lessons, performances and stimulated recall interviews in two 8th form classes, video recorded in the course of one term. The analysis focuses on students’ and their tea

Film Formation from Dispersions - Preparation and Mechanisms

Improved environmental consciousness and harsh legislation concerning volatile organic compounds (VOCs) during the 1980s led to an increase in the development in the field of polymer colloids. Solvent born coatings were replaced by polymer dispersions in aqueous solution, so called latex dispersions. As a consequence, numerous research programs concerning polymerization processes (e.g. emulsion po

Techno-economic evaluation of integrated lignocellulosic ethanol production

Popular Abstract in Swedish Syftet med studierna som presenteras i denna avhandling har varit att undersöka om fordonsetanol kan framställas på ett lönsamt och energieffektivt sätt från restprodukter från jord- och skogsbruk enligt svenska förhållanden. Mycket av den forskning som rör andra-generationens etanolproduktion går ut på att förfina och förbättra de separata delstegen i framställningsproSweden has claimed that it wants to have a fossil-free vehicle fleet in 2030 as a milestone of its ambitious goal for 2050 to be a country with a sustainable and resource-efficient energy supply without any net GHG emissions. Production of bioethanol from plant materials is one potential method of meeting this goal. A large amount of research has been devoted toward the development of sustainable

Cyclic nucleotide signalling systems in vascular smooth muscle cells and immune system cells with special reference to phosphodiesterases PDE3 and PDE4

Popular Abstract in Swedish Bakgrund: Signalsystem Alla flercelliga organismer är beroende av informationsöverföring mellan celler. Det behövs signaler från andra celler för att reglera tillväxt, ämnesomsättning m. fl. funktioner i olika vävnader. Oftast överförs signalerna via kemiska ämnen som antingen verkar i hela kroppen (hormoner) eller lokalt. När dessa ämnen når målcellen, binds de till eThe cyclic nucleotide signalling systems are important in vascular smooth muscle and in the immune system, and are of interest from a pharmacological point of view. Drugs which interfere with the cyclic nucleotide levels have profound effects on heart, blood vessels and airways and have actual or potential use in several important diseases, such as heart failure, hypertension, arteriosclerosis, as

Occupational exposure to particles and mitochondrial DNA : Relevance for blood pressure

Background: Particle exposure is a risk factor for cardiovascular diseases. Mitochondrial DNA (mtDNA) is a primary target for oxidative stress generated by particle exposure. We aimed to elucidate the effects of occupational exposure to particle-containing welding fumes on different biomarkers of mtDNA function, and in turn, explore if they modify the association between particle exposure and card