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Measurements of methane (CH4) molecules containing two rare isotopes (13CH3D and 12CH2D2), also termed doubly substituted or "clumped" isotopologues, have the potential to provide two additional isotopic dimensions to help investigate the mechanisms underlying global atmospheric trends in CH4. In this work, we summarise the current state of research on doubly substituted CH4 isotopologues, with an
BACKGROUND/AIM: Appendiceal adenocarcinomas are rare tumours with aggressive traits, most often diagnosed incidentally after routine appendectomy. Survival rates vary greatly between the different subgroups, and adenocarcinoma has the worst prognosis. Surgery is the only curative treatment, however, the long-term benefit of extended surgical resections over appendectomy has not been established. T
Introduction: Strategies for tuberculosis (TB) elimination in low-incidence countries involve screening recent migrants from TB-endemic regions for TB infection (TBI) and providing TB preventive treatment (TPT) to individuals with an increased risk of reactivation. This study aimed to determine TB incidence and identify reactivation risk markers in a cohort of asylum seekers in Sweden after screen
Background: Right ventricular dysfunction (RVD) is a marker of adverse outcomes in heart failure (HF). We used a 5-point RVD score to describe three phenotypes (preserved RV function, RVD and RV failure) and investigated their relationhip with cardiac function and their contribution to risk stratification. Methods: Patients (n = 201) with HF, undergoing right heart catheterization and echocardiogr
BACKGROUND: In health economics, health is regarded as part of an individual's human capital. As such it depreciates over time, and investments in health are made in order to keep the stock of health capital at the desired level. Using this framework for analysis of health-related behaviour and Swedish panel data, we examined whether the presence of asthma or allergy affects perceived health and i
To determine the impact of a family history of the common form of type 2 diabetes and the phenotype of the proband on anthropometric and metabolic variables in normoglycemic first degree relatives, we studied 2100 first degree relatives of patients with the common form of type 2 diabetes (FH+) and 388 subjects without a family history of diabetes (FH-). All subjects participated in an oral glucose
Protein HC, an extremely charge-heterogeneous lipocalin, carries a yellow-brown fluorescent chromophore of unknown structure covalently bound at an unidentified site of its polypeptide chain. Two chromophore-carrying peptides with 60% of the chromophore material (defined as material absorbing light at 330 nm) were isolated from pepsin-digested native human protein HC by reversed-phase high perform
A focused MeV proton beam at the Lund Ion Beam Analysis Facility has been used to induce radiation damage in transmission semiconductor detectors. The damage alters the response of detectors and degrades their charge transport properties. In this work, the radiation tolerance of ultra-thin silicon PIN detectors was studied as a function of proton fluences and detector thickness using a scanning pr
Background: Despite a decreasing incidence of peptic ulcer disease, most previous studies report a stabile incidence of ulcer complications. We wanted to investigate the incidence of peptic ulcer complications in Sweden before and after the introduction of the proton pump inhibitors (PPI) in 1988 and compare these data to the sales of non-steroid anti-inflammatory drugs ( NSAID) and acetylsalicyli
The best method to evaluate the seismic site response is by means of borehole vertical arrays that use earthquake records from different depths. In this paper we introduce the implementation of a single borehole sensor system (synchronized to a sensor on the surface) that is fixed at variable depths within a single well. This system is used for recording small amplitude earthquake signals at varia
Aggregation of the amyloid β-protein (Aβ) is believed to be involved in Alzheimer's disease pathogenesis. Here we have investigated the importance of the aromatic rings at positions 19 and 20 for the aggregation rate and mechanism by substituting phenylalanine with leucine. Aggregation kinetics were monitored as a function of time and peptide concentration by thioflavin T (ThT) fluorescence, the a
BACKGROUND: Understanding the dispersal and genetic structure of invasive insects across islands is important for designing management plans that are appropriate at spatial and temporal scales. For invasive parasites, population dynamics are largely determined by the distribution and density of their host species. The introduced parasitic fly, Philornis downsi, parasitises nestlings of endemic bir
This paper is the state of the art of charcoal signal studies (macro-, meso- and micro-charcoal) that have been carried out at the Epigravettian settlement of Mezhyrich. This work took part of the French ANR project "Mammouths". Charcoal signals have been found in both natural and archaeological (pits and activity areas) deposits that have been sampled during the 2007-2008 archaeological excavatio
The concept of ecosystem-based adaptation is advocated at international, national, and regional levels. The concept is thought to foster sustainability transitions and is receiving increasing interest from academic and governmental bodies alike. However, there is little theory regarding the pathways for its systematic implementation. It furthermore remains unclear to what degree the concept is alr
Feather mosses utilize various sources of nitrogen (N): they absorb N deposited on leaf tissue, they host N-2 fixing cyanobacteria, and they are able to take up N directly from soil. In addition to their importance as primary producers in boreal ecosystems, feather mosses play a significant role in N cycling. However, estimates of their ability to take up N from soil in situ are scarce. Further, c
A bioanode with high current density and coulombic efficiency was developed by co-immobilization of pyranose dehydrogenase from Agaricus meleagris (AmPDH) with the dehydrogenase domain of cellobiose dehydrogenase from Corynascus thermophiles (recDHCtCDH) expressed recombinantly in Escherichia coli. The two enzymes were entrapped in Os-complex modified electrodeposition polymers (Os-EDPs) with spec
Objective The objective of this study was to investigate whether a Medication Report also can reduce the number of patients with clinical outcomes due to medication errors. Method A prospective intervention study with retrospective controls on patients at three departments at Lund University Hospital, Sweden that where transferred to primary care. The intervention group, where patients received a
Context: The European Association of Urology presents its guidelines for vasectomy. Vasectomy is highly effective, but problems can arise that are related to insufficient preoperative patient information, the surgical procedure, and postoperative follow-up. Objective: These guidelines aim to provide information and recommendations for physicians who perform vasectomies and to promote the provision
