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PURPOSE: To estimate cause-specific mortality in osteoarthritis patients compared to the general population.METHODS: We identified all residents in southern Sweden aged 45-84 years in 2003. Through the Skåne Healthcare Register we identified those diagnosed with osteoarthritis in peripheral joints between 1998-2003. We followed all residents from 2004 until relocation outside of the region, death,
Directed relation graph with error propagation (DRGEP) method combined with extensive validation for 0D, 1D and 2D CFD modeling supported by sensitivity and Rate-Of-Production (ROP) analyses are implemented for comparative study of detailed and reduced kinetic mechanisms for CH 4
Approximately 20% of the population experience long-term pain. Women are generally more affected than men. Currently, pain researchers advocate a biopsychosocial perspective, which emphasises the importance of addressing psychological and social factors as well as biomedical ones in clinical practice. However, previous research shows that this holistic perspective is not always materialized in med
The importance of daylight to occupants’ health and wellbeing has been extensively documented, as well as its role in reducing electric lighting use. As a result, most countries have today some form of regulatory framework, specifying minimum daylight requirements for built spaces. The present Swedish building code (BBR – BFS 2011:6) includes general recommendations for daylight provision of resid
Currently there are no clinically recognized molecular biomarkers for malignant melanoma (MM) for either diagnosing disease stage or measuring response to therapy. The aim of this feasibility study was to develop targeted selected reaction monitoring (SRM) assays for identifying candidate protein biomarkers in metastatic melanoma tissue lysate. In a pilot study applying the SRM assay, the tissue e
Modeling Parkinson's disease remains a major challenge for preclinical researchers, as existing models fail to reliably recapitulate all of the classic features of the disease, namely, the progressive emergence of a bradykinetic motor syndrome with underlying nigrostriatal alpha-synuclein protein accumulation and nigrostriatal neurodegeneration. One limitation of the existing models is that they a
Aims: To examine whether genetic variants that predispose individuals to type 2 diabetes (T2D) could predict the development of diabetes after gestational diabetes mellitus (GDM). Methods: 13 SNPs (FTO rs8050136, CDKAL1 rs7754840 and rs7756992, CDKN2A/2B rs10811661, HHEX rs1111875, IGF2BP2 rs1470579 and rs4402960, SLC30A8 rs13266634, TCF7L2 rs7903146, PPARG rs1801282, GCK rs1799884, HNF1A rs116928
Climate change and the sustainability challenges of the 21st century require the reduction of greenhouse gas emissions in all sectors. Accordingly, political objectives urge for a shift from road to rail in logistics. This drives innovation, increased efficiency, and customer friendliness in the rail industry. These advancements are strongly needed as investments have been neglected in the past an
The aim of the project was to develop a methodology for the chromatographic analysis able to identify the key odorants in meaty food products. The approach was based on the analysis of an already in market product and the theoretical background of the meaty flavors sensorially. Firstly, a custom-made flavor was created for the experiments covering as much as possible a broad area of compounds prec
General syllabus for third-cycle studies in Media and Communication Studies Page 1 of 9 Faculty Board GENERAL SYLLABUS FOR MEDIA AND COMMUNCATION STUDIES Reg. No. U 2023/36 2023-02-02 General syllabus for third-cycle studies in Media and Communication Studies The general syllabus for third-cycle studies in media and communication studies was approved by the board of the Faculty of Social Sciences,
https://www.iko.lu.se/en/sites/iko.lu.se.en/files/2025-04/asp-media-and-communication-studies-20230202.pdf - 2026-07-10
The significance of load modeling for voltage stability studies has been emphasized by several disturbances, which have taken place in the past years. They have shown that the loads in combination with other dynamics are among the main contributors of prolonged low voltage conditions, voltage instability and collapse in the power system. As a result of these disturbances new investigations have co
Popular Abstract in Swedish POPULÄRVETENSKAPLIG SAMMANFATTNING (Svenska) I en klassisk monografi från 1855 med titel ”On the Constitutional and Local Effects of Disease of the Suprarenal Capsules” beskrev T. Addison det tillstånd som numera bär på hans namn. De 11 beskrivna patienterna innefattade alla huvudorsker till primär binjurebarkssvikt: autoimmunitet- rubbning i kroppens immunförsvar med pPolyglandular Autoimmune (PGA) syndrome type II in idiopathic Addison's disease: In a retrospective study of idiopathic Ad-dison's disease (median age at diagnosis 32.5 years, range 8-62; median observation time 17 years, range 0.5-41), 50% met the criteria for PGA syndrome type II. In PGA syndrome type II, 73% had ATD and 41% had IDDM. The full triad was present in 14%. The sequence of appearance
The human genome, in common with all mammalian genomes, carries a high load of inheritable retroviral sequences. We have identified and characterized a novel family of these endogenous retroviruses and have named this family HERV-F as based on the primer binding sites of three members. The HERV-Fs are C-type endogenous retroviruses that have unique gag, pol and env regions that are, based on phylo
Popular Abstract in Swedish De positiva hälsoeffekterna av ett högt intag av frukt och grönsaker har diskuterats intensivt under de senaste årtiondena. Flera befolkningsundersökningar har visat på samband mellan ett ökat intag av av frukt och grönsaker och en minskad risk för flera kroniska sjukdomar. Antioxidanter i vegetabilier anses vara en stor bidragande orsak till detta samband tack vare derThe health-promoting effects of fruits and vegetables have been extensively discussed during the past decade since epidemiologic studies have shown relations between increased intake of fruit and vegetables and decreased incidences of several chronic diseases. It has been suggested that antioxidants are a main contributors to the observed effects, for example by acting as scavengers of free radica
Popular Abstract in Swedish Populärvetenskaplig svensk sammanfattning Symptom från mag- och tarmkanalen som smärtor , diarrè, illamåande och blödningar är vanliga hos personer som missbrukar alkohol. Orsaken till denna typ av besvär är emellertid något oklart. Alkohol tas upp i blodet från magsäcken och övre delen av tunntarmen. Således kan alkohol ha effekter på slemhinnan i mag- och tarmkanalen.Background: Gastrointestinal symptoms such as dyspepsia, diarrhoea, and nausea are often seen in alcoholics. The causes are not clear. The stomach and upper small intestine are exposed to high alcohol concentrations. Yet, the majority of alcohol abusers do not exhibit macroscopic abnormalities at upper gastrointestinal endoscopy, although histological and electron microscopic (SEM) changes have be
Sustainable development is one of the greatest global challenges facing human beings in the 21st century. In order to tackle sustainability related problems, several global, European, and national targets for 2050 have been set. The transition of supply chains activities towards sustainability targets calls for designing new strategies and continuously identifying and tackling the challenges that
The overall aim of this thesis is to elaborate on the art of living with a traumatic spinal cord injury (SCI) in its relation to resources and norms in Swedish society. The thesis originates in part from a prevalence group of SCI individuals and is based on four studies. One is longitudinal and register based, and one is interview based. A paper on “ethics in the making” elaborates how general ver
The beach topography change in the nearshore zone may be induced by natural phenomena such as wind, wave, storm, tsunami, and sea level rise. However, it can also be caused by man-made structures and activities, for example, groins, detached breakwaters, seawalls, dredging, and beach nourishment. Therefore, understanding the beach topography evolution in this zone is necessary and important for co
Popular Abstract in Swedish Katalytisk omvandling av enkla kolväten till mer användbara substanser m.h.a. homogena/lösliga komplex av övergångsmetaller är ett mycket viktigt ämnesområde inom metallorganisk kemi. För att förstå hur processen går till har ett stort antal modellföreningar syntetiserats genom åren där man har studerat hur kol-väte eller kol-kol bindningar kan brytas. Man bör notera atThe work presented in this thesis deals with metallacyclic late transition metal complexes, obtained by intramolecular Csp3-H activation, and the application of such compounds in catalysis. The new hemilabile P,O phosphines N-methyl-N-propionyl-2-(diphenylphosphino)benzylamine (DPPAM), o-(diphenylphosphino)benzoic acid ethyl ester (DPPES), o-(diphenylphosphino)benzoic acid methyl ether (DPPET) and
Context: The insulin tolerance test ( ITT) is the current standard diagnostic test for the diagnosis of adult GH deficiency ( GHD), but alternative tests, such as the GHRH- arginine test, have been proposed. Objective: We investigated the sensitivity and specificity of the GHRH- arginine test using ITT as the gold standard in diagnosing GHD in a group of young adults treated with cranial irradiati
