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The effects of the pyrethroid insecticide cypermethrin on a natural freshwater community were studied in small in situ enclosures over an 11-day period. The experiment was conducted in a eutrophic lake using a regression design that included three untreated controls and a gradient of six unreplicated cypermethrin concentrations, ranging from 0.01 to 6.1 mug/l. This paper is the first in a series o

A series of CCK2 receptor ligands were analysed with respect to their interaction with binding sites in the membranes of COS-7 cells and SK-N-MC cells transiently expressing the human CCK2 receptor (short isoform). The ligands were YF476, YM022, AG041R, L-740,093, JB93182, PD134308, and PD136450. Their binding was analysed by radioligand competition using [H-3]L-365,260 as the labelled ligand. Sat

Background: High-risk alcohol consumption among university students is well documented. Several types of intervention have proved to be effective in reducing alcohol consumption. This study examines the 2-year outcome of 2 different alcohol intervention programs at university halls of residence. Methods: Ninety-eight university halls of residence (with 556 students) were cluster randomized to 2 d

Projekt Turnstone är ett samverkansprojekt delvis finansierat av Europeiska kommissionen. Projektet är ett initiativ av Stockholmspolisens gränsbevakningsenhet. Syftet med Projekt Turnstone är att minska gränsöverskridande brottslighet, förbättra dagligt samarbete mellan gräns, polis och kustbevakare i Östersjöregionen och förbättra säkerheten för passagerare i Östersjöregionen utan att göra avkalProject Turnstone is a collaborative project funded in part by the European Commission. The project is an initiative by the Stockholm Police. The purpose of the project is to improve day-to-day cooperation between border officers in the Baltic Sea region, decrease trans-boundary criminality, and increase security for passengers in the Baltic Sea area without compromising freedom of movement. Withi

This thesis concerns a highly efficient nanoparticle-based capillary electrochromatography separation technique and its coupling with mass spectrometric detection. From chromatographic theory, it is well known that the separation efficiency increases with decreasing particle size. However, as the particle size decreases, the pressure required to push a liquid through the column also increases. Thi

Popular Abstract in Swedish Livskvalitet, motivation och kostnader vid rehabilitering av patienter med långvariga muskuloskeletala besvär Långvariga muskuloskeletala besvär är ett omfattande medicinskt, socialt och ekonomiskt problem i utvecklade länder. Syftet med avhandlingen var att utvärdera ett multidisciplinärt rehabiliteringsprogram som fokuserade på Basal Kroppskännedom och kognitiv och Prolonged musculoskeletal disorders (PMSD) is an escalating medical, social and cost problem in developed countries. The complexity of PMSDs has emphasised the need of developing effective multidisciplinary rehabilitation programme with a holistic approach. The aim of the thesis was to evaluate the outcome of a multidisciplinary rehabilitation programme focusing on Body Awareness Therapy and cogn

Pressure overload activates cardiac fibroblasts leading to excessive production of extracellular matrix which may contribute to compromised heart function. The activated fibroblast acquires smooth muscle-like features such as expression of smooth muscle alpha-actin (SMA) and SM22 and is therefore referred to as myofibroblast. The molecular mechanisms underlying mechanical stress-induced myofibrobl

Background: Managed Ventricular Pacing (MVP) and Search AV+ (SAV+) are two pacing algorithms designed to reduce ventricular pacing, MVP promotes conduction by operating in AAI/R mode with backup ventricular pacing during atrioventricular block (AVB). SAV+ operates in DDD/R mode with a nominal AV extension of 290 ms during atrial sensing and 320 ms during atrial pacing. The reduction in ventricular

Background: The recommendations and the updated EAU guidelines consider early detection of PCa with the purpose of reducing PCa-related mortality and the development of advanced or metastatic disease. Objective: This paper presents the recommendations of the European Association of Urology (EAU) for early detection of prostate cancer (PCa) in men without evidence of PCa-related symptoms. Evidence

Objective: The 4.2-day half-life I-124 favors its use for positron emission tomography (PET) of monoclonal antibodies (mAbs). However, high positron energy and beta(+)-associated cascade gamma rays pose image resolution and background noise problems for I-124. This study evaluated quantitative PET of an I-124 mAb in tumor-bearing mice. Methods: An R4 microPET (TM) (Siemens/CTIMI, Knoxville, TN) wa

Adsorption of trimethyl phosphate (TMP) and triethyl phosphate (TEP) on well-characterized nanopartides of hematite (alpha-Fe2O3), maghemite (gamma-Fe2O3), and goethite (alpha-FeOOH) has been studied by in situ diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS), 2D correlation DRIFTS analysis, and X-ray photoelectron spectroscopy (XPS) on dry and water pre-covered surfaces. It is

According to the brood reduction hypothesis, parents adjust their brood size in response to current environmental conditions. When resources are abundant, parents can successfully raise all hatched offspring, but when resources are scarce, brood reduction, i.e., the sacrifice of some siblings to secure the quality of a subset of offspring, may maximize fitness. Differential transfer of maternal an

The 12-item Short-Form Health Survey (SF-12) is an abbreviated version of the SF-36, one of the most widely used patient-reported health outcome rating scales. Similar to the SF-36, it yields summary scores of physical and mental health (PCS and MCS, respectively). However, SF-36 derived PCS and MCS scores have not been found valid in neurological disorders such as Parkinson's disease (PD). Here w

The most common forms of familial thrombophilia are factor V Leiden (FVL) and prothrombin mutation (PTM). Homozygous FVL and PTM have long been feared conditions thought to cause high rates of morbidity and mortality. To analyse clinical features in patients with homozygous FVL and PTM, as well as patients with double heterozygosity for FVL and PTM. All patients with homozygous FVL, PTM or double

Modeling Parkinson's disease remains a major challenge for preclinical researchers, as existing models fail to reliably recapitulate all of the classic features of the disease, namely, the progressive emergence of a bradykinetic motor syndrome with underlying nigrostriatal alpha-synuclein protein accumulation and nigrostriatal neurodegeneration. One limitation of the existing models is that they a

An integrated study of palynology, Mossbauer spectroscopy, mineralogy and osmium isotopes has led to the detection of the first K-Pg boundary clay layer in a Southern Hemisphere terrestrial setting. The K-Pg boundary layer was independently identified at centimetre resolution by all the above mentioned methods at the marine K-Pg boundary site of mid-Waipara and the terrestrial site of Compressor C

Popular Abstract in Swedish Bakgrund: Det första elektrokardiogrammet (EKG) utfördes 1887 av Augustus Desiré Waller. Det innebar att spänningsskillnader mellan olika delar av hjärtat, under hjärtats arbete dvs. vid upprepade sammandragningar och avslappningar, kunde registreras med elektroder på kroppens yta. Metoden utvecklades vidare av Willem Einthoven, som fick nobelpriset för sitt arbete 1924Background and Methods: Signal-averaging ECG (SAECG), a bioelectrical processing method, is a further development of the conventional ECG. SAECG can detect voltage potentials in the microvolt range and provide a noise-reduced determination of QRS duration. Extended frequency spectra can be analysed. In adult patients after myocardial infarction it is used to predict the risk for arrhythmias and su

Ultra-fast substitution of chloride for bromide, iodide, azide and thiocyanate trans to ethene in Zeise's anion, [PtCl3(C2H4)](-), 1, has been investigated in methanol solvent by use of cryo temperature diode array stopped-flow spectrophotometry. Reactions follow the usual two-term rate law for square-planar substitutions, k(obs)=k(1)+k(2)[Y] (where k(1)=k(MeOH) [MeOH]), with k(1)=118+/-10 s(-1) a

Background and Purpose-The proportion of immigrants has increased in Sweden markedly during the last decades, as in many other Western countries. Incidence of stroke has increased during this period. However, it is primarily unknown whether incidence of stroke and stroke subtypes in Sweden is related to country of birth. Methods-Incidence of first-ever stroke was followed during 10 years in a coho

The aims of this thesis were to 1) compare different methods for detection of antibodies against thyroglobulin (TgAb) and thyroid peroxidase (TPOAb), particulary in children with chronic autoimmune thyroditis (AIT), 2) investigate if maternal enterovirus infection is a risk factor for development of AIT in offspring, 3) ascertain the prevalence of thyroid autoantibodies in cord blood sera from chi