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BACKGROUND AND OBJECTIVE: Although smoking is associated with an increased incidence of cardiovascular disease and death, many smokers remain healthy after many years of smoking. Our objective was to assess whether this variation is related to rate of decline of respiratory function. DESIGN: This was a population-based cohort study, its subjects being men born in 1914 from Malmo, Sweden. METHODS:

The structural basis for the biological specificity of human cystatin C has been investigated. Cystatin C and other inhibitors belonging to family 2 of the cystatin superfamily interact reversibly with target peptidases, seemingly by independent affinity contributions from a wedge-shaped binding region built from two loop-forming inhibitor segments and a binding region corresponding to the N-termi

An integrated IT technology, characterized by a change in information support from a strong specialization towards greater integration has been introduced within the surveying company in Sweden. The aim of this study is to compare and describe effects of the transition to this new information technology in relation to job and organizational characteristics and effectiveness and well-being measures

Lake and peat corings on three Azores islands in the central North Atlantic, resulted in the discovery of a 6000 year long lacustrine sequence in a small crater lake, Lake Caveiro, on the island of Pico. This island is dominated by Pico mountain (2351 m), Portugal's highest mountain, and the lake site is situated at 903 in asl. Two sediment profiles, one central and one littoral, were sampled. Due

Immotile-cilia syndrome is characterized by severe respiratory distress from early infancy, and also often by situs inversus. The first description of the disease was based on just four persons, but reasons were given to suggest that the disorder may not be exceedingly rare. The purpose of the present study was to estimate just how rare or how common it is and to evaluate its association with situ

The maximum concentration of water-insoluble solids (WIS) in simultaneous saccharification and fermentation (SSF) is restricted due to inhibition of the enzymes and the yeast, as well as mass transport problems caused by the viscosity of the pretreated material. However, the higher the concentration of WIS during SSF the less energy is needed in the subsequent distillation and evaporation steps. I

A quantitative reverse transcription-PCR (qRT-PCR) method was developed to monitor the relative expression of the type B botulinum neurotoxin (BoNT/B) gene (cntB) in Clostridium botulinum. The levels of cntB mRNA in five type B strains were accurately monitored by using primers specific for cntB and for the reference gene encoding the 16S rRNA. The patterns and relative expression of cntB were dif

Common disability scales in multiple sclerosis (MS) are often weighted towards physical disability. Non-motor symptoms such as depression, fatigue and pain substantially influence wellbeing in MS. Health-related quality of life (HRQoL) measures the broader impact of MS and might indicate less obvious disease burdens. We analysed HRQoL, using the Nottingham Health Profile Part I (NHP-I), among 345

Objectives: To compare a laparoscopic (totally extraperitoneal patch (TEP)) and an open technique (Lichtenstein) for inguinal hernia repair regarding recurrence rate and possible risk factors for recurrence. Summary Background Data: Laparoscopic hernia repair has been introduced as an alternative to open repair. Short-term follow-tip suggests benefits for those patients operated with a laparoscopi

With the exception of the GS-1/Younger Dryas cold period marine reservoir ages for the Last Deglaciation in the North Atlantic-Norwegian Sea are generally assumed to have been around 400-500 radiocarbon years in magnitude (Earth Planet. Sci. Lett. 126 (1994) 275; Radiocarbon 37 (1995) 53; Quat. Res. 52 (1999) 104; Nature 412 (2001) 724). By comparing the climate records obtained from the GRIP ice-

A novel minicolumn chromatgraphic method to monitor the production of inclusion bodies during fermentation and anenzyme-linked immunosorbent assay (ELISA) system allowing direct analysis of the particles with surface-displayed antigens are described. A 33-kDa protein containing 306 amino acids with three sulfur bridges produced its inclusion bodies wits labeled with polyclonal antibodies against 1

Background : Reduced taste and smell, chewing problems and swallowing dysfunction are common among elderly people and affect perception, food choice and the ability to eat. Objective : To study the preference for texture-modified carrot and meat products in elderly people aiming to meet the needs of people with impaired chewing and/or swallowing. Design : Data were collected using questionnaires

Insect damage is a general problem that disturbs the growth of forests, causing economic losses and affecting carbon sequestration. Coarse-resolution data from satellites are potentially useful for national and regional mapping of forest damage, but the accuracy of these methods has not been fully examined. In this study, a method was tested for the mapping of defoliation in Scots pine [Pinus silv

Phytase is an important enzyme in the food/feed industry. It catalyzes the hydrolysis of phytate, an anti-nutrient compound present in cereals and grains, to release orthophosphate and myo-inositol-6-phosphate with lower degrees of phosphorylation. Phytic acid is a strong chelator capable of complexing with a variety of metal ions under neutral and alkaline conditions, as well as with proteins and

Popular Abstract in Swedish Många av dagens biotekniska processer syftar till att framställa protein. Det är proteinets användningsområde som är avgörande för vilka renhetskrav som ställs på produkten. I vissa fall måste proteinet vara helt fritt från föroreningar för att inte åstadkomma oönskade effekter. Vaccinframställning är ett exempel på en sådan tillämpning. För andra ändamål, t ex vid framTwo polymers, alginate and Eudragit S-100 were used as reversibly soluble-insoluble ligand carriers for the selective isolation of enzymes and lectins respectively. These two polymers have the inherent property of being precipitated under well defined conditions. Alginate was made insoluble by the addition of Ca2+ ions, and Eudragit S-100 by a pH shift. The polymers were modified with affinity lig

When adapting environments for the physically disabled, it is important to encourage and activate not only the person concerned, but also other people involved or affected. A computer aided planning tool has been developed to support the participation of all persons involved, as well as supporting the planner’s (e.g. an occupational therapist) design of the environment. The prototype development a

In any research field the transformation of raw data into conclusions is a critical phase, necessitating a systematic approach. The basic question is: How can I as a (design) researcher corroborate my conclusions? This paper is based on a study of the analytical/interpretative portion of papers published in the Proceedings of the 2006 Design & Emotion Conference. We investigate how the authors

Popular Abstract in Swedish Migration (folkvandring) är idag en global företeelse. Orsaken till migrationen varierar och kan bero på krig och förföljelse, naturkatastrofer, familjeskäl, fattigdom, studier eller sökande efter arbete. I slutet av förra seklet var Sverige en nation där fattigdom och religiöst förtryck drev drygt en miljon människor över haven till Nordamerika och andra världsdelar. IAbstract Aims: To analyse the influence of migration status (country of birth/ethnicity), accultura-tion, socio-economic and psychosocial factors on self-reported psychiatric illness, suicide attempt, total mortality and violent death. Methods: Three main data sources were used: suicide attempts in the catchment area of Lund University Hospital (PASIS) during 1991–94; the Swedish Survey of Living