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Two groups of normal subjects were submitted to repeated automated static threshold perimetry. Perimetric results were strongly affected by the level of experience in some subjects; in the majority, however, the effect of experience was small. Initial field tests often showed high numbers of depressed points. Sensitivity increased with perimetric training, particularly between the first sessions.
OBJECTIVES: Overweight is associated with advanced stage at diagnosis in breast cancer patients. This could be explained by specific tumour characteristics or tumour promoting factors in the obese, but a diagnostic delay could also be of importance. Mammographic screening has caused a change towards diagnosis of less advanced tumours. This study investigates invitation to mammographic screening an
Summary The t(X;7)(q22;q34), a translocation not previously reported in a neoplastic disorder, was identified and molecularly characterised in a paediatric T-cell acute lymphoblastic leukaemia (T-ALL), subsequently shown also to harbour a deletion of 6q, a STIL/TAL1 fusion and an activating NOTCH1 mutation. The t(X;7) was further investigated using fluorescence in situ hybridisation (FISH), real-t
Background Medical adherence is important in the treatment of depression. Primary medical adherence, i.e. patients collecting their newly prescribed medications from pharmacies, is very different depending on the drug prescribed Objective To assess the rate of primary medical adherence in patients prescribed antidepressants and to identify characteristics that make patients less likely to pick up
Stem cell factor (SCF) binds the receptor tyrosine kinase c-Kit and is critical for normal hematopoiesis. Substitution of valine for aspartic acid 816 (D816V) constitutively actives human c-Kit, and this mutation is found in patients with mastocytosis, leukemia, and germ cell tumors. Immortalized murine progenitor cells (MIHCs) transduced with wild-type c-Kit proliferate in response to SCF, wherea
Popular Abstract in Swedish Vi lever i en tid och i ett samhälle där kemikalier har blivit en naturlig del av vår industrialiserade vardag. Till stor del ligger kemikalieindustrin bakom flera av de stora tekniska framsteg som gör att västvärlden har den levnadsstandard den idag har. Tyvärr har den stora spridningen av icke naturligt förekommande kemikalier ibland också negativa effekter både på miThe modern world is increasingly dependent of the use of chemicals. The chemical industries have greatly contributed to the high standard of living in industrialised societies, and chemical compounds surround us in everyday life. Unfortunately, a vast number of chemicals cause adverse effects on the environment and human health. One such concern is chemical hypersensitivity, which is a state cause
A project focusing on identifying and describing maritime risks is being conducted in the heavily trafficked water area of the Sound, situated in northern Europe between Sweden and Denmark. This paper reports of a test of a first version of a questionnaire constructed for measuring safety culture onboard vessels.48 crew members on a Swedish registered passenger/cargo ship completed and returned th
Single crystals of Cs2CuCl4 and Cs2CoCl4 have been investigated at high pressures by X-ray diffraction techniques, using a diamond anvil cell. Increasing the pressure to just below 40 kbar caused the crystallinity of Cs2CuCl4 to deteriorate rapidly. This was accompanied by a color change from yellow/orange at lower pressures to deep red, suggesting, e.g., a major change of the coordination geometr
This paper represents the first sketches of what will hopefully grow into a larger postdoctoral project, the subject of which will be the relationship between the world of the Hebrew Bible and that of the Indo-European cultures that was its early neighbours, particularly the Anatolian cultures of the Hittites, Luwians, etc. My goal is to examine how ideas, concepts and words from Indo-European sou
Atmospheric aerosol particles typically consist of inorganic salts and organic material. The inorganic compounds as well as their hygroscopic properties are well defined, but the effect of organic compounds on cloud droplet activation is still poorly characterized. The focus of the present study is the organic compounds that are surface active i.e. tend to concentrate on droplet surface and decrea
Test Case Prioritization and Selection (TCPS) methods aim to order or select tests to minimize test execution time without significantly reducing test coverage. In collaboration with a System Analysis Team at Arm, this project demonstrated machine learning-driven prioritization in an industrial Continuous Integration (CI) pipeline, using predictive models to optimize test execution. The team runs
Background: Dietary management of phenylketonuria (PKU) focuses on restricting phenylalanine (Phe) intake. The European PKU guidelines and the PKU Dietary Handbook recommend a simplified PKU diet, allowing unrestricted consumption of many low-Phe foods, called free foods. While this approach may reduce the treatment burden for patients, its implementation varies. This study investigated practi
AimsTo evaluate the association between diabetes and four peripheral nerve entrapment syndromes: carpal tunnel syndrome (CTS), ulnar nerve entrapment (UNE), radial nerve entrapment (RNE), and tarsal tunnel syndrome (TTS).MethodsThis retrospective cohort study used the Merative™ MarketScan® Commercial Database (2007–2023). Adults ≥18 years were classified as having diabetes or serving as controls.
Clonal hematopoiesis of indeterminate potential (CHIP) is characterized by age-related somatic mutations in hematopoietic stem and progenitor cells (HSC/Ps) and is correlated with an increased risk of myeloid malignancies, elevated inflammatory pathways in circulating myeloid cells, higher all-cause mortality, chronic kidney disease, and cardiovascular disease. The pathophysiology of inflammatory
Biological treatment of cyanide-contaminated wastewater is mediated by microbial consortia in which different organisms perform distinct, functionally specialized roles. This study investigated microbial communities involved in gold mine wastewater treatment with integrated aerobic-anoxic reactors seeded with consortia from an alkaline soda lake, Lake Chitu. Whole-genome sequencing of isolates (WG
Combustion of NH3 with H2 addition can improve the combustion stability. In this study, the laminar burning velocities (LBVs) of NH3/H2/O2/CO2 mixtures were determined under atmospheric pressure and an initial temperature of 303 K by the heat flux method, spanning CO2 fractions of 0.50-0.75, H2 fractions of 0.20-0.70, and equivalence ratios of 0.6-1.5. Evaluations of three kinetic models (modified
A study was conducted to investigate the new and frequently discussed concept curling parents. There were no previous studies of curling parenting, and therefore traditional classifications of parenting (Baumrind, 1967, 1980; Maccoby & Martin, 1983) have been used for comparison. Parents (N=140) born between 1959 and 1981 participated. They completed questionnaires to establish their level of
It is commonly understood that Intellectual Property Regimes are aimed at protecting private rights and in doing so sometimes neglect public interests. Historically IP systems were considered to allow authors or creators to secure certain monopolies on rights, hence in the 1970s and 1980s the concern over public needs came forward requiring the IP system to respond to it in a way that would stimul
Skatterättsligt företrädaransvar innebär att en företrädare för ett bolag blir solidariskt betalningsansvarig med bolaget för dess obetalda skatter. Regleringen kring företrädaransvar finns i 59 kap. 12–15 §§ skatteförfarandelagen, och stadgar att en företrädare för en juridisk person kan bli personligt betalningsansvarig för bolagets tillkortakommanden med skatteinbetalning. Företrädaransvaret blPersonal liability according to the law of tax proceedings (2011:1244) regulates that a representative of a corporation will be jointly and severally liable with a corporation for its unpaid taxes. The statute of the personal liability of a representative are found in chapter 59, paragraphs 12-15 in the Swedish tax law. According to these paragraphs, a representative of a corporation could be forc
OBJECTIVE: Chronic primary prostate pain syndrome (PPPS), usually referred to as chronic prostatitis with chronic pelvic pain syndrome (CP/CPPS), affects approximately 10% of all men. The National Institute of Health-Chronic Prostatitis Symptom Index (NIH-CPSI) was developed for clinical assessment and research evaluation of this patient category. The objective of this study was to translate the N
