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Der p 2 is one of the most important allergens from the house dust mite Dermatophagoides pteronyssinus Identification of human IgE Ab binding epitopes can be used for rational design of allergens with reduced IgE reactivity for therapy. Antigenic analysis of Der p 2 was performed by site-directed mutagenesis based on the x-ray crystal structure of the allergen in complex with a Fab from the murine

BACKGROUND: Diagnostic testing is essential for disease surveillance and test-trace-isolate efforts. We aimed to investigate if residential area sociodemographic characteristics and test accessibility were associated with Coronavirus Disease 2019 (COVID-19) testing rates.METHODS: We included 426 224 patient-initiated COVID-19 polymerase chain reaction tests from Uppsala County in Sweden from 24 Ju

Aim: To investigate the fees charged by Swedish dentists for root fillings, coronal restorations and further dental interventions during a follow-up period of 5–6 years. Methodology: A total of 248 299 root fillings were linked with the tooth, the patient and the provider and entered into the Swedish Social Insurance Agency register in 2009. The data register also recorded the subsidy-based (sched

Background Mental health interventions should demonstrate an effect on patients' functioning as well as his/her needs, in particular on unmet needs whose assessment depends on the perspective of either the patient or the clinician. However, individual met and unmet needs appear to change over time, qualitatively and quantitatively, raising questions about their sensitivity to change and about the

Background Increased postoperative cardiac troponin (cTn) independently predicts short-term mortality. Previous studies suggest that preoperative cTn also predicts major adverse cardiovascular events (MACE) and mortality after noncardiac surgery. The value of preoperative and perioperative changes in cTn as a prognostic tool for adverse outcomes has been sparsely investigated. Methods and findings

This paper is dedicated to a global correlation of marine Permian-Triassic boundary layers on the basis of partially published and original data on the δ13Corg and δ13Ccarb values of the Suol section (Setorym River, South Verkhoyansk region). The section consists of six carbon isotopic intervals, which are easily distinguishable in the carbon isotopic curves for a series of Permian-Triassic refere

Background Preeclampsia is considered a major cause of maternal and fetal morbidity and mortality. The aim of the present case-control study in Sweden was to assess the hypothesized association between low serum vitamin D concentrations in early pregnancy and the risk of developing preeclampsia since vitamin D may play a role in early placental development. Methods The study included 296 women dia

Sommaren 2014 deklarerade Abu Bakr Al-Baghdadi, ledare för den extrema jihadiströrelsen Islamiska staten (IS) att ett kalifat hade etablerats i Irak och Syrien, med antydan om global expansion som alla måste underordna sig. Därefter följde en skriftlig kalifatsdeklaration, författad av IS kommunikatör och talesman Abu Muhammad Al-Adnani. Denna uppsats undersöker om det är så att olika typer av ide

Conventional guidance on the design and management of urban roads and streets has tended to focus on either arterial roads or local access streets. There is currently a lack of a clear, consistent approach to the design of arterial streets, which combine both significant through traffic and urban place functions. This report aims to address this gap, by setting out an approach to the design and ma

This essay complements the monetary literature by estimation and simulation of a New-Keynesian macro model featuring financial market frictions and long bond portfolio policy. The model is an extended version of the canonical three-equation New-Keynesian model with segmented financial markets distinguishing the short-term money market from the long-term bond market. Our data is U.S. quarterly data

Three-dimensional food printing is an emerging application within the realm of 3D printing with the potential of transforming the foods we consume. The technique harbors incredible potential for improving the eating experience of people suffering from dysphagia, an ailment which causes discomfort at the time of swallowing. Patients suffering from this condition have special diets consisting of tex

Water is a crucial resource for our planet and a part of the accommodation sector´s environmental management. So far most attention has been paid to the direct water use such as for guest bathrooms, swimming pools and irrigated gardens. There is however also an indirect water use trough food and fuel consumption which has not been a focus for hotels environmental commitment but appears to stand fo

Water is a crucial resource for our planet and a part of the accommodation sector´s environmental management. So far most attention has been paid to the direct water use such as for guest bathrooms, swimming pools and irrigated gardens. There is however also an indirect water use trough food and fuel consumption which has not been a focus for hotels environmental commitment but appears to stand fo