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Background The prognosis in adults with congenital aortic valve disease is usually favourable; nevertheless, a number of medical and social factors might hamper long-term prognosis and quality of life. With a focus on physical exercise level, data from the Swedish National Registry on Congenital Heart Disease (SWEDCON) were analysed and variables associated with health-related quality of life in a
The tyrosine kinase inhibitor dasatinib exerts immunosuppressive effects on T-cells and NK-cells in vitro. However, in some dasatinib-treated leukemia patients, clonal lymphocytosis with large granular lymphocyte (LGL) morphology develops, and this is associated with enhanced therapeutic responses. To elucidate the mechanistic basis for this paradoxical observation, we conducted detailed phenotypi
OBJECTIVE: To compare how three different energy adjustment approaches influence the ranking of individuals on fat intake, and to examine the relation between fat intake and socio-economic, demographic and lifestyle characteristics for each energy adjustment approach. DESIGN: A cross-sectional analysis project, using a sub-sample (7055 women and 3240 men) from the Malmo Diet and Cancer Study. Diet
Background & Aims: Patatin-like phospholipase domain-containing protein 3 (PNPLA3) rs738409 polymorphism is associated with NAFLD severity and the PNPLA3 gene is expressed in the kidneys, but whether PNPLA3 rs738409 polymorphism is also associated with renal tubular injury (RTI) is uncertain. We assessed the effect of PNPLA3 genotypes on biomarkers of RTI and glomerular function in subjects wi
Doxorubicin (DOX) is a cornerstone drug in the treatment of osteosarcoma. However, achieving sufficient concentration in the tumor tissue after systemic administration with few side effects has been a challenge. Even with the most advanced nanotechnology approaches, less than 5% of the total administered drug gets delivered to the target site. Alternatives to increase the local concentration of DO
Background: Despite early referral of uraemic patients to nephrological care, suboptimal dialysis initiation (SDI) remains a common problem associated with increased morbimortality. We hypothesized that SDI is related to pre-dialysis care.Methods: In the 'Peridialysis' study, time and reasons for dialysis initiation (DI), clinical and biochemical data and centre characteristics were registered dur
Long term multiple systemic antibiotics form the cornerstone in the treatment of bone and joint tuberculosis, often combined with local surgical eradication. Implanted carriers for local drug delivery have recently been introduced to overcome some of the limitations associated with conventional treatment strategies. In this study, we used a calcium sulphate hemihydrate (CSH)/nanohydroxyapatite (nH
Background: High expression of the RNA-binding motif protein 3 (RBM3) has been shown to correlate, with prolonged survival in several malignant diseases and with the benefit of platinum-based chemotherapy in ovarian cancer. The aim of this study was to evaluate RBM3 in metastatic colorectal cancer (mCRC) as a prognostic factor for overall survival and in relation to benefit of first-line chemother
Background: It remains unclear whether heritable factors can contribute to risk stratification for ischemic stroke in patients with atrial fibrillation (AF). We examined whether having a sibling with ischemic stroke was associated with increased risk of ischemic stroke and mortality in patients with AF. Methods and Results: In this nationwide study of the Swedish population, patients with AF and t
Objective: Atherosclerosis is characterized by accumulation of lipids, cells and extracellular matrix (ECM) proteins in the arterial wall. Collagen type I (COL1), a component of the arterial ECM, is cleaved by matrix metalloproteinases (MMPs) and known to be remodelled in atherosclerosis. We explored whether the MMP-mediated COL1 biomarker, C1M, was associated with cardiovascular events, cardiovas
MVEN03_Planering_Schema_HT_2020_v2.xlsx MILJÖVETENSKAP Preliminär planering/schema 200517 Kurs: MVEN03 ‐ Miljövetenskap: Analys och metodik, 15 hp HT 2020 Kursansvarig: Nina Reistad NR nina.reistad@fysik.lth.se Lärare: Charlotta Turner CT charlotta.turner@chem.lu.se Christian Lindh CL christian.lindh@med.lu.se Per Erik Isberg PEI per‐erik.isberg@stat.lu.se Pål Axel Olsson PAO pal_axel.olsson@bi
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/mven03_prel_schema_ht20_webb.pdf - 2026-07-17
Schema höstterminen 2021 Kurs: MNXD11 Hållbar utveckling för jorden, livet och miljön Kursansvarig: Helena Hanson Lokaler: Online i verktyget Zoom Litteratur: Studera på Lunds universitet: Information till studenter på Lunds universitet Studieteknik: Läs om studieverkstaden Studenträttigheter: Läs om dina rättigheter och skyldigheter som student Pedagogiskt stöd: Läs om pedagogiskt stöd vid funkti
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/2021-06/Schema%20MNXD11%20HT21.pdf - 2026-07-16
This thesis takes its starting point in the Green Paper on the Modernisation of EU Public Procurement Policy Towards a More Efficient European Procurement Market, in which the Commission made interesting remarks concerning the interlinks between the Union’s 2020 Strategy, public procurement and State aid. Assessing these interlinks have been an objective of this thesis. As for public procurement a
This study explores how different types of information can support fire service operations during fire incidents through the concept of Smart Firefighting. Semi-structured interviews with 47 incident commanders across three countries have been applied to examine how different types of information (pre-planned, real-time, and predictive) affect decision-making. The findings strongly indicate that r
Radiolabelled monoclonal IgM rheumatoid factors, four from patients with type II essential cryoglobulinaemia and one originating from a patient with rheumatoid arthritis, were tested for binding to group A, B, C and G streptococci and Escherichia coli. Two of the preparations exhibited different binding patterns for the streptococci, whereas the remaining three were not reactive. The binding of on
https://www.msf.lu.se/formular/registration - 2026-07-15
