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Many seriously ill and frail older people experience a lack of practical support and meaningful social engagement. While healthcare provides good medical support, it lacks the full competence and resources to help with social, practical and existential challenges that can arise near the end-of-life. Increasingly, resources in civil society are enlisted to fill this care gap. One such attempt to br
A method of removing radiolabeled monoclonal antibodies (mAbs) from blood using a device external to the body, termed extracorporeal affinity-adsorption (EAA), is being evaluated as a means of decreasing irradiation of noncancerous tissues in therapy protocols. The EAA device uses an avidin column to capture biotinylated-radiolabeled mAbs from circulated blood. In this investigation, three trifunc
Den 1 juli 2018 trädde den nya förvaltningslagen (2017:900) i kraft. I lagen ges enskilda, genom införandet av en dröjsmålstalan, för första gången i svensk förvaltningsrätt en generell rätt att föra talan mot förvaltningsmyndigheters passivitet. Om unionsrätten inte anger annat kommer den nya dröjsmålstalan, enligt principen om medlemsstaternas processuella autonomi, att tillämpas även vid förval
Perceptions have the capacity of indirectly shaping agendas and affecting behaviours. It is a concept briefly touched upon in peacebuilding research, as a tool of tracing dominant practices of international interveners. This paper aims to contribute to this literature, by analysing how perceptions of the UN relate with lacking local agency in peacebuilding practice. In a case study of MONUC’s inte
Titel: Det svenska börsintroduktionspusslet Seminariedatum: 17/01/2020 Kurs: FEKH89 Kandidatuppsats i Finansiering, 15hp Författare: Carl-Magnus Andersson, Josephine Nilsson, Nicholas Wikman Handledare: Maria Gårdängen Nyckelord: IPO, Underprissättning, Långsiktig underprestation, Förstadagsavkastning, Cyklikalitet, Nasdaq OMX Main Market, BHAR Syfte: Att undersöka förekomsten av underprissättning
To continue the development of novel therapeutics to treat bladder cancer, a reliable model for preclinical testing of treatments and studying of the disease mechanism is essential. Ex vivo culturing of precision cut tumor slices (PCTS) provides a model that can retain the tumor architecture and its tumor microenvironment including the immune cell compartment, but data on PCTS based on bladder tum
In pursuit of energy efficiency and sustainable development, goals have been set by the EU and Sweden to improve the energy performance of buildings and reduce their environmental impact. Renovating the existing building stock is a path to achieving the energy and climate goals. This study investigates and analyses various retrofitting options for multifamily residential buildings in Skåne, Sweden
ATP and ADP inhibit, in varying degrees, several dehydrogenases of the central carbon metabolism of Lactococcus lactis ATCC 19435 in vitro, i.e. glyceraldehyde-3-phosphate dehydrogenase (GAPDH), lactate dehydrogenase (LDH) and alcohol dehydrogenase (ADH). Here we demonstrate mixed inhibition for GAPDH and competitive inhibition for LDH and ADH by adenine nucleotides in single inhibition studies. T
The resistance of human immunodeficiency virus type 1 (HIV-1) to antibody-mediated immunity often prevents the detection of antibodies that neutralize primary isolates of HIV-1. However, conventional assays for antibody functions other than neutralization are suboptimal. Current methods for measuring the killing of virus-infected cells by antibody-dependent cell-mediated cytotoxicity (ADCC) are li
Three large-scale Echovirus (E) epidemics (E4,E16,E30), each differently associated to the acute development of diabetes related autoantibodies, have been documented in Cuba. The prevalence of islet cell autoantibodies was moderate during the E4 epidemic but high in the E16 and E30 epidemic. The aim of this study was to evaluate the effect of epidemic strains of echovirus on beta-cell lysis, beta-
The transition quadrupole moments. Q(t), of four weakly populated collective bands up to spin similar to 65h in Er-157,Er-158 have been measured to be similar to II eb demonstrating that these sequences are associated with large deformations. However, the data are inconsistent with calculated values from cranked Nilsson-Strutinsky calculations that predict the lowest energy triaxial shape to be as
Host defense peptides have recently gained much interest as novel anti-infectives owing to their ability to kill bacteria and simultaneously modulate host cell responses. The cationic host defense peptide GKY25 (GKYGFYTHVFRLKKWIQKVIDQFGE), derived from the C terminus of human thrombin, inhibits proinflammatory responses in vitro and in vivo, but the mode of action is unclear. In this study, we sho
Background: Functional and morphological changes of the heart influence blood flow patterns. Therefore, flow patterns may carry diagnostic and prognostic information. Three-dimensional, time-resolved, three-directional phase contrast cardiovascular magnetic resonance (4D PC-CMR) can image flow patterns with unique detail, and using new flow visualization methods may lead to new insights. The aim o
The ATLAS detector at the LHC is used to search for high-mass states, such as heavy charged gauge bosons (W'), decaying to a charged lepton (electron or muon) and a neutrino. Results are presented based on the analysis of pp collisions at a center-of-mass energy of 7 TeV corresponding to an integrated luminosity of 4.7 fb(-1). No excess beyond Standard Model expectations is observed. A W' with Seq
Dorsal agenesis of the pancreas is a rare congenital disorder. We report a case of a 65-year-old man with mild abdominal pain and insulin-dependent diabetes mellitus. Computed tomography (CT) of the abdomen showed a short pancreas with no pancreatic tissue ventral to the splenic vein. Magnetic resonance cholangiopancreatography (MRCP) visualized the absence of a dorsal duct system and confirmed th
Elevated cystatin C in blood reflects impaired glomerular filtration rate (GFR), but current cystatin C assays, based on polyclonal antibodies and immunoturbidimetric or nephelometric detection, have several limitations. We evaluated a new immunoassay based on monoclonal antibodies in samples from patients with and without chronic kidney disease (CKD). The study enrolled 170 men without known CKD
Populärvetenskaplig sammanfattning: Sedimentära facies och fauna från den sensiluriska Bjärsjölagårdkalkstenen i Skåne. Under den sena delen av silurperioden, för ca 420 miljoner år sedan, låg Sverige söder om ekvatorn och Skåne var täckt av ett grunt, varmt hav. I det här havet, den så kallade Baltiska bassängen, bildades sediment som vi idag återfinner bl.a. i ett gammalt övergivet kalkbrott i BThe late Ludlow Bjärsjölagård Limestone Member comprises a part of the Klinta Formation of the Öved-Ramsåsa Group in Skåne, southern Sweden. The ~25 m thick member was formed during the time of the globally known Lau Event and a major sea-level lowstand in the Baltic Basin. This study describes the sedimentary rocks, and their fossil fauna, of the Bjärsjölagård Limestone Member exposed in the Bjär
This paper takes a point of departure in the municipality of Copenhagen (two administrations herein) and their participation in Eurocities. The main question is what kind of processes of Europeanization that takes place in the two administrations. Furthermore, it will be discussed what kind of approach they are taking to European cooperation and how their perception and reflection on the matter is
