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Time-resolved photoluminescence is a validated method for tracking the photoexcited carrier dynamics in luminescent materials. This technique probes the photoluminescence decays upon a periodic excitation by short laser pulses. Herein, we show that this approach cannot directly detect hidden photoexcitations with much slower dynamics than the photoluminescence decay. We demonstrate a new method ba
Pollinators have been negatively impacted by agricultural intensification, loss of natural habitats and habitat fragmentation. This has raised concern about the persistence of plant species dependent on insect pollination in semi-natural grasslands where these are remnants of larger grazed areas, now surrounded by intensive agriculture and forests. To better understand landscape composition effect
High-acoustic-energy-density acoustofluidic devices are necessary to make this technology a viable option for clinical applications in the biomedical field. We present a mechanical interface that enables delivery of a high-amplitude acoustic field inside a fluid cavity by translating the vibrations from two large piezoelectric elements into a microfluidic chip. The study comprises both experimenta
In this letter, we demonstrate low-frequency noise (LFN) characterization of an InAs vertical gate-all-around hafnium-zirconium oxide (HZO) ferroelectric field-effect transistor (FeFET). The LFN characteristics are investigated before and after ferroelectric switching for up to 1000 cycles in the FeFET. The evolution of such cycling reveals distinct differences in the LFN for the two polarization
The interaction of light with matter played a key role in the establishment of quantum mechanics, and each development of new light sources led to important advances in science, technology and society. An exciting area of physics has been opened with the new millennium, attosecond physics, where the motion of electrons can be studied at the fastest time scale ever reached with light. We review the
The instability of metal halide perovskites limits the commercialization of solar cells despite their impressive efficiencies. This instability, driven by photo-induced ion migration, leads to material restructuring, defect formation, degradation, and defect healing. However, these same “unwanted” properties enable to propose Correlation Clustering Imaging (CLIM), a technique that detects local ph
Purpose: Use of mechanical imaging (MI) as complementary to digital mammography (DM), or in simultaneous digital breast tomosynthesis (DBT) and MI - DBTMI, has demonstrated the potential to increase the specificity of breast cancer screening and reduce unnecessary biopsies compared with DM. The aim of this study is to investigate the increase in the radiation dose due to the presence of an MI sens
Steadily increasing use of computer-generated models sets high demands on the realistic representation of breast tissue and abnormalities. Previously, we demonstrated the use of Perlin noise to simulate breast lesions. Now, we expand the previous model by simulating heterogeneous lesion composition. We demonstrate a new approach to simulating 3D soft tissue lesions, with additional benefits of Per
Nowadays organisms encounter not only natural challenges from predators but also significant anthropogenic stressors, such as insecticides, which can profoundly disrupt their normal growth and behavior. However, the knowledge on their potential interactions remains largely unknown, particularly regarding how insecticides may affect predator-prey interactions and prey responses across multiple gene
The onset and development of Alzheimer’s disease is linked to the accumulation of pathological aggregates formed from the normally monomeric amyloid-β peptide within the central nervous system. These Aβ aggregates are increasingly successfully targeted with clinical therapies at later stages of the disease, but the fundamental molecular steps in early stage disease that trigger the initial nucleat
Soil aggregate stability has been asserted as an indicator of soil quality. Earthworms are essential for the stability of soil aggregates due to their activities, including burrowing and organic matter decomposition. In this study, we focused on how differences in plant litter quality influences earthworm abundance and composition and, subsequently, macroaggregate stability in an agroforestry ecos
Background: Guidelines recommend neoadjuvant chemotherapy (NAC) and radical cystectomy (RC) for muscle-invasive bladder cancer (MIBC). Current recommendations do not consider genomic profiles, although the Basal/Squamous (Ba/Sq) subtype is less likely to respond to NAC compared to Urothelial-like (Uro) and Genomically Unstable (GU) subtypes. The aim of this study is to perform cost-effectiveness a
Globally, 3 billion people rely on solid biomass fuel for their everyday cooking, most often using inefficient cooking practices, leading to high exposure levels of household air pollution. This is subsequently associated with negative health and climate impact. Further, the inefficient use of biomass fuels applies pressure on natural forests, resulting in deforestation, loss of biodiversity, and
We present a novel method for in-line acoustofluidic separation of cancer cells directly from whole blood. We report for the first time the observation that blood cells can self-organize when packed closely together in an acoustic field. We utilize this effect to enrich K-562 cancer cells and white blood cell subpopulations from whole blood at normal hematocrit levels. Further, we investigate the
The David Jonas Festschrift is a collection of 67 contributions that cover the latest developments and applications in multidimensional and ultrafast spectroscopies, spanning a wide range of topics. The editorial provides background and summarizes the contributions to the special issue across the areas of experimental advances, theory and computation, proteins and biological systems, nanomaterials
The initiation of adaptive immunity requires antigen presentation in immune inductive sites. Classical dendritic cells (cDC) sense peripheral immune response inducing cues and migrate to the tissue-draining lymph nodes upon engagement, where they present acquired antigen to cognate T cells. Vaccines include adjuvants, which enable cDC activation and migration, both essential steps in the cascade l
Methylammonium lead iodide (MAPbI3) is a prototypical soft-lattice semiconductor whose orthorhombic and tetragonal polymorphs can coexist and interconvert under optical excitation or changes in temperature. The mixed-phase regime attracts attention because of the carrier transfer between phases, which enables optoelectronic functionalities such as optical gain. Here, we investigate carrier dynamic
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in Type 1 Diabetes (T1D), but a subset of individuals remains free from macrovascular or renal complications despite decades of hyperglycaemia and a significant risk factor burden. We used a targeted proteomic approach (Olink Cardiovascular panel III, targeting 92 proteins) to characterize the proteomic profile of cardiov
Aims/hypothesis: Sleep duration is a risk factor for incident diabetes mellitus and CHD. The primary aim of the present study was to investigate, in sex-specific analyses, the role of incident diabetes as the possible biological mechanism for the reported association between short/long sleep duration and incident CHD. Considering that diabetes is a major risk factor for CHD, we hypothesised that a
