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Towards a holistic user innovation policy

This paper aims to synthesize previous user innovation policy proposals into an adapted systems of innovation framework, on which a future holistic user innovation policy for the household sector can be based. We do this in three steps. First, we introduce the systems of innovation framework as a comprehensive basis for a holistic approach to innovation policy. Second, we identify and review polic

Delegation Decisions in Finance

Based on an online experiment with a sample of finance professionals and participants from the general population (acting as clients), we examine drivers and motives of clients’ choices to delegate investment decisions to agents. We find that clients favor delegation to investment algorithms, followed by delegation to finance professionals compensated with an aligned incentive scheme, and lastly t

Favorable fatty acid composition in adipose tissue in healthy Iraqi- compared to Swedish-born men - a pilot study using MRI assessment

Middle Eastern immigrants are at high-risk for insulin resistance. Fatty acid composition (FAC) plays an important role in the development of insulin resistance but has not been investigated in people of Middle Eastern ancestry. Here, the aim was to assess the FAC in visceral and subcutaneous adipose tissue (VAT and SAT) in healthy Iraqi- and Swedish-born men using a magnetic resonance imaging (MR

George Montandon, the Ainu and the Theory of Hologenesis

In 1909, Italian zoologist Daniele Rosa proposed a radical new evolutionary theory: hologenesis, or simultaneous, pan-terrestrial creation and evolution driven primarily by internal factors. Hologenesis was widely ignored or rejected outside Italy, but Swiss-French anthropologist George Montandon eagerly embraced and developed the theory. An ambitious careerist, Montandon’s deep investment in an o

Circulating Tumor Cell Kinetics and Morphology from the Liquid Biopsy Predict Disease Progression in Patients with Metastatic Colorectal Cancer Following Resection

The liquid biopsy has the potential to improve current clinical practice in oncology byproviding real-time personalized information about a patient’s disease status and response to treatment. In this study, we evaluated 161 peripheral blood (PB) samples that were collected aroundsurgical resection from 47 metastatic colorectal cancer (mCRC) patients using the High-DefinitionSingle Cell Assay (HDSC

Interfacing antibody-based microarrays and digital holography enables label-free detection for loss of cell volume

We introduce the combination of digital holographic microscopy (DHM) and antibody microarrays as a powerful tool to measure morphological changes in specifically antibody-captured cells. The aim of the study was to develop DHM for analysis of cell death of etoposide-treated suspension cells. Results/methodology: We demonstrate that the cell number, mean area, thickness and volume were noninvasivel

Learning control for flex-fuel CI engine and fuel cell

This thesis investigated the modeling and control problems in the context of the flex-fuel compression-ignition (CI) engine and fuel cell, which shows great potential in the transition from fossil fuel to renewable energy sources.The modeling parts included the flex-fuel engine combustion process and intake system, and the system scale fuel cell model.The flex-fuel engine gas system models describ

Parkinson's disease and multiple system atrophy patient iPSC-derived oligodendrocytes exhibit alpha-synuclein-induced changes in maturation and immune reactive properties

Significance Our results demonstrate the existence of early cellular pathways and network alterations in oligodendrocytes in the alpha-synucleinopathies Parkinson's disease and multiple system atrophy. They further reveal the involvement of an immune component triggered by alpha-synuclein protein, as well as a connection between (epi)genetic changes and immune reactivity in multiple system atrophy

Deformation and initial breakup morphology of viscous emulsion drops in isotropic homogeneous turbulence with relevance for emulsification devices

This study uses numerical experiments to investigate initial breakup morphology for conditions similar to those experienced in an emulsification device (e.g., a high-pressure homogenizer) (Reλ = 33, We = 1–30, μD/μC = 22, ρD/ρC = 0.9, D/η = 22). Results show breakup consisting of two phases: and ‘oscillatory phase’ where the drops are periodically deforming and relaxing, followed by a ‘critical de

Remote sensing for forest management in semi-arid environments

The aim of the study is to (i) evaluate a method, based on the normalized difference vegetation index (NDVI) calculated from Landsat TM data, for estimation of tree canopy cover in semi-arid environments and (ii) determine canopy cover changes in a forest area in the Sudan by applying the method on Landsat MSS data from 1972 and 1979. Primarily, the NDVI based method was applied on NDVI values, ca

Delineating the intra-patient heterogeneity of molecular alterations in treatment-naïve colorectal cancer with peritoneal carcinomatosis

In a non-negligible number of patients with metastatic colorectal cancer (mCRC), the peritoneum is the predominant site of dissemination. Cure can be achieved by cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC), but this procedure is associated with long-term morbidity and high relapse rates. Thus, there is a pressing need for improved therapeutic strategies and co

Parasitological Assessment of Sewage Sludge Samples for Potential Agricultural Reuse in Tunisia

Wastewater sludge represents an important resource for reuse in agriculture. However, potentially harmful pathogens are a main threat in this context. Thus, the aim of this study was to examine the presence of helminth ova and protozoan cysts in dried sewage sludge samples collected from ten wastewater treatment plants (WWTPs) located in eight governorates in Tunisia. Based on morphological criter