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A powerful new NMR technique applied to the ubiquitous Ca2+ sensor, calmodulin, reveals significant conformational flexibility within each globular domain, which contributes to its ability to bind a wide range of targets. These measurements of residual dipolar couplings between nuclear spins demonstrate a fast and accurate method for pinpointing structural features that cannot be delineated reliab
During 1956 through 1987, 96,891 children have been screened for neonatal hip instability according to the tests of Ortolani and Barlow. In 1956 through 1972 only 4/58, 759 (0.07 permille) were missed, whereas during 1980 through 1987, 12/19, 398 (0.6 permille) were missed. This increase is not caused by any formal alteration of the screening programme. The screening has prevented a late diagnosis
En pilotstudie som innefattade en frågeundersökning på några arbetsplatser och en fältstudie på en av dessa arbetsplatser genomförde's under vintern 1997/98. Studien hade som syfte att sammanlänka laboratorieresultat med resultat under verkliga arbetsförhållanden och att kartlägga problem för individer vid utomhusarbete vintertid. Frågeformulären besvarade's av 43 hamnarbetare, mast- och teletekniDésirée Gavhed, Kalev Kuklane, Eva Karlsson, Ingvar Holmér. A pilot study on work in the cold - questionnaire survey and field study. Arbetslivsrapport 1999:4. A pilot study regarding work in cold conditions was performed during the winter period 1997-1998. The study comprised two parts, a questionnaire survey and a set of field measurements. The purpose of the study was to link laboratory studies
We consider resource allocation with separable objective functions defined over subranges of the integers. While it is well known that (the maximisation version of) this problem can be solved efficiently if the objective functions are concave, the general problem of resource allocation with functions that are not necessarily concave is difficult. In this article, we focus on a large class of probl
The thesis aims at deconstructing the sustainable tourism paradigm: can tourism be "a global strategy for sustainable development", as the tourist industry claims? And will developing countries in particular profit from tourism development?To most international organizations and institutions (from the World Wide Fund for Nature to The World Bank), tourism, if carefully managed, is a positive, sust
In the fusion-evaporation reaction Ca-40+Mg-24 at 104 MeV beam energy, excited states have been observed for the first time in the isotope Ga-31(61)30. The experimental setup comprised the Ge array CLARION, a recoil mass spectrometer and, in its focal plane, an ionization chamber. Five transitions in Ga-61 are identified, out of which a cascade of three transitions has been established by means of
alpha-Ketoglutarate, employed to treat mild chronic renal insufficiency, was obtained through enzymatic oxidation of monosodium glutamate (MSG) catalyzed by L-glutamate dehydrogenase (L-gluDH) coupled with NADH oxidase for the regeneration of NADH back to NAD(+). The irreversible reduction of molecular oxygen to water by NADH oxidase is demonstrated to drive oxidation of MSG to alpha-ketoglutarate
In today's world, there is an increasing trend towards the use of renewable, cheap and readily available biomass in the production of a wide variety of fine and bulk chemicals in different biorefineries. Biorefineries utilize the activities of microbial cells and their enzymes to convert biomass into target products. Many of these processes require enzymes which are operationally stable at high te
All service control nodes, for example Web sites or Mobile Switching Centers, can be modeled as server systems with one or more servers processing the incoming requests. To avoid overload at the service control node different types of admission control mechanisms are usually implemented. In this paper we discuss, from a control point of view, the modeling of a service control-node. The queue is as
A systematic review of radiation therapy trials in several turnout types was performed by The Swedish Council of Technology Assessment in Health Care (SBU). The procedures for evaluation of the scientific literature are described separately (Acta Oncol 2003; 42: 357-365). This synthesis of the literature on radiation therapy for rectal cancer is based on data from 42 randomized trials and 3 meta-a
Despite current efforts to combat HlV/AlDS through behavioural change, ingrained socio-cultural practices such as widow inheritance in south-western Uganda has not changed. Low education, unemployment, dowry, widows' socioeconomic demands and the inheritor's greed for the deceased's wealth, influence widow inheritance. Voluntary counselling and testing is needed for the widows and their inheritors
The dynamics of photoinduced electron injection and recombination between all-trans-8'-apo-beta-caroten-8'-oic acid (ACOA) and a TiO2 Colloidal nanoparticle have been studied by means of transient absorption spectroscopy. We observed an ultrafast (similar to360 fs) electron injection from the initially excited S-2 state of ACOA into the TiO2 conduction band with a quantum yield of similar to40%. A
The interaction between localized and extended vibrational modes in solids is of central importance in understanding how local vibrational modes (LVMs) decay into phonons. In this study, we have investigated interstitial oxygen (O-i) in silicon as a model 'laboratory' for such local-extended mode interactions. Using hydrostatic pressure and infrared spectroscopy, we brought the stretch mode of O-1
