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Objectives To investigate how patients undergoing allo-HCT experience preparedness for self-care and the transition to post-hospital recovery, after using the Assessment of Rehabilitation Needs Checklist (ARNC) in combination with a conversation in a nurse-led intervention. Methods Patients were recruited between March and September 2023, at two allo-HCT centres in Sweden. A convergent parallel mi
Background: Previous studies on contact allergy to diabetes medical devices (MDs) are based on patients referred for patch testing due to suspected allergic contact dermatitis. Objectives: To present real-world data on contact allergy to MD allergens among diabetes MD users. To suggest a MD patch test series. Methods: Adults with type 1 diabetes using diabetes MDs followed up at two endocrinology
Purpose: To study the incidence and subtype of breast cancer in relation to incident and prevalent statin use in a contemporary Swedish prospective cohort, The Karolinska Mammography Project for Risk Prediction of Breast Cancer, KARMA. Methods: A total of 35,315 postmenopausal women attending mammography and included in the KARMA cohort (Jan 2011–March 2013) with data on statin use and potential c
Millimeter-wave Frequency-Modulated Continuous Wave (FMCW) radar enables non-contact heartbeat monitoring by sensing micrometer-level chest vibrations; however, its performance is often severely affected by non-stationary interferences such as electromagnetic pulses and involuntary limb micromovements. These interferences exhibit transient and non-stationary characteristics that are fundamentally
Background and objective Bullying among adolescents is a growing public health concern with serious mental, emotional, and social well-being consequences. This study aims to assess prevalence of physical and cyberbullying among school-going adolescents (13–17 years) in Himachal Pradesh, India, and identify risky and protective factors using an ecological framework descriptively. Methods A cross-se
We present a generic way to obtain level lower bounds for (promise) CSP hierarchies from degree lower bounds for algebraic proof systems. More specifically, we show that pseudo-reduction operators in the sense of Alekhnovich and Razborov [Proc. Steklov Inst. Math. 2003] can be used to fool the cohomological k-consistency algorithm. As applications, we prove optimal level lower bounds for c vs. ℓ-c
Theoretical and empirical studies of reinforcement have advanced our understanding of speciation, yet its role in polymorphic species remains understudied. Because morphs differ in behavior, morphology, and reproductive strategies, reinforcement may act unevenly among them, generating asymmetric reproductive isolation. We tested this prediction in the polymorphic damselflies Ischnura elegans and I
Activation of the kynurenine pathway (KP) with resulting accumulation of neuroactive metabolites may be a downstream pathophysiological mechanism of inflammatory depression. The aims of this study were to investigate KP metabolites in inflammatory depression compared to non-inflammatory depression and healthy controls, and whether these metabolites change with nutraceutical interventions with pote
An experiment to search for new excited states in the proton-rich nucleus57Cu was performed at the Heavy Ion Laboratory of the University of Warsaw. This nucleus, with one valence proton outside the doubly magic56Ni core, offers a sensitive test of Shell Model predictions in interplay with collective effects, and its structure is essential for the production of heavier elements in the astrophysica
International research collaboration is essential for tackling global challenges, many of which disproportionately affect low- and middle-income countries (LMICs), while scientific capital remains concentrated in high-income countries (HICs). Drawing on CRediT contributorship data from 2018–2023 and past and present author affiliations, we examine how labor is divided in teams between researchers
There are fungi whose delectability and even whose shift from toxicity to edibility depends on preparation in the kitchen. The milkcaps Lactarius rufus and Lactarius trivialis and the false morel Gyromitra esculenta are three such mushrooms. The former two will burn your tongue if nibbled raw, and may bring on stomach-ache if not boiled prior to further cooking. The latter could kill you if it is
The visual system can exploit knowledge about temporal contexts in two ways. Attractive serial dependence (SD) can facilitate stability by biasing current stimulus judgments toward recent stimulus history, while repulsive SD can promote change detection by biasing current judgments away from recent stimulus history. This study investigated the co-occurrence of repulsive and attractive SD across fa
Domestic outsourcing is often presented as a way to reduce unpaid work, ease work-family conflict, and promote gender equality. However, it remains unclear whether outsourcing domestic services changes how individuals divide their time between paid work, housework, childcare, and other forms of unpaid work. This paper examines the relationship between domestic outsourcing and time use
Fear-based disorders affect millions worldwide, yet current treatments show limited effectiveness for many patients. While mindfulness is increasingly used clinically for anxiety and trauma disorders, the neural mechanisms underlying its effects on fear processing remain unclear. We conducted a randomized controlled trial using 7T fMRI to test whether mindfulness training enhances fear extinction
Selective Serotonin Reuptake Inhibitors (SSRIs) may reach effect concentrations in aquatic environments and disrupt serotonergic signalling in non-target invertebrates, yet mechanistic understanding remains limited. This study aimed to 1) explore the measurability of a key event associated with serotonin reuptake inhibition within a putative Adverse Outcome Pathway for SSRIs, 2) evaluate the feasi
Background Frailty is an important predictor of outcomes in patients with coronary artery disease (CAD) and following transcatheter aortic valve replacement (TAVR). The NOTION-3 (Third Nordic Aortic Valve Intervention) trial demonstrated that performing percutaneous coronary intervention (PCI) in addition to TAVR reduced the risk for major adverse cardiac events (MACE). Whether this benefit applie
The PRICKLE2 gene encodes a protein implicated in the non-canonical Wnt signalling pathway and in the regulation of planar cell polarity, although its precise biological functions remain incompletely understood. To date, only few PRICKLE2 mutations have been reported, and these have been associated with diverse clinical phenotypes, including autism spectrum disorders, epilepsy, and neurodevelopmen
AbstractBackgroundThe increasing prevalence of obesity has led to a rise in bariatric surgery as an effective intervention for weight loss and associated co-morbidities. However, concerns persist regarding increased alcohol consumption after surgery.ObjectivesTo objectively assess long-term changes in alcohol use after bariatric surgery, we used the highly specific alcohol biomarker phosphatidylet
Despite generous welfare and family policies, Sweden has a sizeable positive socioeconomic gradient in fertility; those with higher incomes have more children than those with lower incomes. While this positive socioeconomic gradient in fertility is not a new phenomenon in Sweden, a similar shift towards a positive fertility gradient is more recently seen in other high-income countries as well. Amo
Recent advances in artificial intelligence (AI) have renewed debates about the future of leadership, in particular the nature of the relationship between human leaders and intelligent machines. The literature tends to portrays human-machine relations in complementary terms: the machine does the data analysis and the number crunching while the leader makes the decisions, guided by their unique visi
