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Human cystatin C is a cysteine proteinase inhibitor belonging to the cystatin superfamily, which previously has been shown to inhibit bone resorption in bone organ culture. The aminoterminal segment, Arg8-Leu9-Val10-Gly11 (RLVG), of the single polypeptide chain of cystatin C constitutes an essential part of its inhibitory center. In the present study, the effect of benzyloxycarbonyl-Arg8-Leu9-Val1

Video-on-Demand (VoD) and video sharing services account for a large percentage of the total downstream Internet traffic. In order to provide a better understanding of the load on these services, we analyze and model a workload trace from a VoD service provided by a major Swedish TV broadcaster. The trace contains over half a million requests generated by more than 20000 unique users. Among other

Popular Abstract in Swedish En växt är under hela sin livstid utsatt för angrepp från organismer som helt eller delvis försöker äta den. Allt växtmaterial äts faktiskt upp förr eller senare. När växten är död ser nedbrytare till att inget av det kol som växten under sin livstid tagit upp från luften går till spillo. En intressant ekologisk fråga är varför vår värld (i allmänhet) är grön när det fiThis thesis discusses aspects of feeding habits of moose (Alces alces) and their impact on forest development. The development of forage that is available to moose was studied by sampling the amount of edible biomass on pine and birch trees. A strong relationship was found between foliage (and twig) biomass and tree diameter, which corroborates the hypothesis that sapwood area limits the amount of

Bound to Be Modern is the most comprehensive study to date on the emergence and function of publishers' cloth bindings. It brings together issues of aesthetics, technique, economy, and social change in order to explain why publishers in the 19th century began to have their books bound, and why decorated clothbindings were so successful as the Western world transitioned into modernity. This study

Sheep's fescue, Festuca ovina, is a common grass found all over Eurasia. In populations in southern Sweden some individuals were found to have two copies of the gene for cytoplasmic phosphoglucose isomerase, PgiC. The second copy, PgiC2, was first believed to be a duplicate of the original gene, PgiC1, but comparisons showed that this is not probable. The PgiC2 locus comprises two PgiC2 genes that

Popular Abstract in Swedish Denna avhandling handlar om modeller inom partikelfysik, vilka beskriver naturens minsta beståndsdelar. För att studera dessa små grundläggande byggstenar behöver man hög energi. Desto st ¨orre energi ju mindre avstånd kan man studera. Med höga energier kan man se atomerna, och med ännu högre energier kan man se kärnan och elektronerna, som atomerna består av. Sedan 60-This thesis dealswith the field of high-energy particle physics. It ismainly concernedwith two issues: the “renormalization of effective field theories” and the “detection of hidden sectors”. The first two papers are dedicated to the renormalization issue while the second two deal with the hidden sectors. Renormalization is crucial when one calculates physical observables to a high degree of preci

Electroconvulsive therapy (ECT) is a very efficient treatment for severe depression. However, cognitive side effects have raised concern to whether ECT can cause cellular damage in vulnerable brain regions. A few recent animal studies have reported limited hippocampal cell loss, while a number of other studies have failed to find any signs of cellular damage and some even report that electroconvul

Popular Abstract in Swedish År 2014 är ordet "kolhydrater" för de flesta människor förknippat med kost och olika dieter. Det må vara en viktig aspekt, men dock långt från den viktigaste. Kolhydrater utför nämligen en rad viktiga processer i levande organismer. Av de 200 mest säljande läkemedelsprodukterna på den amerikanska marknaden 2012, har omkring 75 % av dem en aktiva substans som består av sIn my research, I have explored various aspects of acetals and their reactivity. Acetals have a central role in carbohydrate chemistry as an inherent functionality and as versatile protecting groups. The first part of the thesis summarizes results on regioselective reductive openings of benzylidene acetals. We thus used deuterium substituted benzylidene acetals and boranes, to investigate stereose

Eli F. Heckscher found that in 16'th century Sweden: 1) indirect barter was the most common exchange method and 2) monetary exchange was carried out with different coins, none a generally accepted medium of exchange. These findings refute models of the emergence of money, which builds on Jevons and Menger. Heckscher and later Wesley C. Mitchell thought the historical evolution of the exchange syst

This is a study of the Danish nobility in the period 1450-1650. The aim is to show the changes in the socio-economic foundations of this group under advance during the period, and how this corresponded with changes in the methods and articulations which were used to create legitimicy för the nobility and its' resource claims. Among else we can see that the discourse supposed to ground the legitima

Packaging has a significant impact on the efficiency of logistical systems and therefore, improvements in the retail supply chain can be achieved through the integration and development of the systems of packaging and logistics. In order to enable these improvements, models are needed that facilitate evaluations along the supply chain in order to grasp the whole picture and avoid sub-optimisations

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