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Background. Young adults starting kidney replacement therapy (KRT) during childhood and reaching their 18th birthday (i.e. adult survivors of childhood KRT) form a challenging population of interest to nephrologists treating adults, as during this period there will be a transition to adult renal centres. Nonetheless, few studies have focused on the epidemiology of KRT in this group. We aimed to pr

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Background: Monitoring metabolites of tamoxifen, such as endoxifen, has been suggested as a strategy to ascertain therapeutic effect of tamoxifen therapy, but clinical guidelines are missing. Herein, we aim to investigate the outcome of endoxifen concentrations of low-dose tamoxifen, using change in mammographic breast density as a proxy for therapy response. Methods: In the randomized KARISMA-Tam

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Aim: The selective use of defunctioning stomas in anterior resection for rectal cancer hinges on accurately predicting anastomotic leakage. The aim of this study was to develop a prediction model for use in a prospective randomized clinical trial. Method: Colorectal Cancer Database (CRCBaSe) Sweden was used to identify patients who underwent low anterior resection for rectal cancer 2007–2021. Elig

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This chapter examines the integration of VR in teaching, focusing on teachers' experiences, perceptions, and challenges. Using a mixed-methods approach, qualitative data from 156 teachers were analyzed with NLP and AI-driven models. The findings show that VR enhances student engagement, motivation, and experiential learning by making abstract concepts accessible and providing risk-free environment

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Tonåringar utgör en viktig källa till flexibel och lågavlönad arbetskraft inom servicesektorn. Trots detta saknas forskning som belyser och problematiserar deras sysselsättningsmönster, anställningsvillkor och arbetserfarenheter – särskilt i en nordisk kontext. Denna avhandling analyserar gymnasieelever som arbetskraft i Sverige, i skärningspunkten mellan kundnära servicebranscher som är beroende Teenage students constitute an important source of flexible, low-cost labor in interactive service sectors. However, existing empirical research has primarily treated their labor as transitional, focusing on its impact on future employment or labor market outcomes. There remains a lack of knowledge about how these young workers experience and make sense of their early employment, particularly with

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Hand-held power tools with high levels of vibration can give rise to hand–arm vibration syndrome, involving chronic nerve and vascular damage. The objective of this study was to identify aspects that could affect the implementation and future use of low-vibration tools in four types of industries: construction, quarrying, steelworks and dental laboratories. Field visits including observations and

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Om toppmötena i slutet av andra världskriget

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AIMS/HYPOTHESIS: The aim of this work was to explore associations between type 1 diabetes progression from stages 1 or 2 to stage 3 and interacting ligand-receptor complexes of HLA class I (HLA-I) and KIR gene products.METHODS: Applying next-generation sequencing technology to genotype HLA-I genes (HLA-A, -B, -C) and KIR genes (KIR2DL1, KIR2DL2, KIR2DL3, KIR2DL4, KIR2DL5, KIR2DS1, KIR2DS2, KIR2DS3