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Boreal forests mitigate climate change by sequestering atmospheric carbon. Recent declines in the boreal carbon sink and tree growth suggest that this mitigating influence is weakening, yet the underlying drivers remain unresolved. Increasing drought frequency is one likely driver. Yet most studies have focused on managed forests, overlooking the significant but shrinking areas of old-growth fores
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West Nile virus (WNV) is a growing risk to public and veterinary health in Europe, with intensifying outbreaks over recent decades coinciding with a rapidly warming climate. Thermal biology models parameterized through laboratory experiments on the mosquito vectors and the pathogen play a central role in our causal understanding of the effects of temperature on WNV transmission. We evaluated the a
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Introduction – Determining the etiology of community-acquired pneumonia (CAP) is essential for targeted treatment and optimal care. Reliable results require selection of the appropriate sampling site. Methods – Paired nasopharyngeal (NP) and oropharyngeal (OP) swabs were collected from 484 patients with CAP between September 2016 and September 2018. The samples were analyzed by PCRs for Streptococ
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Background – While amyloid-β (Aβ) and tau are hallmark pathologies of Alzheimer’s disease (AD), TDP-43 proteinopathy is increasingly recognized as an important contributor, occurring in up to 57% of AD cases and associated with accelerated cognitive decline. TDP-43 regulates RNA splicing, and its mislocalization leads to cryptic exon inclusion and loss of canonical protein function. While neuronal
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Forest above-ground biomass (AGB) estimation is crucial for evaluating carbon dynamics. Although optical and synthetic aperture radar (SAR) data provide complementary spectral and structural information, limitations in existing fusion approaches restrict AGB estimation accuracy. This study proposes a multi-source data fusion framework comparing two image fusion strategies—the conventional Hue-Inte
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Generative AI promises substantial productivity gains, but many initiatives fail. This column argues that outcomes depend on readiness, not technology alone. We examine AI transformation requirements across organizational, individual, and technological dimensions, highlighting why engineering practices, human factors, and strategic clarity determine success.
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Preeclampsia (PE) is a complication during pregnancy characterized by hypertension, organ damage, and systemic inflammation. Increasing evidence suggests that the gut microbiome may play a role in the pathophysiology of PE. However, previous studies on the gut microbiome have generally overlooked the distinction between subgroups of PE, although clinical manifestations may differ. Also, most studi
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p27, a cyclin-dependent kinase inhibitor, functions as a tumour suppressor in the nucleus but may acquire oncogenic properties when mislocalized to the cytoplasm. While KRAS mutations can induce p27 phosphorylation and cytoplasmic retention, the regulation and significance of p27 expression in wild-type (WT) KRAS colorectal cancer (CRC) remain unclear. This study investigated the relationship betw
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Low- and middle-income countries are expanding health insurance to enhance financial protection. However, there is scarcity of evidence on the stakeholder perceptions towards health insurance. This study explores stakeholders' perceptions towards the implementation of the National Health Insurance Scheme in Zambia. This qualitative study is based on 21 in-depth interviews with key stakeholders inv
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BACKGROUND: Improving utilization of contraceptive methods serves as a powerful catalyst for advancing women's education, health, and personal autonomy. Many countries have pledged to enhance contraceptive availability as part of their commitment to the Sustainable Development Goals (SDGs), specifically under indicator 3.7.1. This study sought to understand the drivers of modern contraceptive use
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Sexual harassment persists in academic workplaces despite extensive policy frameworks. This study explored how employees at a large Swedish university perceive and articulate the organisational culture and everyday norms that shape sexual harassment. Ten focus group discussions were held with forty staff members, separated by managerial role and conducted in Swedish or English. Transcripts were an
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Two protein ingredients, vital wheat gluten (WG) and hempseed protein concentrate (HPC), were extruded both individually and in combination, in a co-rotating twin-screw extruder to produce pilot-scale high-moisture meat analogues. To determine possible textural outcomes, the impact of the ratio between the input materials and operational settings was investigated. Seven different WG and HPC ratios
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Offshore wind farms (OWFs) pose a potential threat to migratory birds, either as a barrier or as a result of lethal collisions. We aimed to demonstrate the temporal and spatial frames for potential mitigation measures for a rare and protected species. We analysed 74 autumn migration tracks for 65 GPS-tagged Caspian terns (Hydroprogne caspia) through an area with operating and planned OWFs. On thei
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We characterized patients with discordant plasma p-tau217 results and amyloid status determined by the Aβ42/p-tau181 CSF ratio or Aβ-PET biomarkers in an ethnically diverse mixed memory clinic cohort. Among 539 patients, 83.9% had concordant biomarker profiles, while 13.4% were amyloid negative and plasma p-tau217 positive discordant, and 2.8% were amyloid positive and plasma p-tau217 negative dis
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Background: The use of patient-reported outcome measures (PROM) can be beneficial in several ways. However, presentations of PROM data from individuals living with, through, or beyond cancer are scarce in the existing scientific literature, and challenges in presenting and interpreting PROM data may be an explanation. Our overall aim was to describe aspects of wellbeing in individuals living with
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The paper explores how Indigenous, Black, and Campesinas women in the Colombian Caribbeantransform everyday practices of care into socio-environmental leadership and territorial defence.Based on oral histories collected through collaborative research on water governance and climatechange, we examine how emotions and ecological knowledge converge in defending land, water, andcollective well-being.
