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Aim: To study the effect of standard of care therapy on antibody response and functionality following immunization with 13-valent pneumococcal conjugate vaccine (PCV13) in patients with primary systemic vasculitis compared to healthy controls. Methods: 49 patients with vasculitis and 49 controls received a single dose (0.5. ml) PCV13 intramuscularly. Ongoing treatments: azathioprine (AZA; n = 11),

This article presents the sensitivity of theATLAS experiment to the lepton-flavour-violating decays of τ → 3μ. A method utilising the production of τ leptons via W → τν decays is used. This method is applied to the sample of 20.3 fb−1 of pp collision data at a centre-of-mass energy of 8 TeV collected by the ATLAS experiment at the LHC in 2012. No event is observed passing the selection criteria,an

Aims: To explore and compare sensitivity and specificity for HbA1c ≥48. mmol/mol as a predictor for type 2 diabetes mellitus (T2DM) in two populations with different ethnicity and to examine the predictive value of two levels of HbA1c (≥42. mmol/mol, ≥39. mmol/mol) for prediabetes in these populations. Methods: Four cohorts were examined with an oral glucose tolerance test. (1) The MEDIM Study (n

Objectives: A history of stroke is common in patients with transient ischemic attack (TIA) and ischemic stroke (IS), but there are few reports characterizing this group of patients. We aimed to compare characteristics, risk factors, and secondary preventive treatment in patients with TIA or IS with vs without a history of stroke. Methods: Hospital-based data on TIA and IS events, registered from J

The production rates of prompt and non-prompt J/ψ and ψ (2S) mesons in their dimuon decay modes are measured using 2.1 and 11.4 fb−1 of data collected with the ATLAS experiment at the Large Hadron Collider, in proton– proton collisions at √ s = 7 and 8 respectively. Production cross-sections for prompt as well as non-prompt sources, ratios of ψ (2S) to J/ψ production, and the fractions of nonpromp

Colonoscopy plays a key role in the work-up of digestive diseases and constitutes the cornerstone in colorectal cancer diagnosis and prevention. Data suggest that the quality of colonoscopy varies widely between different endoscopists. This article summarizes current evidence and expert consensus on quality indicators, along with the evidence supporting their use in benchmarking, quality reporting

We report on two-particle charge-dependent correlations in pp, p–Pb, and Pb–Pb collisions as a function of the pseudorapidity and azimuthal angle difference, Δη and Δϕ respectively. These correlations are studied using the balance function that probes the charge creation time and the development of collectivity in the produced system. The dependence of the balance function on the event multiplicit

Background: Isocyanates are used in polyurethane production. Dermal exposure to isocyanates can induce contact allergy. The most common isocyanate is diphenylmethane diisocyanate used for industrial purposes. The isomer diphenylmethane-4,4'-diisocyanate (4,4'-MDI) is used in patch testing. Diphenylmethane-4,4'-diamine (4,4'-MDA) is its corresponding amine. Concurrent reactions to 4,4'-MDI and 4,4'

Inhibitor development in haemophilia is a serious complication to treatment with factor concentrates. Since the advent of more pure products, especially developed using recombinant DNA technology, some studies have shown an increased incidence of inhibitors in previously untreated patients (PUPs) receiving recombinant products whereas plasmaderived concentrates sometimes have been claimed to have

BACKGROUND - Multiple laboratory tests are used to diagnose and manage patients with diabetes mellitus. The quality of the scientific evidence supporting the use of these tests varies substantially. APPROACH - An expert committee compiled evidence-based recommendations for the use of laboratory testing for patients with diabetes. A newsystemwas developed to grade the overall quality of the evidenc

This paper presents a study of the production of WW or WZ boson pairs, with one W boson decaying to eν or μν and one W or Z boson decaying hadronically. The analysis uses 20.2fb-1 of s=8TeVpp collision data, collected by the ATLAS detector at the Large Hadron Collider. Cross-sections for WW / WZ production are measured in high-pT fiducial regions defined close to the experimental event selection.

This brief presents an operational transconductance amplifier (OTA) linearization technique that is applied to a low-noise amplifier (LNA) and an OTA-C filter. Simulations show the effectiveness of the proposed technique on the LNA, whose noise and gain performance remain unaffected while the linearity is significantly improved. Measurements of the 80-MHz fourth order Butterworth OTA-C filter are

Background: Acute pancreatitis (AP) is a common and potentially severe disease. Early identification of severity grade is crucial for the outcome of the patient. For study approaches and comparison of inter-institutional data the AP patients need to be uniformly classified.The aims of this thesis were to investigate the early stratifiation capacity of biomarkers in AP and to assess the morphologic

Postwar cities demonstrate the most persistent continuities of war in peace. This effectively forces people into divided and politicised lives, undermines city-wide urban dynamics, and hampers wider peace processes that these cities are part of. It, however, also goes against what can be and historically is expected of the city – namely to transcend divides, bridge communities, and foster co-exist

Two major fuels commonly used in compression ignition (CI) and spark ignition (SI) enginesare diesel and gasoline. The reserve of diesel and gasoline is limited, however the combustion ofthese fuels giving rise to air pollution. This calls for the search for alternative fuels, preferablyrenewable fuels, and the development of more efficient and clean combustion technologies forinternal combustion