We present the principle and the first prototypes of a double rotating-crystal monochromator, based on an assembly of smaller rotating elements. Such a device was developed as the key element to implement a parallel-beam modification of the time-focusing technique for neutron spectrometers. This concept is particularly promising for long-pulse sources and can bring specific advantages on continuou

The Beamline for European Materials Engineering Research (BEER) has been recently proposed to be built at the European Spallation Source (ESS). The presented concept of neutron delivery optics for this instrument addresses the problems of bi-spectral beam extraction from a small moderator, optimization of neutron guides profile for long-range neutron transport and focusing at the sample under vari

The Beamline for European Materials Engineering Research (BEER) will be built at the European Spallation Source (ESS). The diffractometer utilizes the high brilliance of the long-pulse neutron source and offers high instrument flexibility. It includes a novel chopper technique that extracts several short pulses out of the long pulse, leading to substantial intensity gain of up to an order of magni

We report on the study of fast-neutron background for the BIFROST spectrometer at ESS. We investigate the effect of background radiation induced by the interaction of fast neutrons from the source with the material of the neutron guide and devise a reasonable fast, thermal/cold neutron shielding solution for the current guide geometry using McStas and MCNPX. We investigate the effectiveness of the

Telecommunication monitoring data requires the automation of data analysis workflows. A data mining tool provides data workflow management systems to process and perform analysis tasks. This paper presents an evaluation of two example data mining tools following the principles of design of experiment (DOE) to run forecasting and clustering workflows for telecom monitoring data. We conduct both qua

It is a public health priority to identify the adverse and non-adverse associations between pharmaceutical medications and cancer. We search for and evaluate associations between all prescribed medications and longitudinal cancer risk in participants of the Swedish Cancer Register (N = 9,014,975). We associated 552 different medications with incident cancer risk (any, breast, colon, and prostate)

Background Children and adolescents with autism spectrum disorder (ASD) or attention-deficit/hyperactivity disorder (ADHD) are more likely to be surrounded by different risk factors. In order to work preventively with decreasing ADHD and ASD symptoms, there is a need of more knowledge concerning risk factors. Objective This study aimed to investigate school, health, lifestyle and social interactio

The ability of light to cause pain is paradoxical. The retina detects light but is devoid of nociceptors while the trigeminal sensory ganglia (TG) contain nociceptors but not photoreceptors. Melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs) are thought to mediate light-induced pain but recent evidence raises the possibility of an alternative light responsive pathwa

Doherty power amplifiers (PAs) can achieve high efficiency with modulated signals since they exhibit an efficiency-peak in backoff that can, in theory, reach full-scale efficiency. Unfortunately, the backoff efficiency of real Doherty PAs is lowered by unavoidable losses. The purpose of this work is to study the potential of re-gaining some of this efficiency loss through nonlinear drive-curve des

The Multi-Grid (MG) detector has been introduced at ILL and developed by a collaboration between ILL, ESS and Linkoping University. This detector design addresses the severely decreased availability of He3, in particular for neutron scattering instruments with large-area detectors, such as time-of-flight neutron spectrometers at ESS and other facilities. The MG detector is based on thin converter

Purpose: Most knowledge regarding outcome after adrenal surgery stems from retrospective studies reported by highly specialized centres. The aim of this study was to report a national experience of adrenalectomy with particular attention to predictive factors for postoperative complications, conversion from endoscopic to open surgery and length of hospital stay. Methods: Adrenalectomies reported i

Background: The production of ethanol and other fuels and chemicals from lignocellulosic materials is dependent of efficient xylose conversion. Xylose fermentation capacity in yeasts is usually linked to xylose reductase (XR) accepting NADH as cofactor. The XR from Scheffersomyces stipitis, which is able to use NADH as cofactor but still prefers NADPH, has been used to generate recombinant xylose-

Background: Swedish studies on antibiotic use in primary care have been based on one-week registrations of infections. In order to study adherence to guidelines, analyses based on large databases that provide information on diagnosis linked prescriptions, are needed. This study describes trends in management of infections in Swedish primary care particularly with regards to antibiotic prescribing

In 2014 the Nordic Council of Ministers initiated a new bioeconomy project: “Test centers for green energy solutions – Biorefineries and Business needs”. The purpose was to strengthen green growth in the area of the bioeconomy by analyzing and mapping the current status of the bioeconomy in the Nordic countries and identify potentials and obstacles, needs and opportunities. Based on this a set of

Randomized controlled trials (RCT) are often underpowered for validating gene-treatment interactions. Using published data from the Diabetes Prevention Program (DPP), we examined power in conventional and genotype-based recall (GBR) trials. We calculated sample size and statistical power for gene-metformin interactions (vs. placebo) using incidence rates, gene-drug interaction effect estimates and

Given a sequence of numbers (Formula presented.) in [0, 1], consider the following experiment. First, we flip a fair coin and then, at step n, we turn the coin over to the other side with probability (Formula presented.), (Formula presented.), independently of the sequence of the previous terms. What can we say about the distribution of the empirical frequency of heads as (Formula presented.)? We

Glycero-3-phosphocholine (GPC), the product of the complete deacylation of phosphatidylcholine (PC), was long thought to not be a substrate for reacylation. However, it was recently shown that cell-free extracts from yeast and plants could acylate GPC with acyl groups from acyl-CoA. By screening enzyme activities of extracts derived from a yeast knock-out collection, we were able to identify and c

Nonverbal behaviour has an important function in team sports, but research is limited. Adopting a psychological momentum (PM) framework, this study explores the relationship between a team’s history of events, nonverbal post-shot celebrations in the form of gestures and touch shown by the shooter after scoring, and subsequent team performance during handball matches. A naturalistic design with sys