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Carbon and nitrogen stable isotope values in freshwater, brackish and marine fish bone collagen from Mesolithic and Neolithic sites in central and northern Europe

The aim of this research is to examine the isotopic characterisation of archaeological fish species as it relates to freshwater, brackish and marine environments, trophic level and migration patterns, and to determine intraspecies variation within and between fish populations in different locations within central and northern Europe. Carbon and nitrogen stable isotope analysis was undertaken on co

Improvement of whole-cell transamination with Saccharomyces cerevisiae using metabolic engineering and cell pre-adaptation

Background: Whole-cell biocatalysis based on metabolically active baker's yeast with engineered transamination activity can be used to generate molecules carrying a chiral amine moiety. A prerequisite is though to express efficient ω-transaminases and to reach sufficient intracellular precursor levels. Results: Herein, the efficiency of three different ω-transaminases originating from Capsicum chi

Experimental methods and modeling techniques for description of cell population heterogeneity

With the continuous development, in the last decades, of analytical techniques providing complex information at single cell level, the study of cell heterogeneity has been the focus of several research projects within analytical biotechnology. Nonetheless, the complex interplay between environmental changes and cellular responses is yet not fully understood, and the integration of this new knowled

Assessing vector navigation in long-distance migrating birds

Birds migrating between distant locations regularly perform long continuous flights lasting several days. What compass mechanism they use is still a mystery. Here, we use a novel approach, applying an individual-based model, taking compass mechanisms based on celestial and geomagnetic information and wind into account simultaneously, to investigate what compass mechanism likely is used during long

Visual navigation in nocturnal insects

Despite their tiny eyes and brains, nocturnal insects have evolved a remarkable capacity to visually navigate at night. Whereas some use moonlight or the stars as celestial compass cues to maintain a straight-line course, others use visual landmarks to navigate to and from their nest. These impressive abilities rely on highly sensitive compound eyes and specialized visual processing strategies in

Incorporating Affective Aspects into Pedagogy

Human-Computer Interaction (HCI) is an umbrella domain for many areas of study. This paper will look at those topics of HCI known as affective aspects. Affective aspects investigate emotional responses that the user communicates, both verbally and physically, when working with a computer including before and after the work is done. This paper examines the question of improving pedagogy and curricu

Solving large instances of the RSA problem in flexgrid elastic optical networks

We present an optimization procedure that mixes advanced large-scale optimization methods and heuristics to solve large instances (with over 1.7 million integer variables) of the routing and spectrum allocation (RSA) problem - a basic optimization problem in flexgrid elastic optical networks. We formulate the problem as a mixed-integer program for which we develop a branch-and-price algorithm enha

Acoustofluidic harvesting of microalgae on a single chip

We present an on-chip acoustofluidic platform for harvesting a target microalgal species from a heterogeneous population of cells and particles based on their size, density, and compressibility in a rapid, non-invasive, energy-efficient, continuously running, and automated manner. For our proof-of-principle demonstration, we use Euglena gracilis as a target species. Specifically, we show the simul

Bats may eat diurnal flies that rest on wind turbines

Bats are currently killed in large numbers at wind turbines worldwide, but the ultimate reason why this happens remains poorly understood. One hypothesis is that bats visit wind turbines to feed on insects exposed at the turbine towers. We used single molecule next generation DNA sequencing to identify stomach contents of 18 bats of four species (Pipistrellus pygmaeus, Nyctalus noctula, Eptesicus

Microsieving in municipal wastewater treatment : Chemically enhanced primary and tertiary treatment

Municipal wastewater treatment plants are constantly forced to make improvements. The main objectives are to reduce energy consumption, to increase the treatment capacity and to improve the effluent water quality. Microsieves in combination with chemical pretreatment can potentially fulfil these objectives. In this work, experiments were mainly conducted at the large pilot scale, and supplementaryMunicipal wastewater treatment plants are constantly forced to make improvements. The main objectives are to reduce energy consumption, to increase the treatment capacity and to improve the effluent water quality. Microsieves in combination with chemical pretreatment can potentially fulfil these objectives. In this work, experiments were mainly conducted at the large pilot scale, and supplementary

The 1501 Ma Kuonamka Large Igneous Province of northern Siberia : U-Pb geochronology, geochemistry, and links with coeval magmatism on other crustal blocks

A new large igneous province (LIP), the 1501 ± 3 Ma Kuonamka LIP, extends across 700 km of northern Siberia and is linked with coeval dikes and sills in the formerly attached Sao Francisco craton (SFC)-Congo craton to yield a short-duration event 2000 km across. The age of the Kuonamka LIP can be summarized as 1501 ± 3 Ma (95% confidence), based on 7 U-Pb ID-TIMS ages (6 new herein) from dolerite

Seasonal trends of Amazonian rainforest phenology, net primary productivity, and carbon allocation

The seasonality of solar irradiance and precipitation may regulate seasonal variations in tropical forests carbon cycling. Controversy remains over their importance as drivers of seasonal dynamics of net primary productivity in tropical forests. We use ground data from nine lowland Amazonian forest plots collected over 3 years to quantify the monthly primary productivity (NPP) of leaves, reproduct

Cochlear Implantation: Exploring Technoscience and Designs on Citizenship

Around the globe more than 350,000 citizens live with a sophisticated hearing aid device called Cochlear Implant. In many countries CI is an institutionalized medical procedure for restoring deafened with a technological sense of hearing but the social challenges for users is a largely unexplored issue. Addressing this social dimension, the article explores how Cochlear Implant works as a boundary