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Current progress of adhesins as vaccine candidates for Moraxella catarrhalis

Moraxello catorrhalis is an emerging pathogen and all isolates are now considered beta-lactamase producing. Potential further use of vaccines against Streptococcus pneumoniae and nontypeable Haemophilus influenzae means that M. catarrhalis might be thrust further into the limelight. However, a vaccine has not yet been designed. In this review, the progress of M. catarrhalis adhesins as vaccine can

Influence of personality disorder features on social functioning in substance-abusing women five years after compulsive residential treatment.

BACKGROUND: Personality disorders (PD) are related to negative outcome in substance abuse treatment, and in the general population, personality disorders are related to negative outcome in overall functioning. Little is known about the impact of PD on adjustment following substance abuse treatment. METHODS: A cohort of 132 women was followed for 5 years after their index treatment episode in compu

A comparison between IEEC, a new biodegradable particulate contrast medium, and iohexol in a tumor model of computed tomography imaging of the liver

RATIONALE AND OBJECTIVES. Higher contrast between normal and pathologic tissues in the liver may enable detection of smaller lesions in computed tomography (CT). This can be obtained using a liver-specific contrast medium. The authors evaluate a new agent, IEEC (1'-Ethyloxycarbonyloxy)-ethyl-5-acetylamino-3-(N-methyl-acetylami no)-2,4,6- triiodo-benzenecarboxylate), in an animal model, as a potent

Separation of Selenium, Zinc, and Copper Compounds in Bovine Whey Using Size Exclusion Chromatography Linked to Inductively Coupled Plasma Mass Spectrometry.

To study the role of trace elements for the quality and nutritional value of bovine milk, the distribution of selenium, zinc, and copper in whey was investigated using a method linking size exclusion chromatography to inductively coupled plasma mass spectrometry (SEC-ICP-MS). Three major peaks were detected for selenium, two peaks for zinc, and five peaks for copper. More than 65% of the selenium

Stress and health among women and men in a Swedish telecom company

The aim of the study was to investigate gender differences at managerial and non-managerial level in perceived stress and control and the relationship to health problems. Questionnaires were collected from 281 women and men at both managerial and non-managerial level in a sales department in a large Swedish telecom company. The results showed only minor differences in perceived stress and no diffe

Small intestinal CD103(+) dendritic cells display unique functional properties that are conserved between mice and humans

A functionally distinct subset of CD103(+) dendritic cells (DCs) has recently been identified in murine mesenteric lymph nodes (MLN) that induces enhanced FoxP3(+) T cell differentiation, retinoic acid receptor signaling, and gut-homing receptor (CCR9 and alpha 4 beta 7) expression in responding T cells. We show that this function is specific to small intestinal lamina propria (SI-LP) and MLN CD10

A key recovery attack on Edon80

Edon80 is a recent stream cipher design that has advanced to the third and last phase of the eSTREAM project. It has remained unbroken and untweaked since it was designed and submitted to eSTREAM. It is now one of the 8 final hardware candidates. In this paper we cryptanalyze the cipher by describing a key recovery attack. The complexity of the attack is around 269 simple operations for a keystrea

Involvement and functional impairment of the CD34(+)CD38(-)Thy-1(+) hematopoietic stem cell pool in myelodysplastic syndromes with trisomy 8.

Clonality studies of mature cells suggest that the primary transformation event in myelodysplastic syndrome (MDS) most frequently occurs in a myeloid-restricted progenitor, a hypothesis supported by recent studies of purified CD34(+)Thy1(+) hematopoietic stem cells (HSCs) in cases with trisomy 8 (+8). In contrast, we recently demonstrated that a lymphomyeloid HSC is the target for transformation i

The selection and application of material planning methods

Methods for planning and control of the flow of material in the manufacturing enterprise are more or less appropriate to use in a specific situation, mainly depending on the existing planning environment. How well they contribute to an effective material flow is also depending on how they are applied. This paper examines which material planning methods companies are using, to what extent these met

Genetic variation and clonal diversity in four clonal sedges (Carex) along the Arctic coast of Eurasia

We studied the structure of genetic variation (at both ramet- and genet-level) and clonal diversity within and among populations in the four closely related arctic clonal sedges Carex bigelowii, C. ensifolia, C. lugens and C. starts by use of allozyme markers. Compared to other sedges and arctic plants, the studied taxa all had high levels of genetic variation, both within populations and taxa. Th

Structure estimation and surface triangulation of deformable objects

A system is developed that from an image sequence of a deformable object automatically extracts features and tracks them through the sequence, estimates the non-rigid 3D structure and finally computes a surface triangulation. Also the camera motion is acquired. The object is supposed to deform according to a linear model, while the motion of the camera can be arbitrary. No domain specific prior of

Genetic and phenotypic associations in morphological traits: a long term study of great reed warblers Acrocephalus arundinaceus

We present estimates of standardized selection (directional and quadratic) differentials via reproductive success on eight morphological traits in a newly founded long-term study population of great reed warblers Acrocephalus arundinaceus in Sweden. In order to predict the evolutionary response to selection in these traits we present estimates of heritabilities (h(2)), phenotypic (r(P)) and geneti

Proteoglycans and hyaluronan in human fetal membranes

OBJECTIVE: The aim of this study was to describe the distributions of major extracellular matrix components, such as proteoglycans, collagen acid hyaluronan, in the fetal membranes at term. STUDY DESIGN: Fetal membranes were obtained from elective cesarean deliveries at term. Guanidinium extracts were analyzed for proteoglycans with alcian blue precipitation, sodium dodecyl sulfate-polyacrylamide

Randomized study to evaluate the use of high-dose therapy as part of primary treatment for "aggressive" lymphoma

Purpose: This trial of the German High-Grade Non-Hodgkin's Lymphoma Study Group compares the use of high-dose therapy (HDT) as part of primary treatment with cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) plus etoposide followed by involved-field (IF) radiotherapy in a randomized, multicenter, phase III study. Patients and Methods: Three hundred twelve patients with "aggressive"