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Dendrokronologisk analys av fastigheten Lunda 8:2, Lunda socken, Nyköping
Allra sämst är överskriftsrubriker
In the Swedish contemporary media landscape, marked by limited financial resources, many local newspapers are searching for sustainable business models. This reality brings an unprecedented challenge: finding a balance between the market-driven demands of economic efficiency and audience expectations of trustworthy local news. A way of doing this is by writing captivating headlines that appeal to
Local staging of de novo prostate cancer using mpMRI, PSMA-PET and PSMA-PET/mpMRI – a comparative study
Background: Accurate diagnosis and staging are essential for optimal treatment planning of prostate cancer. By combining functional and anatomical imaging, PSMA-PET/mpMRI offers a potential to improve lesion detection and enhance staging accuracy. This study aimed to evaluate the diagnostic performance of lesion detection and local staging of prostate cancer using combined PSMA-PET/mpMRI compared
Flow of microgels with different softness at the interface reproduced by a multi-Hertzian model
Once surface active colloids, such as microgels, adsorb to an interface, they modify the viscoelastic properties of the interface. In contrast to what happens in bulk, the elastic properties have a non-monotonic dependence on the generalized area fraction. In this study, we describe this phenomena by performing molecular dynamic simulations of effective pair potentials in two dimensions. Our poten
Differences in sexual violence against younger and older adults in complex humanitarian settings : a retrospective analysis from Médecins Sans Frontières in 2019-24
BACKGROUND: Sexual violence against older adults in humanitarian settings is poorly documented, leading to gaps in prevention and delivery of support services. This study aimed to document differences in assault characteristics between younger and older adults, by sex and displacement and disability status and region. METHODS: This retrospective, descriptive observational, multi-country study incl
Migration of Cemented and Uncemented Implants in Total Knee Arthroplasty with an Asymmetrical Tibial Component : A Randomized Controlled Trial with a 2-Year Model-Based Radiostereometric Analysis Follow-up
Background:Aseptic loosening remains a main complication following total knee arthroplasty (TKA), requiring revision surgery. Radiostereometric analysis (RSA) can assess the risk of aseptic loosening. This study evaluated the migration and segmental motion of cemented and uncemented femoral and asymmetrical tibial Persona components (Zimmer Biomet) with model-based RSA.Methods:We conducted a rando
Effects of daylength manipulation on migratory activity and fuelling in a long-distance nocturnal songbird migrant
Migratory birds have evolved a multitude of physiological and behavioural adaptations to reach their population-specific wintering areas during their first migration. The endogenous program encodes distance, direction and fuelling, and involves species-specific adaptations leading naïve migratory birds along highly diverse routes. While daylength has been extensively studied in relation to the ons
Restarting anticoagulation early versus late in patients with chronic subdural hematoma and atrial fibrillation (RELACS) : a phase III international multicenter, randomized controlled, two-arm, assessor-blinded trial
Background: Chronic subdural hematoma (CSDH) is a rapidly growing neurosurgical condition, driven primarily by an aging population and the increasing use of antithrombotic medications. Approximately 25% of CSDH patients are on anticoagulants due to atrial fibrillation (AF). The postoperative management of these patients presents a significant clinical challenge, as clinicians must balance the risk
Dynamics and MicroRNA144/451-mediated mechanisms of regulatory B Cells during Schistosoma japonicum infection in Mice
Schistosoma japonicum (S. japonicum) infection and soluble egg antigens (SEA) can induce various immune responses, including the generation of IL-10-producing regulatory B cells (Bregs). This study investigated the dynamic changes and induction mechanisms of Bregs during S. japonicum infection. We demonstrated that CD19+IL-10+Bregs and CD19+Tim-1+ Bregs secreting IL-10 gradually increased from 6 t
Non-local X-ray intermolecular radiative decay probes solvation shell of ions in water
Aqueous solutions are crucial in chemistry, biology, environmental science, and technology. The chemistry of solutes is influenced by the surrounding solvation shell of water molecules, which have different chemical properties than bulk water due to their different electronic and geometric structure. It is experimentally challenging to selectively investigate this property-determining electronic a
ISFJORD RADIO SHIPS AND BOATS : From sailcloth dinghies to Battleships
TRPM3 activation causes CGRP release in trigeminal neurons : Implications for migraine mechanisms
Background: The transient receptor potential melastatin 3 (TRPM3) ion channel has been implicated in sensory modulation and pain transmission and may contribute to migraine pathophysiology through calcitonin gene-related peptide (CGRP) release in the trigeminovascular system. This study aimed to investigate TRPM3 activation and its role in CGRP release, vasodilatory responses, and migraine-relevan
Sociala investeringar i Sverige: Från lovande idé till tyst avveckling
Sociala investeringar lanserades som ett sätt att göra välfärden mer förebyggande, rationell och långsiktigt hållbar. Genom mätbarhet, utvärdering och ekonomiska kalkyler skulle satsningar på människor legitimeras som god politik och god ekonomi. I denna artikel analyseras hur idén om sociala investeringar fick fäste i svenska kommuner – och hur samma logik som bar reformen framåt också bidrog til
Caregiving Quality Across Development and Secure Base Knowledge among Adolescents with a History of Institutional Care
Abstract: Secure base scripts are implicit schemas that guide perceptions, responses, and interactions by encapsulating expectations of support from attachment figures during distress. The current study investigated the impact of early institutional rearing and the causal effects of high-quality foster care following early deprivation on secure base scripts in adolescents who had experienced sever
The Statistical Advantages of Multilevel Analysis of Individual Heterogeneity and Discriminatory Accuracy for Estimating Intersectional Inequalities
Multilevel Analysis of Individual Heterogeneity and Discriminatory Accuracy (MAIHDA) is a multilevel regression approach grounded in intersectionality theory. It examines inequalities across intersections of social identities (e.g., gender, ethnicity, class) and is argued to provide more accurate predictions of intersectional means than conventional methods that estimate group means directly or vi
Infectious Complications During Early Treatment of Childhood Acute Lymphoblastic Leukemia—A Comparison Between the ALLTogether and NOPHO ALL-2008 Protocols
Introduction: Infection remains the most common treatment-related toxicity of childhood ALL, emphasizing the need to identify patients at risk and to tailor treatment strategies accordingly. Aims: The primary aim was to compare infectious toxicity during early treatment for childhood ALL following the ALLTogether and NOPHO ALL-2008 (ALL-2008) protocols, and second, to identify risk factors for inf
Proof-of-concept for a randomized factorial design strategy to build a complex online support program for cancer survivors with psychiatric symptoms : the IN-FACT-0 feasibility trial
Purpose: Internet-delivered cognitive behavioral therapies and lifestyle interventions are promising for reducing psychiatric symptoms in cancer survivors, but little is known about the contribution of specific treatment components to observed effects. A randomized factorial trial could allow for evaluation of the unique contribution of treatment components to overall treatment effects. The IN-FAC
Accelerated Discovery–Fast Access at MAX IV
MAX IV Laboratory, inaugurated in 2016, is a Swedish national synchrotron radiation facility that presently has 16 beamlines in operation. MAX IV consists of three accelerators with different characteristics. The 3 GeV storage ring is the world’s first fourth-generation ring and pioneered the use of the multibend achromat lattice to produce ultrahigh brightness X-rays. MAX IV is the continuation o
Depth and water residence time shape dissolved organic matter removal in constructed wetlands
Climate change has intensified the mobility of dissolved organic matter (DOM) from land into aquatic ecosystems leading to increased brownification and hypoxia. Constructed wetlands (CWs) offer a potential mitigation strategy, yet optimal wetland design and water residence time (WRT) with respect to DOM removal remains underexplored. This study evaluates the effects of shallow and deep CWs on the
