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Mutations in the PTEN gene are associated with a broad spectrum of disorders, including Cowden syndrome (CS), Bannayan-Riley-Ruvalcaba syndrome, Proteus syndrome, and Lhermitte-Duclos disease. In addition, PTEN mutations have been described in a few patients with autism spectrum disorders (ASDs) and macrocephaly. In this study, we screened the PTEN gene for mutations and deletions in 88 patients w

Payments are central for society. Historically, it involved two parties exchanging goods and services for money. Today, payments, with increasing frequency, consist of digital representations of money that are transferred through globally intertwined network. Payments involve many parties such as payers, payment services providers, banks, central banks, telecom operators, mobile handset manufactur

Wilms' tumor gene 1 (WT1) is a zinc finger transcription factor that has been implicated as an oncogene in leukemia and several other malignancies. When investigating possible gene expression network partners of . WT1 in a large acute myeloid leukemia (AML) patient cohort, one of the genes with the highest correlation to . WT1 was quinolinate phosphoribosyltransferase (QPRT), a key enzyme in the .

Exploring autonomic nervous system (ANS) changes during hypnosis is critical for understanding the nature and extent of the hypnotic phenomenon and for identifying the mechanisms underlying the effects of hypnosis in different medical conditions. To assess ANS changes during hypnosis, electrodermal activity and pulse rate variability (PRV) were measured in 121 young adults. Participants either rec

Zeaxanthin, a carotenoid in the xanthophyll cycle, has been suggested to play a role in the protection against photodestruction. We have studied the importance of the parameters involved in zeaxanthin formation by comparing spinach plants grown in low light (100 to 250 mol m-2 s-1) to plants transferred to high light (950 mol m-2 s-1). Different parameters were followed for a total of 11 days. Our

This paper presents a computational study of the combustion process of wood pellets in a small-scale grate fired furnace. The objectives were to obtain detailed information on the combustion characteristics and NO formation in the furnace, and to examine the effect of secondary air on the combustion process. The simulation results were compared with experimental data in terms of flame temperature

Popular Abstract in Swedish Avhandlingen presenterar en experimentell studie av urlakning av betong orsakat av vatten som tränger igenom betongen, eller av diffusion av joner till vatten på uppströmssidan. Urlakningsförloppet och dess effekter modelleras med finita-element-metoden.

DNA chemical and physical networks have been investigated with respect to their stability and swelling, and rheological properties. Chemical networks were prepared by cross-linking DNA with ethylene glycol diglycidyl ether (EGDE), and physical networks by association with cationic polymers. Both types of gels display strong elastic properties and have a shear thinning behaviour. Addition of cation

The wage disparity between women and men stems from the historically unequal valuation of their work. This systemic undervaluation of women's contributions to the labor market has persisted over time, highlighting the ongoing need for regulatory measures to address these inequities and promote greater fairness in pay practices. This study seeks to explore the anticipated impacts of EU Directi

Denna analys undersöker gränsdragningen mellan konstnärlig yttrandefrihet och brott, utifrån exemplet olaga hot i gangsterrap. Analysen har även komparativa inslag utifrån tysk rätt. Genom att presentera tyska rättsfall och den rättsliga diskussion som börjat föras om den tyskspråkiga gangsterrappen ges ytterligare perspektiv och ett större rättsligt sammanhang. Analysen visar att det finns rättsThis analysis examines the right to freedom of artistic expression and its limits within Swedish law, using the example of unlawful threats in gangsta rap. This analysis also includes elements of a comparative method. By examining German law and judicial decisions, the aim is to place Swedish gangsta rap in a broader legal context. The analysis shows legal challenges related to gangsta rap – chal

Våldsutvecklingen i Sverige kan spåras till de förorts- och stadsdelsbaserade gängen och den organiserade brottsligheten i landet anses vara ett av samtidens största problem. För att inte skada grundläggande värden, som demokrati och rättssäkerhet, är det nödvändigt att motverka den organiserade brottsligheten. Oaktat hur brottslig en verksamhet är, saknas det förutsättningar enligt svensk gällandCausing the development of violence in Sweden, organized criminal organizations are considered being one of societies greatest problems. Fundamental values such as democracy and legal security are threatened by the organized crime. Requiring governmental actions to fight organized crime, SOU 2025:2, recommend a change in the Swedish constitution. RF 2 kap. 24§ 2 st. suggests having following formu

The EU’s Common Security and Defence Policy was created to stabilize the EU’s Neighbourhood, fuel the EU’s geopolitical crisis management ambitions, and strengthen European values abroad. In the recent debate, however, it was criticized as ineffective or destabilizing. While specific regions and mission types were previously researched, a comprehensive analysis of all EU crisis management operatio

Uppsatsen utreder huruvida det är förenligt med grundläggande straffrätts-liga principer att beakta gruppens agerande som en förmildrande omständig-het vid fastställandet av straffvärdet. För att undersöka detta granskas de straffrättsliga principerna, begreppet rättssäkerhet och den del av det straffrättsliga påföljdssystemet som rör förmildrande och försvårande omständigheter. Därefter har gäl