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Colombia has been divided by armed conflict for over half a century. While still confronting multiple forms of violence, since the beginning of the peace talks in 2012 public attention in Colombia has shifted to social reconciliation. In June 2014, Colombians re-elected Juan Manuel Santos as president, his campaign having made peace the centre of attention. The peace negotiations in Havana have be

This paper describes a new protein chip method for detection of single-base mismatches and unpaired bases of DNA, using a genetic fusion molecular system Trx-His6-Linker peptide-Strep-tagII-Linker peptide-MutS (THLSLM). The THLSLM coding sequence was constructed by attaching Strep-tag II and mutS gene to pET32a (+) sequentially with insertion of a linker peptide coding sequence before and behind S

Carcinoembryonic antigen (CEA) is not normally produced in significant quantities after birth but is elevated in colorectal cancer. The aim of this review was to define the current role of CEA and how best to investigate patients with elevated CEA levels. A systematic review of CEA was performed, in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.

Layered lithium-rich transition metal oxides are promising cathode candidates for high-energy-density lithium batteries due to the redox contributions from transition metal cations and oxygen anions. However, their practical application is hindered by gradual capacity fading and voltage decay. Although oxygen loss and phase transformation are recognized as primary factors, the structural deteriora

The majority of ectotherms mature at a larger size at lower rearing temperatures. Although this temperature-size rule is well established, a general explanation for this phenomenon has remained elusive. In this article, we address the problem by exploring the proximate and ultimate reasons for why a temperate grasshopper, Chorthippus brunneus, is an exception to the temperature-size rule. Using a

Forests provide grounds for human well-being through direct material, indirect environmental, and immaterial contributions. Here, we analyze the example of Hispaniola to understand reasons for (un)sustainable forest use. We pursue a dynamic comparative case study of the island's two countries from a political ecology perspective. From the literature, we derive a set of socio-economic hypotheses fo

Glycolipid-lectin-driven endocytosis controls the formation of clathrin-independent carriers and the internalization of various cargos such as β1 integrin. Whether this process is regulated in a dynamic manner remained unexplored. Here we demonstrate that, within minutes, the epidermal growth factor triggers the galectin-driven endocytosis of cell-surface glycoproteins, such as integrins, that are

Free-electron lasers are capable of producing high-quality radiation in a wide wavelength range and at very high power and brilliance. To reach improved performance especially regarding coherence, bandwidth and wavelength stability, different seeding techniques are often required. However, a successful implementation of seeding typically demands a very high-quality electron beam, in terms of energ

Post-normal science (PNS) has long advocated the inclusion of stakeholders in scientific processes where there is uncertainty, urgency and high stakes. Increasingly, however, such conditions have become recognised as the norm. Using the theoretical perspective of PNS, we examine the interactions between public objection, unstable coalition politics and uncertain environmental assessment knowledge

The timing and connections between global cooling, marine redox conditions, and biotic turnover are underconstrained for the Late Ordovician. The second most severe mass extinction occurred at the end of the Ordovician period, resulting in ~85% loss of marine species between two extinction pulses. As the only “Big 5” extinction that occurred during icehouse conditions, this interval is an importan

In this qualitative study the author examines the United Nations security council and its possibilities to reform, with help of George Tsebelis theory regarding veto players. The application of the veto player theory gives the ability to measure the policystability, the extent of ability to change policy, when adding more players to a political institution. The study is based on the United Nations

How can an authoritarian leader manage to get reelected for over three decades despite their undemocratic political strategy? This essay aims to explain how this is possible with the theoretical framework dictator’s dilemma, by using a comparative case study between Zimbabwe’s former president Robert Mugabe and Uganda’s president Yoweri Museveni. The motivation of the case selection is their long

This thesis investigates how prominent political leaders construct perceptions of enemies during conflict. Using Schmitt’s Concept of the Political as a starting point, the study explores Julius Caesar’s and George W. Bush’s enemy portrayal of ‘Barbarians’ and ‘Islamic terrorists’. Utilizing a Thematic Analysis, the thesis has explored and compared the narratives of the two leaders during conflict