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Increased expression of Ki-67 in mantle cell lymphoma is associated with de-regulation of several cell cycle regulatory components, as identified by global gene expression analysis

Background and Objectives. Mantle cell lymphoma (MCL) is an aggressive disease. Patients with this malignancy have a median survival of 3 years. To better understand disease progression, which is characterized by increased proliferation, we analyzed the gene expression of MCL with different proliferative indices, as determined by immunohistochemical staining for Ki-67. Furthermore, primary and rel

The genus Fulgensia Mass. & de Not., a diverse group in the Teloschistaceae

The morphology and the anatomy of the 13 species presently included in the genus Fulgensia were surveyed. Caloplaca aurea and C. paulii, two speciesregarded as closely related to Fulgensia by earlier authors, were also included in the study. Fulgensia was found to exhibit a great variation in both morphology and anatomy. The differences in size, shape and septation of the spores, in the anatomy of

Out of the Theoretical Cul-de-sac (Commentary)

A key premise of the heuristics-and-biases program is that heuristics are “quite useful.” Let us now pay more than lip service to this premise, and analyse the environmental structures that make heuristics more or less useful. Let us also strike from the long list of biases those phenomena that are not biases and explore to what degree those that remain are adaptive or can be understood as by-prod