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Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.

We performed fine mapping of 39 established type 2 diabetes (T2D) loci in 27,206 cases and 57,574 controls of European ancestry. We identified 49 distinct association signals at these loci, including five mapping in or near KCNQ1. 'Credible sets' of the variants most likely to drive each distinct signal mapped predominantly to noncoding sequence, implying that association with T2D is mediated thro

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.

The QT interval, an electrocardiographic measure reflecting myocardial repolarization, is a heritable trait. QT prolongation is a risk factor for ventricular arrhythmias and sudden cardiac death (SCD) and could indicate the presence of the potentially lethal mendelian long-QT syndrome (LQTS). Using a genome-wide association and replication study in up to 100,000 individuals, we identified 35 commo

Diffractive electroproduction of rho and phi mesons at HERA

Diffractive electroproduction of rho and phi mesons is measured at HERA with the H1 detector in the elastic and proton dissociative channels. The data correspond to an integrated luminosity of 51 pb(-1). About 10500 rho and 2000 phi events are analysed in the kinematic range of squared photon virtuality 2.5 <= Q(2) <= 60 GeV2, photon-proton centre of mass energy 35 <= W <= 180 GeV and squared four

Rapport

Rapport Stärkande samtal – fyra fallstudier av invandrarfamiljers läkarbesök i barndiabetesvården Anna W Gustafsson           © författaren, 2014 ISSN 0281-5427 ISBN 978-91-87833-02-1 (tryck) ISBN 978-91-87833-03-8 (pdf) Tryck: Media-Tryck, Lunds universitet, 2014 Nordlund är en småskriftsserie, grundad 1982, som har getts ut av Institutionen för nordiska språk, Lunds universitet, från 2006 av Nor

https://projekt.ht.lu.se/fileadmin/user_upload/project/nordlund/Nordlund/Nordlund_33_Gustafsson.pdf - 2026-05-04

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Master’s Dissertation Engineering Acoustics LOVE KLASSON Report TV BA -5054 LO V E K LA SSO N STU D IE O M EN FÖ R B Ä TTR A D TA LU PPFA TTN IN G I K LA SSR U M M ED A V SEEN D E PÅ B A R N M ED C O C H LEA IM PLA N TA T STUDIE OM EN FÖRBÄTTRAD TALUPPFATTNING I KLASSRUM MED AVSEENDE PÅ BARN MED COCHLEAIMPLANTAT TVBA-5054HO.indd 1TVBA-5054HO.indd 1 2018-11-07 18:12:112018-11-07 18:12:11 DEPARTMENT

https://www.akustik.lth.se/fileadmin/tekniskakustik/publications/tvba5000/webTVBA5054.pdf - 2026-05-04

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MIDLANDS STATE UNIVERSITY LAW REVIEW SPECIAL EDITION 2025 First published October 2014 Midlands State University Law Review June 2025 Special Issue Official citation: (2025) Midlands State University Law Review Special Issue Copyright © 2025 Midlands State University This is a limited, non-commercial print run authorised by Raoul Wallenberg Institute of Human Rights and Humanitarian Law for traini

https://rwi.lu.se/wp-content/uploads/2025/10/MSULR-Special-Issue-2025-PR.pdf - 2026-05-04

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Evaluation Report of The Raoul Wallenberg Institute’s Kenya Programme 2015-2019 Prepared by: Debra Long - Human Rights Implementation Centre, University of Bristol, UK Rachel Murray - Human Rights Implementation Centre, University of Bristol, UK Hindpal Singh Bhui, HM Inspectorate of Prisons, UK and University of Oxford, UK 6 January 2020 2 Table of Contents Executive Summary .....................

https://rwi.lu.se/app/uploads/2020/06/final-report-evaluation-of-the-rwi-kenya-programe-2015-2019.pdf - 2026-05-04

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untitled I - P L A N E F R A C T U R E O F P A P E R R e p o r t T V S M - 1 0 0 8 J O H A N T R Y D I N G IN-PLANE FRACTURE OF PAPER JOHAN TRYDING LUND UNIVERSITY ⏐⏐⏐⏐⏐ LUND INSTITUTE OF TECHNOLOGY Division of Structural Mechanics ⏐⏐⏐⏐⏐ Sweden 1996 ⏐ ⏐ ⏐ ⏐ ⏐ Report TVSM-1008 Detta är en tom sida! LUND UNIVERSITY LUND INSTITUTE OF TECHNOLOGY Division of Structural Mechanics Sweden Report TVSM COD

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm1000/web1008.pdf - 2026-05-04

Handledning för inrättande och avvecklingav program och huvudområden vid LTH

Handledning för inrättande och avvecklingav program och huvudområden vid LTH Handledning för inrättande och avveckling av program och huvudområden vid LTH Avdelningen för Kvalitetsstöd Dnr U 2024/61 2024 Sida 1 av 52 Innehåll Inrättande och avveckling av program och huvudområden ..................... 4 1 Inrättande av program .......................................................................

https://www.lth.se/fileadmin/lth/anstallda/kvalitet/Inraettandeproevning/Handledning_foer_inraettande_av_program_reviderad_2024.pdf - 2026-05-04

Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331288 participants

Background Diabetes has been defined on the basis of different biomarkers, including fasting plasma glucose (FPG), 2-h plasma glucose in an oral glucose tolerance test (2hOGTT), and HbA(1c). We assessed the effect of different diagnostic definitions on both the population prevalence of diabetes and the classification of previously undiagnosed individuals as having diabetes versus not having diabet

Beyond the neutron drip line: The unbound oxygen isotopes O-25 and O-26

The very neutron-rich oxygen isotopes O-25 and O-26 are investigated experimentally and theoretically. The unbound states are populated in an experiment performed at the R3B-LAND setup at GSI via proton-knockout reactions from F-26 and F-27 at relativistic energies around 442 and 414 MeV/nucleon, respectively. From the kinematically complete measurement of the decay into O-24 plus one or two neutr

Variants in MTNR1B influence fasting glucose levels

To identify previously unknown genetic loci associated with fasting glucose concentrations, we examined the leading association signals in ten genome-wide association scans involving a total of 36,610 individuals of European descent. Variants in the gene encoding melatonin receptor 1B (MTNR1B) were consistently associated with fasting glucose across all ten studies. The strongest signal was observ

Landscape of somatic mutations in 560 breast cancer whole-genome sequences

We analysed whole-genome sequences of 560 breast cancers to advance understanding of the driver mutations conferring clonal advantage and the mutational processes generating somatic mutations. We found that 93 protein-coding cancer genes carried probable driver mutations. Some non-coding regions exhibited high mutation frequencies, but most have distinctive structural features probably causing ele

Systematic investigation of projectile fragmentation using beams of unstable B and C isotopes

Background: Models describing nuclear fragmentation and fragmentation fission deliver important input for planning nuclear physics experiments and future radioactive ion beam facilities. These models are usually benchmarked against data from stable beam experiments. In the future, two-step fragmentation reactions with exotic nuclei as stepping stones are a promising tool for reaching the most neut

A reference panel of 64,976 haplotypes for genotype imputation

We describe a reference panel of 64,976 human haplotypes at 39,235,157 SNPs constructed using whole-genome sequence data from 20 studies of predominantly European ancestry. Using this resource leads to accurate genotype imputation at minor allele frequencies as low as 0.1% and a large increase in the number of SNPs tested in association studies, and it can help to discover and refine causal loci.

Coulomb dissociation of N 20,21

Neutron-rich light nuclei and their reactions play an important role in the creation of chemical elements. Here, data from a Coulomb dissociation experiment on N20,21 are reported. Relativistic N20,21 ions impinged on a lead target and the Coulomb dissociation cross section was determined in a kinematically complete experiment. Using the detailed balance theorem, the N19(n,γ)N20 and N20(n,γ)N21 ex

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Supervising Interdisciplinary Theses TEACHING FOR SUSTAINABILITY | 12 OCTOBER 2023 Provide the protected time and space to reflect on your own approach to supervising interdisciplinary thesis, inspired by the content and discussions during the seminar Invitation • Becoming present – Calming breaths – Check-in with your body – Set your intention – Something else – Nothing else Agenda • Introduction

https://www.ahu.lu.se/fileadmin/user_upload/ahu/Images/Teaching_for_Sustainability/Seminars/SLIDES_Supervising_Interdisciplinary_Thesis_12Oct2023.pdf - 2026-05-04

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Exercise for Optimal control – Week 3 Choose 1.5 problems to solve. Disclaimer This is not a complete solution manual. For some of the exercises, we provide only partial answers, especially those involving numerical problems. If one is willing to use the solution manual, one should judge whether the solutions are correct or wrong by him/herself. Exercise 1. Consider a harmonic oscillator ẍ + x =

https://www.control.lth.se/fileadmin/control/Education/DoctorateProgram/Optimal_Control/2023/ex3-sol.pdf - 2026-05-04