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Parkinson´s disease (PD) is one of the most common neurological diseases with both motor and non-motor symptoms that can be perceived as difficult to control despite medical treatment. This leads to several consequences in everyday life for example difficulties in activities of daily living (ADL), sometimes already at diagnosis. Therefore, rehabilitation is important to manage the consequences of
Innovation has received widespread attention in research and in the business world because it plays a crucial role in organization survival and longevity. This especially rings true in the retail industry, as opportunities and challenges confront retailers due to the ongoing disruption of the industry. As retailers face increasing pressure to make innovation a strategic priority, and as major reta
Background/Purpose: Rheumatoid arthritis (RA) is associated with an increased risk of cardiovascular disease (CVD). Systemic inflammation, driven by cytokines such as TNF, IL-6 and IL-17A, has been implicated as a contributing factor to CVD development in RA. The objective of this study was to investigate the impact of 92 inflammatory proteins on the risk of CVD events in patients with early RA.Me
BACKGROUND: Epidemiological studies have demonstrated an association between the degree of food processing in our diet and the risk of various chronic diseases. Much of this evidence is based on the international Nova classification system, which classifies food into four groups based on the type of processing: (1) Unprocessed and minimally processed foods, (2) Processed culinary ingredients, (3)
Solar access describes the amount and distribution of sunlight in living environments. Access to sunlight is crucial for the health and sustainability of cities. It is vital for people and vegetation, and for energy production and conservation. The amount of sunlight entering the city space is restricted by the urban layout, as buildings obstruct solar access by shading each other and the surround
Deciphering the metamorphic evolution of the roots of mountain belts is essential for understanding deep tectonic processes involved in mountain building. The Sveconorwegian orogen in southwestern Scandinavia, formed during the Rodinia assembly in the transition between the Mesoproterozoic and Neoproterozoic Eras, has been exhumed and provides access to interior deep structural levels of the ancie
Background: With a trend toward de-escalation of axillary surgery in breast cancer, prediction models incorporating imaging modalities can help reassess the need for surgical axillary staging. Although mammography is routinely performed for breast cancer imaging, its potential in nodal staging remains underutilized. This study aims to employ advancements in deep learning (DL) to comprehensively ev
Stödgrupper för barn som växer upp i familjer med psykisk ohälsa, skadligt bruk/beroende eller våld är en insats som erbjuds av socialtjänsten i många kommuner. Trots att stödgrupper ges på frivilliga grunder utan biståndsprövning, dvs ”lätt tillgängligt” (Prop.2024/25:89), är rekryteringen av barn en utmaning. Denna licentiatuppsats fördjupar kunskapen om de förhållanden och överväganden som påve
Proposing “sustainable meetings”: convention bureaus marketing of destinations as ethicalIn the wake of a crisis and restrictions on physical interactions, the importance of meetings is emphasized more than ever. The meetings industry has gone from unprecedented down-sizing to higher booking rates than ever, and attracting meetings is an important part of municipalities place brandingstrategies. A
The normal-like molecular subtype of breast cancer has not been well characterized and is currently not included in the clinically approved PAM50 molecular subtype classification. Tumors classified as normallike display high expression of basal epithelial genes and low expression of luminal epithelial genes, but also high expression of genes expressed by non-epithelial cell types including adipocy
Introduction.Kraft black liquor is a side-stream produced during the kraft pulping process containing lignin, hemicelluloses and cooking chemicals. The stream is usually evaporated and burned in the recovery boiler to recover the cooking chemicals and generate energy. The mill is, however, often/sometimes limited by recovery boiler capacity, and removing some of the lignin from kraft black liquor
Fjärrvärme och fjärrkyla är ändamålsenliga system för distribution av värme och kyla i tätbebyggda områden. Dessa system är viktiga vid planeringen av framtida energieffektiva system på grund av deras höga potential för att integrera förnybara energikällor. Systemen spelar också en viktig roll i samhällets energiförsörjningssäkerhet, vilket gör dem till ett tvärvetenskapligt forskningsområde. Den District heating and cooling are efficient systems for distributing heat and cold in urban areas. They are a key solution for planning future urban energy-efficient systems due to their high potential for integrating renewable energy sources. The systems also play an important role in community resilience, which makes them a multidisciplinary research topic. The continuous development of these sys
In most cases, antiretroviral therapy (ART) results in undetectable plasma HIV viral load (VL). Still, up to 25% of ART recipients may have detectable low-level viremia (LLV) of different amplitude and persistence. This thesis explores the impact of LLV during ART on virologic and clinical outcomes. Paper I–III are retrospective analyses based on InfCare HIV, a national quality register for people
This study critically evaluates David Harvey’s model of urban land rent and its centrality in his explanation of the material forces that underlie and limit urban land policies, strategies, planning decisions, and investment choices. Harvey emphasizes structural forces of capital in relating economic urbanization processes to uneven patterns of capitalist development, recurrent economic crises of
The purpose of this thesis is to add an astronomical component to the history and evolution of Earth by reconstructing the micrometeorite flux to Earth at different time intervals during the Phanerozoic Eon, using sediment-dispersed extraterrestrial spinel group minerals as a proxy. Chromite and chrome spinel are common refractory members of the spinel group, occurring in both extraterrestrial and
BACKGROUND: Exercise and education is recommended as first-line treatment by evidence-based, international guidelines for low back pain (LBP). Despite consensus regarding the treatment, there is a gap between guidelines and what is offered to patients. Digital LBP treatments are an emerging way of delivering first-line treatment.OBJECTIVE: The aim of this study is to evaluate outcomes after partic
The chemical industry is primarily dependent on fossil oil and gas as raw materials. With increasing demands on reducing the greenhouse gas emissions and carbon footprint attributed to fossil based production, the industry looks for alternative renewable cleaner resources to secure the supplies for future chemical and material products. The current trend in the shift to bio-based economy aims at u
Importance Active perinatal care increases survival of extremely preterm infants; however, improved survival might be associated with increased disability among survivors. Objective To determine neurodevelopmental outcome in extremely preterm children at 2.5 years (corrected age). Design, Setting, and Participants Population-based prospective cohort of consecutive extremely preterm infants born be
