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Type 2 diabetic patients usually exhibit an abnormal lipid profile. One such lipid that is constantly elevated in T2D is cholesterol. At the cellular level, cholesterol aids in tight packing of sphingolipids in certain regions of the plasma membrane and these specialized regions are termed ‘membrane rafts’, which act as signalling hubs. In pancreatic beta cells, these structures have been found to
The objectives of the work presented in this thesis have been to develop molecular methods for (i) detection of Clostridium botulinum in food and clinical samples, and (ii) monitoring the expression of the neurotoxin gene, cnt, during different growth phases and under different growth conditions. For the diagnosis of botulism, a real-time PCR-based method including an internal amplification contr
Changing Landscapes and Persistent Places is a study of the cultural landscape on the Bjäre peninsula in northwest Skåne. The many Bronze Age remains that give the landscape its distinctive character are the starting point for an attempt to increase our understanding of the historical depth of today’s landscape. The two perspectives of “landscape” and “places” carry the discussion forward, almost
In all works on medieval Iceland, we meet the same narrative of the conversion of Iceland to Christianity, which is supposed to have taken place in the year 999 or 1000 AD. But how does this narrative stand the trial of source criticism? Radical source criticism was introduced in Nordic historiography when Lauritz Weibull published his Critical Studies in Nordic History Around the Year 1000 in 191
Stratagems adopted by democratic leaders to try to insinuate, or anchor, a preferred course of action into the larger collective will have a variety of repercussions. Beyond the apparent success of the venture itself, the long-term integrity of the democratic fabric may be at stake if simmering rancour and discontent is left unheeded. These questions would seem particularly pertinent when studyi
This thesis presents the results of an investigation into BIM implementation prerequisites emerging as a set of procedural supporting mechanisms that may enable design, construction and operating (DCO) organisations to advance their deployment of Building Information Modelling (BIM) technology, and improve construction project outcomes. Today, BIM is centre-stage within the construction sector the
This dissertation considers two different aspects of health economics; (i) stated preference methods and (ii) empirical analyses of equity. The first essay deals with the issue of the choice of econometric models when analysing data from a closed-ended contingent valuation survey in health economics. The features of provision, either compulsory or voluntary, and the fact that certain individuals m
The first chapter develops a theoretical model of marriage and divorce. The model has two periods and assumes Pareto efficient time allocations. There is a risk of divorce in the second period, which is modeled as exogenously given. The second chapter utilizes the model developed in the previous chapter to analyze the equality between married men and women. Equality is defined as the spouses' rel
This thesis consists of three empirical studies on asset-prices in international financial markets. The purpose is three-fold. First, to evaluate whether good predictions of economic variables may be obtained by pooling information from a broad group of financial variables. Second, to formulate asset-pricing models from seven established stock markets. Third, to evaluate the asset-pricing models i
Coronary artery diseases (CAD) are main causes of morbidity and hospitalisation in western countries and CAD patients are at considerable risk of suffering further cardiac events. The development and evaluation of secondary prevention programmes therefore an important task. This thesis includes investigations on CAD patients admitted to a secondary prevention programme at Malmö University Hospital
I have briefly outlined different levels of scale in the discussion of centre–periphery, from a local to a more global perspective. I have tried to show that the concepts of centre and periphery cannot be applied without qualification. Different realities are concealed behind them. The common factor is nevertheless that they signal some kind of contacts, in the form of giving and taking, of power,
In this report a generic model for the capture and assessment of end-user requirements and needs, the CREDIT carpenter model, has been developed. The main determinants of the model is the need for the project organisation (including the facilities management organisation) to ensure a thorough understanding of the end-user requirements and needs as well as an assessment through out the project proc
During south Scandinavian Late Bronze Age, c. 900-500 BC, a new tool was invented. It consisted of a wooden shaft and a knife blade made out of flint. One singel of this tool still exists today. It was found in a Danish bog in late 19th century. But there are many of the knife blades of flint; in museum collections or in flint assemblages from archaeological excavations. Archaeologists call them l
Plants like all other eukaryotic organisms carry most of their DNA in the nucleus. In addition, plants also have both chloroplasts and mitochondria that contain their own genetic material. The genomes in chloroplasts and mitochondria control certain vital processes, but most often the organelles act under strict nuclear control. Usually the nuclear and organellar genomes live in "harmony", promoti
The EU governance of food safety and GM food and feed has gone through significant changes since the BSE crisis and food scares during the 1990s. This work focuses on one particular new feature; the role of stakeholders representing the food chain: biotech associations, farmer organizations, food and feed processors, consumer organizations and environmental NGOs. These stakeholders are not merely
