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Background & Aims: It is unclear to what extent lifestyle and genetic factors affect the incidence of chronic liver disease (CLD) in the general population and if lifestyle affects CLD independently of underlying cardiometabolic perturbations and genetic predisposition. Methods: We examined 27,991 men and women aged 44-73 years from the Malmö Diet and Cancer Study recruited between 1991-1996 a

Background/ Objectives: Research into ANCA-associated vasculitis (AAV) is hampered by the rarity of the disease and thesubsequent small sample sizes of observational cohorts. This is further aggravated by the observational cohorts being containedin fragmented data pools and lacking standardisation to allow for interoperability. FAIRVASC is a Europe-wide research project,which has developed an infr

Bioenergy plays a major role in the renewable energy supply and is projected to be an important part of the path towards a decarbonised society. Over the past decade, increasing attention has been given to agricultural bioenergy to act as a multifunctional climate mitigation strategy. Energy crops may mitigate climate change while simultaneously contributing to reducing the negative environmental

BACKGROUND:Postural orthostatic tachycardia syndrome (POTS) is a frequently diagnosed cardiovascular disorder after COVID-19 infection. POTS is characterized by the presence of excessive sinus tachycardia on standing without a fall in blood pressure (BP). We investigated the BP profile using 24-hour ambulatory BP monitoring in patients with new-onset POTS after COVID-19 compared with prepandemic p

Extraction of vitamin D, including its hydroxylated and esterified metabolites, from soft tissues such as the liver is challenging due to the lipophilic character of matrix and analytes that are expected in very low concentration levels. In this study, we aimed at the optimization of two-step extraction using solid–liquid extraction as the first step, followed by solid-phase extraction. Various so

BACKGROUND: Parkinson's disease (PD) is a chronic neurodegenerative disorder with limited knowledge about the normal function and effects of non-pharmacological therapies on the hypothalamic-pituitary-adrenal (HPA) axis. The aim of the study was to analyse the basal diurnal and total secretion of salivary cortisol in short- and long-term aspects of tactile massage (TM).DESIGN: Prospective, Control

Background: Diabetes in pregnancy is associated with increased risk of long-term metabolic disease in the offspring, potentially mediated by in utero epigenetic variation. Previously, we identified multiple differentially methylated single CpG sites in offspring of women with gestational diabetes mellitus (GDM), but whether stretches of differentially methylated regions (DMRs) can also be identifi

Informed by queer life practices, theories, and affinities, this documented artistic research project (doctoral thesis) draws from new materialist and post-humanist discourse in order to reconsider what role visual media play in the historical need to separate the human and the environmental. It asks, how do we challenge prevailing perceptions of film and photography as inexorably linked to ideas

Disaster-induced and conflict-induced forced displacements areamong the biggest humanitarian and development challenges of the countriesaround the world in the 21st century. The increasing rate of the forced displacementputs significant pressure on the built environment which popularly includes thechallenges associated with delivering the essential goods and services, providingadequate and appropr

Background: Elevated cerebrospinal fluid (CSF) concentrations of total tau (T-tau) and phosphorylated tau at Thr181 (P-tau181) protein are typical of Alzheimer’s disease (AD). However, the T-tau assay measures only the mid-region of the protein, while tau in CSF is instead composed of a series of fragments. One fragment species in particular, N-224, shows increased levels in AD compared to control

Colorectal cancer (CRC) is one of the most common forms of cancer. The cause of CRC is multifactorial, and lifestyle factors are thought to be a major contributor to the development of CRC. It can be hypothesised that the association between food intake and the risk of developing CRC depends not only on the food consumed, but what it is consumed in combination with. The associations between food a

Evaluations of the other culture is a strong force, not only in cultural dialogue but, consequently, in a culture’s formation of itself. Cultures are formed, as it were, in encounters that include domination, conflict, and dismissal as much as appreciation and smooth exchange. In this paper, the construction of cultural identity is discussed, in a study of a Scandinavian Theme Park proposal that w

Objective. The major aim was to study the relation between habitual dietary intake and glucose tolerance, insulin sensitivity and insulin secretion in postmenopausal women. Dietary intake was also compared between women with normal (NGT) or impaired glucose tolerance (IGT). Design. Habitual dietary intake was studied using a modified diet history method, from which the energy, carbohydrate, fat an

Species-based ecological indices, such as Ellenberg indicators, reflect plant habitat preferences and can be used to describe local environment conditions. One disadvantage of using vegetation data as a substitute for environmental data is the fact that extensive floristic sampling can usually only be carried out at a plot scale within limited geographical areas. Remotely sensed data have the pote

Clinical education is a significant part of nursing education on all levels of education. A lot of effort is made by educational providers to prepare the students for their clinical placement (Levett-Jones et al., 2015). At best, this is a shared enterprise, involving representatives from the profession in creating a useful clinical placement for the students. However, the strain on clinical nurse

Objectives: A single nucleotide polymorphism in the NCF1 gene (NCF1-339, rs201802880), encoding NADPH oxidase type II subunit NCF1/p47phox, reducing production of reactive oxygen species (ROS) is strongly associated with the development of systemic lupus erythematosus (SLE). This study aimed at characterising NCF1-339 effects on neutrophil extracellular trap (NET) formation, type I interferon acti

Importance: Breast cancer screening guidelines acknowledge the need for earlier screening for women at increased risk but provide limited guidance for women with a family history of breast cancer. A risk-adapted starting age of screening for relatives of patients with breast cancer may help supplement current screening guidelines. Objective: To identify the risk-adapted starting age of breast canc