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Objective: To explore how cancer survivors have experienced their contacts with primary care after being diagnosed with cancer, focusing on the integration between cancer specialist and primary care, and participants’ views on what could make primary care services better at catering to the needs of cancer survivors. Design: A qualitative study in which data was collected through semi-structured di

Avhandlingen är en studie av hur stöd och service organiseras kring fyra barn med funktionshinder och deras familjer. I denna service är normalt flera olika formella organisationer involverade, som barnhabilitering, förskola/skola/särskola, hjälpmedelscentral, assistentorganisationer, sjukvård m fl. Dessutom kan barnets och familjens situation vara komplicerad på många sätt. Själva funktionshindre

Boreal forests and peatlands store over 30% of the global terrestrial carbon in their vegetation and soil. but changing climate can compromise the current carbon stock. Rising air temperatures, changing precipitation patterns and increased risk of natural disturbances can impact the ability of the boreal ecosystems to absorb and store carbon, reducing their effectiveness as carbon sinks. Reliable

De senaste årens fokus på säkerhetsrisker i samhället har gett upphov till olika former av polisarbete, såsom gränsöverskridande och underrättelsebaserat polisarbete. Den här studien uppmärksammar ett samverkansprojekt mellan gränsmyndigheter i Östersjöområdet som pågick mellan 2014 och 2015. Projektet fick namnet Turnstone och involverade underrättelsepoliser, gränspoliser och kustbevakare från SThe risks and insecurities emphasised in contemporary societies have given rise to diverse forms of policing, such as transnational and intelligence-based police collaborations. This dissertation focuses on a border police collaboration project, called Turnstone, that took place between 2014 and 2015, aiming to address issues related to irregular migration and cross border crimes in the Baltic Sea

Visuals like photographs and videos produced and circulated by lay people in social media serve as significant mediators in crisis communication. Such visuals are crucial for the way contemporary crisis events are defined and perceived in public (Mortensen, 2015; Coombs, 2007). This type of eyewitness footage is a growing visual genre of crisis communication. Yet, previous studies tend to neglect

Childless men are reported to have a higher risk of cardiovascular disease (CVD) and mortality. Information on inherited genetic risk for CVD has improved the predictive models. Presuming that childlessness is a proxy of infertility we aimed to investigate if childless men inherit more often genetic traits for CVD and if combining genetic and parenthood information improves predictive models for C

OBJECTIVE: Access to effective treatments for adolescents with depression needs to improve. Few studies have evaluated behavioural activation (BA) for adolescent depression, and none remotely delivered BA. This study explored the feasibility and acceptability of therapist-guided and self-guided internet-delivered BA (I-BA) in preparation for a future randomised controlled trial (RCT). DESIGN: A si

IMPORTANCE: A 50% reduction of glaucoma-related blindness has previously been demonstrated in a population that was screened for open-angle glaucoma. Ongoing screening trials of high-risk populations and forthcoming low-cost screening methods suggest that such screening may become more common in the future. One would then need to estimate a key component of the natural history of chronic disease,

To accommodate surplus energy, the adipose tissue expands by increasing adipocyte size (hypertrophy) and number (hyperplasia). The presence of hypertrophic adipocytes is a key characteristic of adipose tissue dysfunction. High-fat diet (HFD) fed C57BL/6J mice are a commonly used model to study obesity and obesity-related complications. In the present study, we have characterized adipose plasticity

Objective: To determine the relation between concentrations of prostate specific antigen at age 60 and subsequent diagnosis of clinically relevant prostate cancer in an unscreened population to evaluate whether screening for prostate cancer and chemoprevention could be stratified by risk. Design: Case-control study with 1:3 matching nested within a highly representative population based cohort stu

RATIONALE: Vascular calcification is a prominent feature of late-stage diabetes, renal and cardiovascular disease (CVD), and has been linked to adverse events. Recent studies in patients reported that plasma levels of osteomodulin (OMD), a proteoglycan involved in bone mineralisation, associate with diabetes and CVD. We hypothesised that OMD could be implicated in these diseases via vascular calci

Avhandlingen närmar sig frågan om hur journalistiska praktiker underlättar konstruktionen av kändisstatus. Teoretiskt uppfattas kändisskap som en särskilt flytande form av social status baserat på medierad uppmärksamhet och engagemang. Journalistik studeras som en invitation att dela upplevelser, organiserade utifrån narrativa strukturer. De empiriska fallen som studeras i avhandlingen är två mångThe thesis approaches the research question of how journalistic practices facilitate the construction of celebrity status. Theoretically, celebrity is conceptualised as a particularly fluid form of social status based on mediatized attention and engagement. Journalism is studied as an invitation to shareexperiences, organised through media logics and narrative structures. The empirical cases studi

Parkinson’s disease (PD) and cardiovascular disease share many important risk factors, but some associations differ. However, there are no studies that have compared their shared and specific risk factors. The present study aimed to compare risk factors for PD, coronary events, or ischemic stroke. We prospectively analyzed data from 26,210 participants with lifestyle factors aged 45–73 years enrol

Background: The introduction of next-generation sequencing into the diagnosis of neuromuscular disorders has resulted in an increased number of newly identified RYR1 variants. The hypothesis was that there is an increased referral of patients to malignant hyperthermia units without a personal/family history of adverse anesthetic events suspected to be malignant hyperthermia. This retrospective mul

It is widely recognised that society is consuming at levels and in ways that are unsustainable. Sustainable business models, broadly defined as those that consider economic, ecological and social value, hold promise for shifting consumption patterns. By facilitating activities such as rental and reuse, including second-hand, repair, refurbishment, and upcycling, they can help to provide more susta

Kollektivtrafikplanering är en balansakt. Å ena sidan är det viktigt att satsa där det finns potential för många resor. Då krävs en koncentration av resurserna till stråk och noder med stort befolkningsunderlag. Å andra sidan är det också angeläget att skapa en rättvis fördelning av den offentliga service som utgörs av kollektivtrafiksystemet, så att även människor i mer glesbefolkade områden ges This thesis addresses the demand for more knowledge regarding regional public transport (between urban areas or to and from rural areas). More specifically, the aim is to develop a better understanding of the effects of different service planning decisions in terms of different trade-offs and their impacts on the overarching objectives of public transport provision. The studied trade-offs concern,

Background: The autonomic nervous system (ANS) is known as a potent modulator of the initiation and perpetuation of atrial fibrillation (AF), hence information about ANS activity during AF may improve treatment strategy. Respiratory induced ANS variation in the f-waves of the ECG may provide such information. Objective: This paper proposes a novel approach for improved estimation of such respira

Aims: Repeated risk assessments and treatment patterns over long time are sparsely studied in chronic thromboembolic pulmonary hypertension (CTEPH); thus, we aimed to investigate changes in risk status and treatment patterns in incident patients with CTEPH over a 5 year period. Methods and results: Descriptive and explorative study including 311 patients diagnosed with CTEPH 2008–2019 from the Swe

Extraction of vitamin D, including its hydroxylated and esterified metabolites, from soft tissues such as the liver is challenging due to the lipophilic character of matrix and analytes that are expected in very low concentration levels. In this study, we aimed at the optimization of two-step extraction using solid–liquid extraction as the first step, followed by solid-phase extraction. Various so