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OBJECTIVES: To investigate whether the interleukin-1 receptor antagonist (Il-1ra) and interleukin-1beta (Il-1beta) can be detected in human carotid artery tissue, and whether their presence is related to evidence of Chlamydia pneumoniae infection, risk factors for atherosclerosis, and clinical data. SETTING: Departments of Vascular Diseases and Surgical Pathophysiology, University Hospital, Malmö,

Objective: The aim of the present study was to investigate the perceived anxiety, depression, sleeping habits, and participation in social activities in relation to psychotropic drug use among elderly in assisted-living facilities and to identify factors of importance for the use of these drugs. Method: The study had a cross-sectional design and included 93 residents living in old-age homes or in

Purpose: We investigated the distribution of cannabinoid receptor subtypes 1 and 2 in the detrusor of different species and studied the effects of cannabinoid receptor 1 and 2 agonists on bladder function. Materials and Methods: Cannabinoid receptor 1 and 2 expression was studied with Western blot and immunohistochemistry in rat, monkey and human detrusors. Co-staining was done for markers of sens

This intermediate report presents some of the important findings of the research work carried out during the first three years of the CHRISGAS project. The report is aimed at a broad technical-oriented audience such as: engineers with a general interest in the state-of-the-art and new developments in the biomass-to automotive fuel sector, and/or to teachers/lecturers/students in technical subjects

Lactic acid exists as two optical isomers, D- and L-lactic acid. For the production of biodegradable poly-lactic acid an optically pure product is desirable, but a racemate of known and constant ratio can also be used. Lactic acid can be produced either synthetically or fermentatively. Fermentative production has some advantages: by choosing a lactic acid bacterium producing only one of the isomer

The research project "Exclusive metalworking in rural settings" was instigated in 2013 with funding from Berit Wallenbergs foundation. The projects objective is to survey sites housing remains of multimetal craftsmanship of the late Iron Age and medieval periods outside urban contexts. This article aims to contextualize preliminary results from the project by evaluating its chosen source material

The bio-economy has been put forward as a strategy to increase economic growth without this leading to increased emissions of greenhouse gases. A key concept behind the bio-economy is the increased use of biomass for applications such as the production of bio-based chemicals and materials but also an increased importance for biotechnology and biorefinery systems in the production of these products

This chapter provides a synthesis of three earlier published studies (Garmy et al. 2012a; Garmy et al. 2012b; Garmy et al. 2013) (survey I) as well as previously unpublished results from a survey conducted in 2013 among students aged 16 (survey II). Objective: The aim was to investigate the effects of sleep, television use and texting and computer habits on overweight, enjoyment of school and fee

The main ambition of companies is to deliver products (or services) to customers successfully in order to remain competitive. This requires an efficient and effective product development process, as well as cost reductions and higher service levels through improved logistics performance in the supply chain. Traditionally, these two areas, i.e. product development and logistics, have been treated s

OBJECTIVE: The brain derived neurotrophic factor (BDNF) locus has been implicated in psychiatric and substance related disorders. Recent genome-wide association studies (GWAS) have shown strong associations between single nucleotide polymorphisms in BDNF, smoking behaviour and high body mass index (BMI). Our aim was to test whether genetic BDNF variation alters the risk of smoking related morbidit

Although methylenetetrahydrofolate reductase, a folate enzyme gene, has been associated with idiopathic male infertility, few studies have examined other folate-related metabolites and genes. We investigated whether idiopathic male infertility is associated with variants in folate, vitamin B-12 (B12) and total homocysteine (tHcy)-related genes and measured these metabolites in blood. We conducted

GLP-1 receptor agonists may provide an alternative to prandial insulin for advancing basal insulin therapy. Harmony 6 was a randomized, open-label, active-controlled trial testing once-weekly albiglutide vs thrice-daily prandial insulin lispro as an add-on to titrated once-daily insulin glargine.RESEARCH DESIGN AND METHODS: Patients taking basal insulin (with or without oral agents) with HbA1c 7-1

Genome wide association studies (GWAS) for fasting glucose (FG) and insulin (FI) have identified common variant signals which explain 4.8% and 1.2% of trait variance, respectively. It is hypothesized that low-frequency and rare variants could contribute substantially to unexplained genetic variance. To test this, we analyzed exome-array data from up to 33,231 non-diabetic individuals of European a

Phenological shifts linked to global warming reflect the ability of organisms to track changing climatic conditions. However, different organisms track global warming differently and there is an increasing interest in the link between phenological traits and plant abundance and distribution. Long-term data sets are often used to estimate phenological traits to climate change, but so far little has