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Analysis of fire barriers with respect to fires with combustible gases and liquids

Fires including flammable gases and/or liquids differ from typical residential fires where the fuel is mainly composed of solid combustibles. The traditional ISO 834 curve was established to represent the timetemperature curve for a fully developed fire. However for combustible gases the type of thermal exposure might be substantially different and therefore other curves have been developed such a

Variability of BVOC Emissions from Commercially Used Willow (Salix spp.) Varieties

Willow (Salix spp.) trees are commonly used in short rotation coppices (SRC) to produce renewable energy. However, these plants are also known to emit high concentrations of biogenic volatile organic compounds (BVOCs), which have a large influence on air quality. Many different clones of commercially used Salix varieties exist today, but only a few studies have focused on BVOC emissions from these

The genetic landscape of renal complications in type 1 diabetes

Diabetes is the leading cause of ESRD. Despite evidence for a substantial heritability of diabetic kidney disease, efforts to identify genetic susceptibility variants have had limited success. We extended previous efforts in three dimensions, examining a more comprehensive set of genetic variants in larger numbers of subjects with type 1 diabetes characterized for a wider range of cross-sectional

Past and Future Embedded in the Present : A Cultural History of a Local Shopping Street

Most of the literature accumulated around retail change derive a linear, progressive understanding, typically coined with the term “retail evolution”. Once it is formulated as such, a need for adopting a historical perspective to study present becomes superfluous, because the past is understood as something that is left behind, something incapable of making an impact on the present. In this resear

Managing the Chemical Risks of Consumer Goods: Two Roles and Challenges of Civil Society Organisations

To manage risks in Western society is increasingly seen as a process of including the public in different deliberative and/or participatory projects. This is sometimes done via civil society organisations (CSOs) that also have a second role as gatekeepers, managing or constraining flows of knowledge and information. This paper aims to analyse the dual role of CSOs in the management of chemical ris

An investigation of routes to cancer diagnosis in 10 international jurisdictions, as part of the International Cancer Benchmarking Partnership : Survey development and implementation

This paper describes the methods used in the International Cancer Benchmarking Partnership Module 4 Survey (ICBPM4) which examines time intervals and routes to cancer diagnosis in 10 jurisdictions. We present the study design with defining and measuring time intervals, identifying patients with cancer, questionnaire development, data management and analyses. Design and setting: Recruitment of part

Lingonberries alter the gut microbiota and prevent low-grade inflammation in high-fat diet fed mice

Background: The gut microbiota plays an important role in the development of obesity and obesity-associated impairments such as low-grade inflammation. Lingonberries have been shown to prevent diet-induced obesity and low-grade inflammation. However, it is not known whether the effect of lingonberry supplementation is related to modifications of the gut microbiota. The aim of the present study was

Low-level exposure to lead, blood pressure, and hypertension in a population-based cohort

Background: Environmental lead exposure is a possible causative factor for increased blood pressure and hypertension, but large studies at low-level exposure are scarce, and results inconsistent. Objective: We aimed to examine the effects of environmental exposure to lead in a large population-based sample. Methods: We assessed associations between blood lead and systolic/diastolic blood pressure

Salt-inducible kinase 2 and -3 are downregulated in adipose tissue from obese or insulin-resistant individuals : implications for insulin signalling and glucose uptake in human adipocytes

AIMS/HYPOTHESIS: Salt-inducible kinases (SIKs) are related to the metabolic regulator AMP-activated protein kinase (AMPK). SIK2 is abundant in adipose tissue. The aims of this study were to investigate the expression of SIKs in relation to human obesity and insulin resistance, and to evaluate whether changes in the expression of SIKs might play a causal role in the development of disturbed glucose

An international study of hospitalized cancer patients’ health status, nursing care quality, perceived individuality in care and trust in nurses : A path analysis

Background Providing high quality nursing care for patients with malignancies is complex and driven by many factors. Many of the associations between nursing care quality, trust, health status and individualized care remain obscure. Objective To empirically test a model of association linking hospitalized cancer patients’ health status, nursing care quality, perceived individuality in care and tru

Metformin ameliorates dysfunctional traits of glibenclamide- and glucose-induced insulin secretion by suppression of imposed overactivity of the islet nitric oxide synthase-no system

Metformin lowers diabetic blood glucose primarily by reducing hepatic gluconeogenesis and increasing peripheral glucose uptake. However, possible effects by metformin on beta-cell function are incompletely understood. We speculated that metformin might positively influence insulin secretion through impacting the beta-cell nitric oxide synthase (NOS)-NO system, a negative modulator of glucose-stimu

Work disability in newly diagnosed patients with primary sjögren syndrome

Objective. To study longterm work disability and possible predictors in newly diagnosed patients with primary Sjogren syndrome (pSS). Methods. Because we wanted to include only patients with full work availability potential, eligible patients were aged 18-62 years. Fifty-one patients (mean age 46 yrs, range 18-61 yrs, 50 women) diagnosed with pSS between January 2001 and December 2012 were include