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Increased lung weight in fatal intoxications is not unique to opioid drugs

Fatal intoxications with opioids are known to be associated with an increased lung weight, as well as with brain and pulmonary edema and urinary retention. However, there is evidence to suggest that fatal intoxications with non-opioid substances are also associated with increased lung weight; however, the latter aspect has not been comprehensively analyzed. To determine to what extent opioid and n

The Sustainability Potential of Upcycling

The upcycling trend has received renewed attention in the past few years due to growing concerns for the environment related to increased resource consumption and waste volumes. Indeed, cities across the world are supporting resource upcycling initiatives by establishing do-it-yourself (DIY) repair cafes and makerspaces as a means to transform societies towards sustainable develop-ment. However, t

SMS121, a new inhibitor of CD36, impairs fatty acid uptake and viability of acute myeloid leukemia

Acute myeloid leukemia (AML) is the most common form of acute leukemia in adults and the second most common among children. AML is characterized by aberrant proliferation of myeloid blasts in the bone marrow and impaired normal hematopoiesis. Despite the introduction of new drugs and allogeneic bone marrow transplantation, patients have poor overall survival rate with relapse as the major challeng

Pragmatic design solution to decarbonize building industry through a low temperature district network

The European Union’s aim to decarbonize the building stock by 2050 requires significant reductions in the energy use for space heating and cooling. One such solution to decarbonization could be energy sharing between buildings. This paper presents the potential for energy saving and subsequent reduction in carbon emission with a low temperature district network in an energy community based in Malm

A Cross-Sectional Study Demonstrating a High Prevalence of Skin Rash to Diabetes Medical Devices : An Underestimated Problem

Background: Adverse skin reactions to continuous glucose monitors (CGMs) and devices for continuous subcutaneous insulin infusions (CSIIs) (“diabetes medical devices” (MDs)) are well known. However, epidemiological studies on prevalence and skin rash details are lacking. The objective of this study was to describe the prevalence and details of skin rash to diabetes MDs in adults with type 1 diabet

The superantigen SEA binds to human γδ T cell receptor and activates γδ T cells with moderate MHC class II dependence

Bacterial toxins, called superantigens, are produced by Staphylococcus aureus and are known to activate γδ T cells. γδ T cells contribute to long-lasting immunity against bacterial skin infections caused by S. aureus. γδ T cells are a distinct subgroup of T cells containing the T cell receptor (TCR) γ and δ chains. The γδ TCR harbouring the variable chains TRGV9/TRDV2 is the most common TCR in hum

Infective endocarditis caused by Gemella–a retrospective registry-based study

Purpose: Infective endocarditis (IE) is diagnosed using the Duke criteria, which were updated in 2023. In the Duke-ISCVID 2023 criteria, Gemella was recognised as a typical IE pathogen. This study investigates the impact of this change and compares the clinical characteristics of Gemella IE to IE caused by other pathogens. Methods: Data on IE caused by Gemella species and other pathogens was retri

Neuronal CD59 isoforms IRIS-1 and IRIS-2 as regulators of neurotransmitter release with implications for Alzheimer’s disease

We have previously demonstrated that the intracellular, non-GPI anchored CD59 isoforms IRIS-1 and IRIS-2 (Isoforms Rescuing Insulin Secretion 1 and 2) are necessary for insulin secretion from pancreatic β-cells. While investigating their expression across human tissues, we identified IRIS-1 and IRIS-2 mRNA in the human brain, though their protein expression and function remained unclear. This stud

Bevisvärdering vid våldtäkt - med fördjupning på stödbevisning

Våldtäkt är ett ord som väcker många känslor och associationer hos människor i dagens samhälle. Alla har på något sätt kommit i kontakt med det, även om han eller hon inte själv varit drabbad eller känner någon som har. Med jämna mellanrum är våldtäkt och sexuella övergrepp i stort ett stort och hett ämne i media. Tyvärr speglar inte alltid deras bild av hur det ser ut, den som finns i verkligheteRape is a word that arouses many feelings and associations of people in today's society. All have somehow come into contact with it, even if he or she has not personally been affected or knows someone who has. Periodically, the rape and sexual abuse in general is a great and hot topic in the media. I do not always reflect their view of how it looks in the real world. It's easy to think and

IKEA varuhus - Stomsystem och konstruktionshöjder

For the design of a building, you must take into account a range of parameters. These parameters often differ from place to place. It is common that each building be designed with regards to weather, purpose and its useful life expectancy. When a material or a structural unit is subjected to external influences, changes occur, for example deflections. Each IKEA-store, with their various components

Stödcentrum for young crime victims - organizations cooperation for development

Author: Martina Wikås & Anette Johansson Title: Stödcentrum for young crime victims- organizations cooperation for development Supervisor: Carina Tigervall Assessor: Katarina Jacobsson The purpose of this study was to examine how Stödcentrum for young crime victims were perceived by other collaborators that the organization cooperate with and how the collaboration works. The current participa

”Jag är olika hela tiden” – En kvalitativ studie om ungdomars roller och kollektiva identitetskapande i olika delar av Göteborg

“I’m different all the time” – A qualitative study of young people’s roles and collective identity formation in different parts of Gothenburg The purpose of this study was to compare young people’s view of their neighborhoods, and what significance the residential area has for their collective identity formation. Young people living in a residential area with a low proportion of native Swedes, lo

From Positioning to Practice – Brand Positioning in an Over-Communicated Society

The purpose of this thesis is to identify the whole positioning process by means of existing positioning theories as well as interviews with marketing practitioners and consumers. Furthermore, the authors wish to provide the reader with an overview of the complete positioning process as well as how it is used in practice today in order to better understand how well suited positioning theories are

Arbetsrättsliga rättigheter och skyldigheter vid distansarbete

Syftet med denna examensuppsats är att utreda en rad arbetsrättsliga rättigheter och skyldigheter, som kan uppstå vid distansarbete. De områden jag har valt att fokusera på är arbetsbristuppsägningar och turordning, arbetsledningsrätt, arbetsskyldighet och arbetstid samt arbetsmiljö. Två utgångspunkter för arbetet har varit distansarbetsutredningen, SOU 1998:115, och distansarbetsavtalet, som trädMy thesis aims to assess different problems in employment law when dealing with teleworkers. I have chosen to focus on redundancy dismissals and seniority right, the managerial prerogative, the duty to work, working hours and working environment. Two starting points are the Government Inquiry Report on telework, SOU 1998:115, and the telework agreement, which entered into force in July 2002 betwee

Utbildning i informationskompetens - en litteraturstudie av förhållandet mellan forskning och praktik

This Master’s thesis in library and information science deals with the relationship between research and practice of information literacy education. Information literacy is a common field of research and many theories and models have been developed through the years. The concept is widely used in society and one goal for educational institutions is to train students to become information literate.

The mobility of employees within the EU, and the Eures Network

En sammanfattning av uppsatsen på maximalt 8000 tecken. This thesis is mainly dealing with the mobility of the employees within the borders of the European Union. Legislative framework from the EU is favourable and the Commission has set as one of it goals to promote the migration. Globalisation trends and contemporary business concepts need people who are mobile on the other hand. But migration n

End-of-life vehicles management in Europe - Driving the Change

End-of-life management of cars in Europe is regulated by a common legislative framework since 2000, when the Directive 2000/53/EC on end-of-life vehicles (ELVs) was adopted. The objectives of this legislation are: prevention of waste from ELVs through design improvements, and facilitating better recycling and treatment of ELVs by improving environmental performance of treatment facilities and atta