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Seasonality of month of birth differs between type 1 diabetes patients with pronounced beta-cell autoimmunity and individuals with lesser or no beta-cell autoimmunity

Objective: To establish whether children with type 1 diabetes mellitus (T1D) with signs of pronounced beta-cell-specific autoimmunity as reflected by high autoantibody titers or positivity for several beta-cell-specific autoantibodies show a different pattern of month of birth (MOB) compared with children with T1D and low beta-cell autoimmunity and that of the general population. Research design a

Effects of ozone depletion and increased ultraviolet-B radiation on northern vegetation

The stratospheric ozone layer has been depleted at high and mid-latitudes as a consequence of man's pollution of the atmosphere, and this results in increasing ultraviolet-B radiation at ground level. We investigate the effects of further radiation increases on plants and ecosystems by irradiating natural sub-Arctic and Arctic vegetation with artificial W-B radiation in field experiments extending

Deceased, disabled or depressed - a population-based 6-year follow-up study of elderly people with depression

The prognosis of depression in elderly people is reported as poor, with high mortality and high rate of non-recovery. The aim of this study was to investigate the outcome after 6 years in a broader perspective. In addition to the risk of dying, we also estimated the risk of moving to long-term care, and having a depression in a re-screening event after 6 years. In 1993, a screening event for depre

Sentinel node biopsy for breast cancer larger than 3 cm in diameter

Background: Sentinel node biopsy (SNB) is a standard staging procedure in early breast cancer. Its suitability for larger tumours has been questioned. This study evaluated the reliability of SNB in women with invasive breast cancer larger than 3 cm in diameter who were clinically axillary node negative. Methods: Some 109 women with a turnout larger than 3 cm on pathological analysis were identifie

Reinstitutionalisation in mental-health care: comparison of data on service provision from six European countries

Objective To establish whether reinstitutionalisation is occurring in mental health care mid, if so, with What variations between Western European countries. Design Comparison of data on changes in service provision. Setting Six European countries with different traditions of mental health care that have all experienced deinstitutionalisation since the 1970s - England, Germany, Italy, the Netherla

Morphological variation in Scandinavian populations of the diploid-tetraploid species pair Anthericum ramosum and Anthericum liliago (Anthericaceae)

Both members of the diploid-tetraploid species pair Anthericum ramosum L. and Anthericum liliago L. occur as geographically disjunct isolates on the margins of their northern range in Scandinavia. Variation in floral morphology was studied in 33 populations of A. ramosum from four geographic regions and 25 populations of A. liliago from seven regions in Scandinavia. Tepal shape was characterized w

Effects of grassland abandonment, restoration and management on butterflies and vascular plants

When semi-natural pastures are abandoned, specialized grassland species are lost as a consequence of succession. As a counter-measure, previously abandoned grasslands may be restored by clearing shrubs and trees and re-introducing grazing livestock. In order to examine the effects of this type of habitat restoration, we compared species richness of plants and of specialized plants thought to be de

Diet in the aetiology of ulcerative colitis: A European prospective cohort study

Background/Aims: The causes of ulcerative colitis are unknown, although it is plausible that dietary factors are involved. Case-control studies of diet and ulcerative colitis are subject to recall biases. The aim of this study was to examine the prospective relationship between the intake of nutrients and the development of ulcerative colitis in a cohort study. Methods: The study population was 26

Mate choice, male condition-dependent ornamentation and MHC in the pheasant

The Hamilton and Zuk model predicts that genes for resistance to various pathogens may be continuously heritable due to selection disequilibria caused by coadaptional cycles of hosts and pathogens. The model further suggests that the expression of male secondary ornaments is condition-dependent and that only individuals with superior genetic disease resistance and vigour can fully express exaggera

Copper allergy from dental copper amalgam?

A 65-year-old female was investigated due to a gradually increasing greenish colour change of her plastic dental splint, which she used to prevent teeth grinding when sleeping. Furthermore, she had noted a greenish/bluish colour change on the back of her black gloves, which she used to wipe her tears away while walking outdoors. The investigation revealed that the patient had a contact allergy to

Homeward bound: Introducing a four-domain model of perceived housing in very old age

The aim of this article is to introduce an integrative and more comprehensive approach to understanding and measuring perceived housing in old age. First, four conceptual domains of subjective housing were introduced, based on the assumption that each of the domains brings a unique perspective to the understanding of perceived housing: housing satisfaction, usability in the home, meaning of home a

The effect of inbreeding on fluctuating asymmetry in Scabiosa canescens (Dipsacaceae)

Developmental instability and fluctuating asymmetry (FA) describe the inability of organisms to correct for random accidents under development and has become a major but controversial topic in evolutionary biology. Theoretical models predict that the level of FA should increase as a result of inbreeding, but empirical results are ambiguous. Moreover, the relationship between fitness and FA is stil

Age, bodyweight, smoking habits and the risk of severe osteoarthritis in the hip and knee in men

Background: The objective of this study was to estimate the risk of severe osteoarthritis, with the need for arthroplasty, in the knee and/or hip according to body mass index (BMI) both within a normal range and in persons with high BMI. Furthermore, we wanted to study the significance of smoking. Methods: This study identifies male construction workers participating in a national health control p

Social capital, the miniaturisation of community and self-reported global and psychological health.

Social capital is often operationalised as social participation in the activities of the formal and informal networks of civil society and/or as generalised trust. Social participation and trust are two aspects of social capital that mutually affect each other, according to the literature. In recent years there has been an increased attention to the fact that generalised trust decreases for every

Persistent pain after groin hernia surgery: a qualitative analysis of pain and its consequences for quality of life

Despite a high prevalence of persistent groin pain after hernia repair, the specific nature of the pain and its clinical manifestation are poorly known. The aim of this study was to determine the type of post-herniorrhaphy pain and its influence on daily life. In order to assess long-term pain qualitatively and to explore how it affects quality of life, 100 individuals with persisting pain, identi

Nursing care at night: An evaluation using the night nursing care instrument

Introduction Night nurses carry overall nursing responsibility for approximately half the time that patients spend in hospital. However, there is a paucity of literature that focuses on nursing care provided at night. Aim The aim of this study was to evaluate nursing care provided at night from the perspective of both nurses and patients. Methods The study, which had an evaluative and a comparativ