It is known that parasympathetic, sympathetic and sensory nerves innervate the islets and that these nerves harbor both classical neurotransmitters and neuropeptides. However, the neural influence on islet hormone release is complex and not yet fully understood A recently discovered pancreatic neuropeptide is pituitary adenylate cyclase-activating polypeptide (PACAP). The aim of this thesis was to

PurposeThe purpose of this paper is to explore how witnessing workplace incivility from coworkers and supervisors relates to instigating incivility toward others. A further aim was to investigate if witnessed incivility is indirectly related to instigated incivility via perceived stress and low job satisfaction. An additional aim was to study if control, social support and job embeddedness moderat

This report aims at providing information on principles that should be considered during planning, establishment and maintenance of work zones, and inspection works. An extensive literature review has been done within the project and some of the results, e.g. of previous CEDR-projects, are included in IRIS. However, not all findings of recent studies are mentioned, as the goal was to keep the repoThis report aims at providing information on principles that should be considered during planning, establishment and maintenance of work zones, and inspection works. An extensive literature review has been done within the project and some of the results, e.g. of previous CEDR-projects, are included in IRIS. However, not all findings of recent studies are mentioned, as the goal was to keep the repo

Limited guidance is available to engineers on how people's walking speed in smoke can and should be represented in the fire safety design process of underground transportation systems, such as road and rail tunnels. To address this issue, the behaviour and movement of people in case of evacuation due to a fire in underground transportation systems has been investigated. In this paper, the relation

Key message: A 6–9 month backward time shift of the carbon uptake gave the highest correlation between annual biomass increment and carbon uptake in this old even aged forest. Abstract: Plants’ carbon uptake and allocation to different biomass compartments is an important process for both wood production and climate mitigation. Measurements of the net ecosystem carbon dioxide exchange between ecos

Background: There exist few recovery and occupation-based interventions for mental health service users. Balancing Everyday Life (BEL) is a new occupation-based lifestyle intervention that was created to fill this need. Aim: To gain group leaders’ and participants’ perspectives of the BEL intervention content and format, including factors that helped, hindered, and could be improved. Methods: A co

The genetic architecture of common traits, including the number, frequency, and effect sizes of inherited variants that contribute to individual risk, has been long debated. Genome-wide association studies have identified scores of common variants associated with type 2 diabetes, but in aggregate, these explain only a fraction of the heritability of this disease. Here, to test the hypothesis that

Objective: To validate a 7-day estimated dietary record routine with standardized portion sizes and household measuring in a clinical setting with the doubly labelled water (DLW) method as the reference method. Design: Energy expenditure was measured with deuterium (2H) and oxygen-18 (18O), and water loss was estimated by 2H dilution as part of the DLW measurements. Energy and water intake was mea

Protein-coding genetic variants that strongly affect disease risk can yield relevant clues to disease pathogenesis. Here we report exome-sequencing analyses of 20,791 individuals with type 2 diabetes (T2D) and 24,440 non-diabetic control participants from 5 ancestries. We identify gene-level associations of rare variants (with minor allele frequencies of less than 0.5%) in 4 genes at exome-wide si

The paper analyses dwell time delays for commuter trains in Stockholm and Tokyo. In both cities, small dwell time delays of at most five minutes make up around 90% of the total delays. Therefore, it is valuable to understand and deal with these disturbances. To this end, we use high resolution data on dwell times and passenger counts from both countries over the last several years. We find that thThe paper analyses dwell time delays for commuter trains in Stockholm andTokyo. In both cities, small dwell time delays of at most five minutes makeup around 90% of the total delays. Therefore, it is valuable to understandand deal with these disturbances. To this end, we use high resolution data ondwell times and passenger counts from both countries over the last severalyears. We find that these d

Objective: To assess and compare the accuracy of imaging methods (ultrasonography (US), computed tomography (CT), angiography, arterially enhanced CT with computed tomographic arterial portography (CTA)), biochemical analyses, and surgical assessment during the operation, in detecting the presence or absence of hepatic metastases in patients with colorectal cancer. Design: Open study. Setting: Uni

Hymns to Unknown Heroines part III – Elna, 2015 Slide and sound installationHymns to Unknown Heroines, part III is the latest iteration of a multifaceted work. The starting point was an anonymous photographic archive from the 1920s that depicts a Scottish family over several years. Many of the photographs portray women engaged in recreational activities, portraying an undemanding lifestyle that ca

Apolipoprotein A-I (ApoA-I)-related amyloidosis is a rare disease caused by missense mutations in the APOA1 gene. These mutations lead to protein aggregation and abnormal accumulation of ApoA-I amyloid fibrils in heart, liver, kidneys, skin, nerves, ovaries, or testes. Consequently, the carriers are at risk of single- or multi-organ failure and of need of organ transplantation. Understanding the b

Grass ley and whole-crop cereals used for biogas production are often finely chopped for subsequent ensiling and anaerobic digestion. Chopping can impact not only ensiling stability, digestibility and risk of process hick-ups in the digester but also harvesting capacity and fuel consumption. Based on field experiment data, the aim of this study was to investigate how three different nominal cuttin

Background and purpose — Spasticity is often regarded as a major cause of functional limitation in children with cerebral palsy (CP). We analyzed the spasticity development with age in the gastrosoleus muscle in children with CP. Children and methods — This is a longitudinal cohort study of 4,162 children (57% boys) with CP born in 1990–2015, monitored using standardized follow-up examinations in